The creative mind in the shadow of depressive symptoms: Epigenetic variation in HPA axis genes is associated with the link between depressive symptoms and creative personality [0.03%]
抑郁症状下的创造性思维：HPA轴基因表观遗传变异与抑郁症状和创造性人格之间的关系
Daniel Feinmesser,Stav Shohat,Roi Gerda et al.
Daniel Feinmesser et al.
This cross-sectional study investigated the relationship between depressive symptoms and creative personality through the lens of epigenetic modifications within Hypothalamic-Pituitary-Adrenal (HPA) axis genes. By analyzing DNA methylation ...
Economic disparities in parental hair cortisol are associated with externalizing behavior in children [0.03%]
父母头发皮质醇的经济差异与儿童外化行为有关
Jordan Strack,Melissa Hansen,Lydia Jacobs et al.
Jordan Strack et al.
Socioeconomic disadvantage has been repeatedly found to increase risk for internalizing and externalizing problems in children. Socioeconomic disadvantage is theorized to exert these effects in part through its effects on parent and child s...
Multimodal brain-gut-sleep phenotypes predict delirium, long-term cognitive decline, and survival after colorectal cancer surgery [0.03%]
脑-肠-睡眠多模态表型可预测结直肠癌手术后的谵妄、长期认知衰退和生存率
Shengjie Pan,Gang Wang
Shengjie Pan
Background: Neuroimmune, circadian, autonomic, and gut-brain processes jointly shape vulnerability to postoperative delirium and long-term cognitive decline, yet their integrated contribution remains unclear. ...
Family member bereavement, salivary telomere length, and all-cause mortality in older adults: Findings from the Health and Retirement Study [0.03%]
老年亲属丧失、唾液端粒长度和全因死亡率：来自健康与退休研究的发现
Michelle Chang,Patrick A Wilson,Theodore F Robles
Michelle Chang
The biological aging mechanisms by which loss exposure relates to mortality are not well-understood, particularly among communities of color. In this pre-registered, longitudinal study, we evaluated whether salivary telomeres mediate associ...
Stacey N Doan,Dylan J Hoell,Thomas E Fuller-Rowell
Stacey N Doan
A growing literature has sought to characterize the physiological correlates of depression, particularly with respect to inflammatory hypothalamic-pituitary-adrenal functioning and inflammation. These systems are intricately interrelated, b...
Association between allostatic load and incident dementia, and race/ethnic disparities in the association in the U.S. health and retirement study [0.03%]
美国健康与退休研究中allostate负荷与新发痴呆之间的关系及该关系中的种族差异
Mohammed U Kabeto,Manoj Sharma,Dawn Ford et al.
Mohammed U Kabeto et al.
Objective: Allostatic load (AL), the cumulative physiological burden of chronic stress, is a significant health issue and has been linked with adverse health outcomes, including cognitive decline. We examined the associat...
Hypothalamic-pituitary-adrenal axis attenuation following child sexual abuse distinguishes posttraumatic stress trajectories from late adolescence to midlife [0.03%]
童年期性虐待所致的下丘脑-垂体-肾上腺轴功能减退可将青年晚期至成年中期创伤后应激障碍病程分型
Hannah Swerbenski,Zhi Li,Frank W Putnam et al.
Hannah Swerbenski et al.
Biological embedding describes the process of responsive developmental adaptation whereby stress "gets under the skin." Applied to the endocrine system, early chronic stress exposure may contribute to hypothalamic-pituitary-adrenal (HPA) ax...
Long-term offspring loss in lactating rats: Neurobiological and emotional consequences in a novel animal model [0.03%]
长期后代丢失对泌乳大鼠的神经生物学和情感后果：新动物模型的研究
Luisa Demarchi,Alice Sanson,Anna-Lena Boos et al.
Luisa Demarchi et al.
The maternal bond is a vital social connection that supports the survival and well-being of both the caregiver and offspring. Disruption of this bond, particularly following offspring loss, can result in profound trauma with long-lasting co...
Pubertal neuroendocrine network characteristics and sex differences: A hair-based hormone network study [0.03%]
青春期神经内分泌网络特征及性别差异：基于毛发激素的网络研究
Xuliang Hou,Mingjun Xie,Sanjun Yi et al.
Xuliang Hou et al.
Background: Puberty is a critical developmental stage involving profound remodeling of neuroendocrine and neuromodulatory systems. While hormonal changes from a single system have been well studied, the systemic coordinat...
Bias in hair cortisol measures for psychological stress: Self vs. professional collection [0.03%]
毛发皮质醇测量的心理偏倚：自我收集与专业收集的区别
Heather Gatny,William Axinn,Dirgha Ghimire et al.
Heather Gatny et al.
Population-representative samples of hair-based cortisol have the potential to revolutionize studies of psychological stress. However, to integrate hair-based cortisol measurement into large-scale studies, it is crucial to understand the li...