Evaluating metal complex enantiomers: Lessons from a photobiological study [0.03%]
金属配合物对映体的评估——从光生物学研究中得到的启示
Troy T Handlovic,Ge Shi,Saba Aslani et al.
Troy T Handlovic et al.
Chiral coordination complexes continue to attract interest as potential therapeutic agents, yet their stereochemical properties are rarely examined with the rigor now standard in organic drug discovery. Here we investigate whether the Δ an...
Cobalt metallochaperone-mediated maturation of nitrile hydratases: Structural and functional insights [0.03%]
钴金属伴侣介导的腈类水合酶成熟过程中的结构和功能研究
Callie Miller,Nele Hebbeler,Brian Bennett et al.
Callie Miller et al.
The Co-type nitrile hydratase activator (ɛ) protein from Pseudonocardia thermophila JCM 3095 (PtCo-type ε protein) was successfully expressed and purified, enabling the first detailed biochemical and spectroscopic characterization of Co(I...
A review on sulfonamides and their coordination compounds: Fighting diseases and catalytic applications [0.03%]
磺酰胺及其配位化合物的研究进展：抗病治病及催化应用
Mateusz Kowalik,Magdalena Stasiuk,Natalia Żukowska et al.
Mateusz Kowalik et al.
Sulfonamides belong to the most interesting classes of organic and bioactive compounds, historically introduced as the first widely used synthetic antibacterial agents. Currently, they still serve as versatile scaffolds across medicinal, co...
Mitochondrial apoptosis and DNA intercalation synergistically driven by organotin acridine-9-carboxylate complexes potent anticancer efficacy [0.03%]
有机锡吖啶-9-羧酸复合物协同驱动线粒体细胞凋亡和DNA嵌入的高效抗肿瘤功效
Zhijian Zhang,Zhongshan Zhou,Wujiu Jiang et al.
Zhijian Zhang et al.
Four organotin acridine-9-carboxylate complexes (C1-C4) were successfully synthesized by the reaction of 9-acridinecarboxylic acid (YCOOH) with organotin precursors. The structures of these complexes were systematically characterized using ...
Synthesis, encapsulation, and cytotoxic effects of new Schiff-base copper complexes [0.03%]
新的希夫碱铜复合物的合成、包封及其细胞毒效应
Lucas M Bosquetti,Vitória S Sousa,Kaio S Gomes et al.
Lucas M Bosquetti et al.
Gliomas remain one of the most lethal malignancies, with limited therapeutic options and poor prognosis under current standard-of-care regimens. Copper-based metallodrugs represent an emerging therapeutic strategy, but their clinical transl...
Synthesis, spectroscopic characterization and antimicrobial studies of oxovanadium(IV) complexes with substituted acetylacetones and pyridines [0.03%]
取代乙酰丙酮和吡啶化合物合成的四价氧化钒配合物及其光谱表征与抗菌研究
Valmiki,V L Chandraboss,C Kesava Rao
Valmiki
Monomeric six-coordinated adducts of 1,5-disubstituted bis(acetylacetonato) oxovanadium (IV) complexes having the general formula [VO(RCOCH₂COR')₂(L)] [where R = CH₃, (CH₃)4; R' = CF₃, (C4H3S); and L = 4-methylpyridine or 3-amino-4-hyd...
Design and properties of water-soluble trinuclear ruthenium complexes featuring imidazole-derived ligands [0.03%]
含咪唑衍生物配体三核钌配合物的合成及其水溶性研究
Bruno Faria Abrantes Pinheiro,Pedro Henrique de Oliveira Santiago,Nathália de Lima Martins Abichabki et al.
Bruno Faria Abrantes Pinheiro et al.
Four different fully water soluble triruthenium acetate complexes with general formula [Ru3O(CH3COO)6(L)3]Cl where L = imidazole (1), 1-(2-hydroxyethyl)imidazole (2), 1-methylimidazole (3) and 1-vinylimidazole (4) ligands were synthesized a...
A red-emissive AIE-active cycloiridium(III)-butyltin(IV) heteronuclear complex: Evaluation for A549 cancer cell theranostics [0.03%]
一种红色发射的具有聚集诱导发光效应的环铱(III)-丁基锡(IV)异核配合物及其在A549癌细胞诊疗中的应用
Xiaoshuang Li,Anyue Zhang,Yuxin Zhang et al.
Xiaoshuang Li et al.
Although cycloiridium(III) complexes and organotin(IV) compounds exhibited potential in anticancer therapy, their commonly observed aggregation-caused quenching (ACQ) effect limited the determination of targeting and anticancer mechanisms. ...
Harry B. Gray: Celebrating his career and contributions to inorganic biochemistry [0.03%]
哈利·B·格雷：纪念他职业生涯及无机生物化学贡献
John H Dawson,Kara L Bren,Alison Butler
John H Dawson
A bioinspired manganese(II)-creatine coordination polymer with anti-inflammatory potential: supramolecular framework, periodic-DFT calculations and spectroscopic study [0.03%]
一种具有抗炎潜能的类 creatine 锰(II) 生物启发型配位聚合物：超分子框架、周期性-DFT 计算和光谱研究
Otávio C da Silva Neto,Ana B N Moreira,Maria F O Martinez et al.
Otávio C da Silva Neto et al.
The synthesis, structural characterization, spectroscopic features, solubility, and anti-inflammatory properties of a novel manganese(II)-creatine coordination polymer, {[Mn(μ2-CRN)2(H2O)2](NO3)2·2H2O}n (CRN = creatine), are reported. Sin...