Distinctions in theory of mind (ToM) and serum chemokine profiles between adolescent patients with depressive disorder with suicidal attempt and non-suicidal counterparts: A case-control study [0.03%]
青少年抑郁症患者自杀未遂组和非自杀组理论心智能力及血清细胞因子谱特征差异:一项病例对照研究
Hongyu Zheng,Shuai Liu,Longxing Liu et al.
Hongyu Zheng et al.
Background: Substantial evidence suggests an association between suicide-related behaviors in patients with depressive disorders and impaired social cognitive functioning and immune dysfunction.This study aims to identify...
The effect of GLP-1 receptor agonists on anxiety: A systematic review [0.03%]
胰高血糖素样肽-1受体激动剂对焦虑影响的系统评价
Yu Tian Yi,Yang Jing Zheng,Stavroula I Bargiota et al.
Yu Tian Yi et al.
Anxiety-like behaviors are highly prevalent and frequently co-occur with metabolic conditions such as type 2 diabetes and obesity, suggesting the potential for shared biological mechanisms. Although glucagon-like peptide-1 receptor agonists...
Positive coping enhances children's emotional wellness via neuroendocrine modulation of cortisol awakening response and hippocampal circuitry [0.03%]
积极应对通过神经内分泌调节皮质醇觉醒反应和海马回路增强儿童情感健康
Ting Tian,Boxuan Chen,Hongxing Cao et al.
Ting Tian et al.
Positive coping is a key developmental asset that supports active self-regulation in daily emotional challenges and may influence neurodevelopment through cortisol-related stress physiology relevant to hippocampal integrity and behavioral a...
Variation in DNA methylation of the oxytocin gene is associated with prosocial, reward-related, decision-making [0.03%]
催产素基因DNA甲基化的差异与利他行为和奖赏相关决策有关
Charlotte F Kroll,Nicole K Leibold,Claudia Vingerhoets et al.
Charlotte F Kroll et al.
Human and animal studies suggest a critical role for central oxytocin (OXT) in social behavior. While experimentally manipulating central OXT levels via intranasal administration is a well-suited noninvasive option in human research, existi...
Dynamic interaction between stress hormones and neutrophils promotes neutrophil extracellular trap formation with behavioral consequences [0.03%]
应激激素与中性粒细胞的相互作用促进具有行为后果的中性粒细胞胞外诱捕网的形成
Kannan Thangamani,Helder Prece,Julia Carter et al.
Kannan Thangamani et al.
Recent studies have highlighted the crosstalk between neuroendocrine responses and the immune system, but the mechanisms underlying this cooperation remain poorly understood. The stress response is associated with peripheral inflammation su...
Metabolic insights into the 3xTg-AD Alzheimer model mice: Unraveling the hypothalamic-pituitary-thyroid axis and beyond [0.03%]
关于3xTg-AD老年痴呆模型小鼠代谢的新见解:揭开下丘脑-垂体-甲状腺轴及其更深层机制的面纱
Adrienn Szabó,Szidónia Farkas,Andrea Kádár et al.
Adrienn Szabó et al.
The 3xTg-AD mouse model is widely used to study the pathomechanisms of Alzheimer's disease (AD) and to test potential therapies. During food-motivated cognitive tasks, however, increased food-directed behavior was observed in these animals,...
Beyond dose: Antipsychotic risk categories and sex-specific vulnerability to hyperprolactinemia in real-world longitudinal care [0.03%]
剂量之外:抗精神病药物的风险分类及真实世界长期治疗中男女特异性的高催乳素血症易感性
Zeynep Öztürk Yalçın,İzgi Bayraktar,Merve Kaşıkcı et al.
Zeynep Öztürk Yalçın et al.
Background: Antipsychotic-induced hyperprolactinemia is a common and clinically relevant adverse effect that may impair treatment adherence and long-term health outcomes. Although chlorpromazine-equivalent doses (CPZE) ar...
Personality traits modulate temporal dynamics and cross-system coordination of acute stress responses in virtual reality [0.03%]
人格特质调节虚拟现实中的急性应激反应的时间动态和跨系统协调作用
Hao Xu,Jie Huang,Mengzhuang Gou et al.
Hao Xu et al.
Acute stress is a primary risk factor for mental disorders. While prior virtual reality (VR) studies have utilized objective physiological measures to address biological heterogeneity, the specific temporal evolution and cross-system coordi...
Daily discrimination and inflammation patterns among Black and Hispanic adolescents [0.03%]
针对黑人和西班牙裔青少年的日常歧视和炎症模式研究
Queenisha J Crichlow,Catheryn Orihuela,Douglas A Granger et al.
Queenisha J Crichlow et al.
Discrimination has been identified as a potential contributor to health disparities, partly through its role in promoting inflammation, a key biological mechanism in the development of chronic disease. While most research has focused on adu...
Deconstructing the cortisol awakening response (CAR): Post-peak decline predicts health vulnerability in healthy females [0.03%]
皮质醇觉醒反应(CAR)的分解:峰值后的下降幅度预示健康女性的健康脆弱性
Nina Smyth,Lisa Thorn,Maria Flynn et al.
Nina Smyth et al.
Background: The cortisol awakening response (CAR) has two regulatory pathways underlying its components typically not discriminated in CAR studies. The timing of the peak, post-peak secretion and overall levels were asses...