From empirical exploration to data-driven innovation: The role of artificial intelligence in pharmaceutical taste masking [0.03%]
从经验探索到数据驱动创新：人工智能在药物掩味中作用
Chun Qiao,Jinru Hu,Yuxin Jin et al.
Chun Qiao et al.
The aversive taste of pharmaceutical formulations, especially bitterness, has been identified as a significant barrier to patient compliance. Taste masking technologies have emerged as significant approaches to improve the acceptability of ...
Biomembrane-Derived vesicles for targeted cancer Therapies: Novel treatment avenues from Cells, Bacteria, and extracellular sources [0.03%]
源自生物膜的癌症治疗囊泡：来自细胞、细菌和细胞外来源的新治疗途径
Soraia Santos,Joana Lopes,Daniela Lopes et al.
Soraia Santos et al.
Nanovesicles (NVs) derived from biological membranes offer promising opportunities in the realm of ultra-precise cancer therapy, with proven therapeutic efficacy and safety profiles. These biomimetic NVs possess a versatile liposome-like st...
Impact of terminal groups on PLGA degradation rate and their role in sustained release of cyproterone acetate [0.03%]
端基对PLGA降解率的影响及其在醋酸环丙孕酮缓释中的作用
Qien Zhao,Junhui Yang,Jialin Liu et al.
Qien Zhao et al.
Poly(lactic-co-glycolic acid) (PLGA) is the most commonly used commercially available polymeric pharmaceutical excipient for developing injectable long-acting release products. Its degradation rate is influenced by factors, such as molecula...
Parag Roy,Oisín N Kavanagh
Parag Roy
Every month thousands of patients are treated with ocular ciprofloxacin, yet crystalline deposits form on the surface of the cornea in one in ten patients. This occurs due to a pH shift when the formulation is instilled onto the eye, since ...
Oxygenated collagenase nanoliposomes for deep photodynamic therapy via remodelling the tumor extracellular matrix [0.03%]
氧合胶原酶纳米脂质体通过重塑肿瘤细胞外基质进行深层光动力治疗
Xinyi Xu,Jianhua Han,Xuefang Lou et al.
Xinyi Xu et al.
Melanoma is highly aggressive and remains difficult to treat. Traditional treatment options often result in damage to normal tissues and a high rate of recurrence. Conventional photodynamic therapy (PDT) is limited by poor light penetration...
Corrigendum to "Combination of magnetic targeting with synergistic inhibition of NF-κB and glutathione via micellar drug nanomedicine enhances its anti-tumor efficacy." [Eur. J. Pharm. Biopharm. 155 (2020) 162-176] [0.03%]
磁性 targeting与协同抑制NF-κB和谷胱甘肽的结合通过纳米药物胶束增强其抗肿瘤功效的纠错[Eur. J. Pharm. Biopharm. 155 (2020) 162-176] Corrections
Kholod A Elhasany,Sherine N Khattab,Adnan A Bekhit et al.
Kholod A Elhasany et al.
Review of design strategies for active targeted drug delivery systems for pancreatic cancer [0.03%]
胰腺癌活性靶向药物递送系统的设计策略综述
Aysha Rahmatulla,Xiaoling Bi,Ping Wang et al.
Aysha Rahmatulla et al.
Pancreatic cancer (PC) is frequently referred to as the "king of cancers" due to its high mortality rate and poor prognosis. Chemotherapy drugs of a traditional nature are confronted with a multitude of challenges, including poor water solu...
A bedside-savior for insomnia and anxiety disorders: melatonin/buspirone hydrochloride compound oral fast-dissolving film [0.03%]
一种治疗失眠和焦虑障碍的床头救星：褪黑素/盐酸溴吡斯的明复方口腔速溶膜
Xiaoyan Liu,Chenxiao Chu,Qianru Lu et al.
Xiaoyan Liu et al.
Insomnia and anxiety disorders are highly prevalent conditions that significantly impair daily functioning. Notably, a bidirectional relationship exists between these two disorders: heightened cortical excitability secondary to anxiety disr...
Development of Piperine/HPβCD-Loaded PVA-Coated iron oxide nanoparticles in in situ gel for enhanced retinal delivery and Anti-VEGF activity [0.03%]
开发用于增强视网膜递送和抗VEGF活性的生物粘附凝胶中的PVP包覆铁氧体纳米颗粒递送胡椒碱/HPβCD研究
Phatsawee Jansook,Hay Man Saung Hnin Soe,Theingi Tun et al.
Phatsawee Jansook et al.
Piperine (PIP) is a potential therapeutic agent for retinal diseases; however, its poor aqueous solubility limits its ocular bioavailability. To overcome this limitation, a novel nanocarrier system was fabricated through the adsorption of P...
Pharmacomagnetography of floating gastroretentive systems in vivo in different prandial states evaluated by AC biosusceptometry [0.03%]
以空腹和餐后状态评估浮置胃滞留系统的体内药剂磁图——交流生物磁导率法
Gustavo Serafim Rodrigues,Laís Pereira Buranello,João Miguel Barboza et al.
Gustavo Serafim Rodrigues et al.
In recent decades, the development of effective therapies with minimal adverse effects has become a major challenge in the pharmaceutical field. Despite its popularity, oral administration faces limitations related to the physiological vari...