Associations between sedentary behavior and allostatic load: The 1970 British Cohort Study [0.03%]
久坐行为和代偿负荷之间的关系:来自1970年英国队列研究的证据
Aiden J Chauntry,Jake C Diana,Qinghua Li et al.
Aiden J Chauntry et al.
Background: Chronic/repeated exposure to psychological stressors can induce high allostatic load (AL), or multisystem physiological dysregulation, which increases cardiometabolic disease (CMD) risk. While moderate-to-vigo...
Alteration of colonic circadian rhythm by gut microbiota dysbiosis and SCFA reduction links chronic stress-induced depressive-like behavior [0.03%]
肠道菌群失调和SCFA减少所致结肠昼夜节律紊乱与慢性应激诱导的抑郁行为有关
Xuli Wang,Ruisi Liu,Yudong Lin et al.
Xuli Wang et al.
Background: Chronic stress partially leads to depression through the gut-brain axis, yet the underlying multi-level mechanisms remain unclear. This study aims to delineate the pathway from chronic restraint stress (CRS) t...
Telomere trajectories from early adolescence to adulthood following early institutionalization: Protective effects of foster care in the Bucharest Early Intervention Project [0.03%]
保加利亚早年干预项目中机构抚养对青少年成年前后端粒轨迹的影响:寄养照顾的保护效应
Michelle M J Mens,Nigel Walsh Harriman,Ellen Jopling et al.
Michelle M J Mens et al.
Background: Early institutional rearing is associated with adverse biological and health outcomes in later life, including accelerated cellular aging as measured by telomere length. However, the extent to which foster car...
Association of ADHD symptoms with the interactions within and between the HPA axis and melatonin system characterized by hair-based biomarkers [0.03%]
基于毛发生物标志物的HPA轴和褪黑素系统内部及系统间的交互作用与注意缺陷多动障碍症状关联性研究
Sanjun Yi,Xuliang Hou,Guirong Xu et al.
Sanjun Yi et al.
Background: Attention deficit hyperactivity disorder (ADHD) is characterized by abnormal functions of neuroendocrine systems with circadian rhythm, especially for the hypothalamic-pituitary-adrenal (HPA) axis and the mela...
Unipolar depressed inpatients without comorbid personality disorder exhibit elevated IL-6 levels at admission and a decrease after discharge: A longitudinal study [0.03%]
纵向研究:单极障碍住院患者在入院时没有并发人格障碍但IL-6水平升高,出院后降低
Bruno Perosa Carniel,Giulio Bertollo Alexandrino,Luísa Monteiro Burin et al.
Bruno Perosa Carniel et al.
Background: One-third of patients with unipolar depression (UD) do not achieve remission after treatment. There is a growing interest in the role of inflammation in the pathogenesis of UD; however, no study has evaluated ...
Gina-Isabelle Henze,Jens C Pruessner
Gina-Isabelle Henze
Stress engages coordinated psychological, neuroendocrine, autonomic, and neural processes that enable adaptation to environmental demands but may contribute to vulnerability when stress is prolonged, uncontrollable, or socially evaluative. ...
Effects of sex, pubertal stage, and pubertal hormones on frontal and limbic responses to fearful and happy faces during early adolescence [0.03%]
性别、青春期阶段及性激素对青少年早期杏仁核和前额皮层处理恐惧与快乐面孔反应的影响
Yiming Qian,Johnna R Swartz,Marjolein E A Barendse et al.
Yiming Qian et al.
Adolescence is a key stage of brain development marked by heightened emotional reactivity, with variability across individuals and sexes. Puberty onset also initiates a cascade of changes that influence how the brain responds to social-emot...
The neuro-immune gap in systemic autoimmunity: Integrated dysregulation of the HPA axis and autonomic flexibility in SLE and Sjögren's syndrome [0.03%]
自身免疫性疾病中神经-免疫调节的缺失:SLE和舍格伦综合征患者HPA轴及自主神经系统功能障碍导致的整合失调
Cihat Uçar,Elif İnanç,Faruk Dişli et al.
Cihat Uçar et al.
Background: While systemic inflammation is the hallmark of Systemic Lupus Erythematosus (SLE) and Sjögren's Syndrome (SS), the failure of endogenous "anti-inflammatory brakes" remains poorly understood. The Hypothalamic-...
Observed positive support and cortisol reactivity/recovery among heterosexual cisgender and sexually and gender diverse couples [0.03%]
异性顺性别和性/性别多样伴侣中的支持与皮质醇反应/恢复关系的正向关联研究
Silke Jacmin-Park,Beáta Bőthe,Robert-Paul Juster et al.
Silke Jacmin-Park et al.
Positive romantic relationships are linked to physical health via stress buffering. Although a growing number of studies have found that couple interactions before or after the Trier Social Stress Test (TSST) modulate cortisol reactivity an...
Stress responses and habituation across biological systems: The role of trait and state resilience [0.03%]
跨生物系统的应激反应和习惯化:性格复原力和状态复原力的作用
Marie-Christin Barthel,Markus Muehlhan,Nina Alexander et al.
Marie-Christin Barthel et al.
Background: Resilience is assumed to shape how individuals respond and adapt to stress, potentially through mechanisms such as habituation to repeated exposure. However, few studies have tested links between self-reported...