Copper (I) nicotinate complex potentiates chemotherapy-induced apoptosis in HCC-1806 triple negative breast cancer cells: An in vitro study [0.03%]
体外研究：铜(I)烟酸酯复合物可提高三阴性乳腺癌HCC-1806细胞的化疗诱导凋亡作用
Marihan A Helal,Mohamed A Abdel-Mohsen,Elshahat A Toson
Marihan A Helal
Triple negative breast cancer (TNBC) remains a clinically challenging subtype because it lacks established molecular targets and often depends on cytotoxic chemotherapy. Although doxorubicin (DOX) and mTOR inhibitors such as Torin1 (TOR) ex...
Attack of NADH and ascorbate toward metal-activated ligand of organoiridium(III) compound [0.03%]
NADH和抗坏血酸对有机铱(III)化合物金属活化配体的攻击作用研究
Pavel Štarha,Eva Řezníčková,Slavomíra Šterbinská et al.
Pavel Štarha et al.
The half-sandwich Ir(III) compound [Ir(η5-Cp*)Cl(L1)]PF6 (1), which involves the metal-activated Schiff base ligand N-[1-(anthracene-9-yl)-methylidene]-3,5-di(pyridin-2-yl)-4H-1,2,4-triazol-4-amine (L1), was designed to incorporate a biolo...
Design, synthesis and photocatalytic activities of functionalized Re(I) bipyridine tricarbonyl complexes toward CO2 reduction and carboxylation [0.03%]
功能化rhenium(i)双吡啶三羰基配合物的设计、合成及光催化二氧化碳还原和羧化的活性研究
Phurinat Lorwongkamol,Yutaka Saga,Tetsuya Kambe et al.
Phurinat Lorwongkamol et al.
Natural metalloenzymes efficiently catalyze chemical transformations by precisely controlling the local environment around the active site, thereby enabling selective substrate activation and reaction control. This general concept has motiv...
Searching for the basis of constitutive activity in bacterial cytochrome c peroxidases [0.03%]
在细菌细胞色素c过氧化物酶中寻找固有活性的基础
Patrick H Hewitt,Marcos Tapias,Matthew A Conger et al.
Patrick H Hewitt et al.
Bacterial cytochrome c peroxidases are marked by their possession of a c-type peroxidative active site in addition to a six-coordinate His/Met-ligated c-type heme associated with electron-transfer. The majority of the reported bCcPs are ina...
Electrochemiluminescence of chlorophyll a and chemiluminescence of chlorophylls a and b [0.03%]
叶绿素a的电致化学发光和叶绿素a、b的化学发光
Ziying Zhan,Zahra Mohamad Sharif,In Lee et al.
Ziying Zhan et al.
The absolute chemiluminescence (CL) quantum efficiencies of chlorophylls a and b were measured, and the absolute electrochemiluminescence (ECL) quantum efficiency of chlorophyll a was determined. These measurements were carried out under we...
CO binding at Iron porphyrins: Reflecting on Heme model complexes to guide future electrocatalyst design [0.03%]
铁卟啉的CO结合：从血红素模型配合物看未来的电催化剂设计反思
Daelin Peel-Smith,Connor S Durfy,Eva M Nichols
Daelin Peel-Smith
Homogeneous CO2 reduction beyond CO or formate is rare, yet the limited existing examples identify the crucial role of CO-bound intermediates. Understanding the structure-property relationships that govern CO binding to Fe porphyrins is the...
The development of half-sandwich arene ruthenium(II) complexes with antifungal activity against resistant Candida albicans [0.03%]
具有抗耐药性白色念珠菌真菌活性的半夹心芳基钌(II)配合物的发展
Shiming Wu,Qian Huang,Yan Luo et al.
Shiming Wu et al.
The escalating threat of drug-resistant fungal infections, particularly invasive candidiasis caused by Candida albicans, demands the development of novel antifungal agents. Herein, we report the synthesis and evaluation of a series of half-...
Synthesis, characterization, and biological investigation of thiosemicarbazone-ruthenium(II) complexes [0.03%]
噻二唑甲烷-钌(II)配合物的合成、表征及生物活性研究
Atif Ahmad,Angelica Ellen Graminha,Anam et al.
Atif Ahmad et al.
Four novel ruthenium complexes, Ru1-Ru4, were synthesized and characterized, with the general formula [Ru(L)(bipy)(dppb)]PF6, where bipy = 2,2'-bipyridine, dppb = 1,4-bis(diphenylphosphine)butane, and L corresponds to morpholine-vanilline t...
Anticancer evaluation of ferrocene-modified half-sandwich ruthenium(II) acylhydrazone complexes against A549 cell lines [0.03%]
含铁ocene修饰半夹层钌化合物的抗肿瘤评价及对A549细胞系的作用机制研究
Yuan Gao,Xiaoshuang Li,Jia Wen et al.
Yuan Gao et al.
Owing to the intrinsic drawbacks of platinum chemotherapeutics, ruthenium(II) complexes exhibited superior performance in mechanism of action, tumor selectivity, and systemic toxicity, thus establishing themselves as a prominent research fr...
Structure and antitumor activity of cupric complexes incorporating 2-(2-pyridyl)benzimidazole derivatives [0.03%]
含2-（2-吡啶基）苯并咪唑衍生物的铜配合物的结构及抗肿瘤活性
Shanshan Wang,Xiyu Mo,Yuning Liang et al.
Shanshan Wang et al.
Six mononuclear CuII complexes, formulated as [Cu(PBDn)2(NO3)]NO3 (Cu1-Cu6) were synthesized and structurally characterized, in which PBDn (n = 1-6) represent the 2-(2-pyridyl)benzimidazole derivatives bearing the substitution groups of 7-m...