Improving laboratory stewardship through benchmarking: A focus on thyroid function tests ordering [0.03%]
利用实验室数据开展甲状腺功能检测合理用药提升项目
Ka Keung Chan,Suhhyun Kim,Patrick C Mathias et al.
Ka Keung Chan et al.
Objectives: Thyroid function tests, particularly thyroid-stimulating hormone (TSH) and free thyroxine (fT4), are among the most frequently ordered laboratory tests. This study evaluates longitudinal trends in thyroid test...
Implementing minimal request intervals for laboratory tests: a utilization management study across eight hospitals in South Iran [0.03%]
南伊朗八家医院实验室检验最小请求间隔的实施与使用管理研究
Babak Shirazi Yeganeh,Zahra Rabet,Zahra Afsar et al.
Babak Shirazi Yeganeh et al.
Introduction: Effective utilization management in medical laboratories is a challenge. To address this, strategies such as clinical guidelines, minimum requesting intervals (MRIs), and test request limits integrated into ...
Rasmus Søgaard Hansen,Peter H Nissen,Julie Brogaard Larsen et al.
Rasmus Søgaard Hansen et al.
Objective: Describe challenges in diagnosing protein S deficiency. Methods: A women in her late 20 s and pregnant in third trimester (G...
Choosing Wisely Canada recommendations for clinical biochemistry: test ordering for sustainable and high-quality patient care [0.03%]
加拿大临床生化领域明智选择建议：为了可持续和高质量的患者护理而订购检测项目
Daniel R Beriault,Yu Chen,Paul Yip et al.
Daniel R Beriault et al.
Laboratory Medicine is growing at a rapid rate in both the breadth of unique tests and the total number of tests performed per year. Inappropriate overutilization of laboratory tests can lead to patient harm, excessive environmental waste a...
Wide-range and high-throughput quantification of anamorelin in human plasma using ultra-high-performance liquid chromatography coupled to tandem mass spectrometry [0.03%]
一种用于人血浆中Anamorelin超宽范围高通量定量的UPLC-MS/MS方法
Takahiro Sumimoto,Ryota Tanaka,Ayaka Sato et al.
Takahiro Sumimoto et al.
Objective: Cancer cachexia is characterized by weight loss, muscle mass loss, and reduced food intake. Anamorelin is a ghrelin receptor agonist approved for the treatment of cancer cachexia. In this study, we established ...
The comparison of miRNA expression levels in Type 2 diabetes and diabetic peripheral neuropathy patients [0.03%]
2型糖尿病与糖尿病外周神经病变患者中miRNA表达水平的比较分析
Aleyna Ayaz,Sibel Kuras,Bekir Erdogan et al.
Aleyna Ayaz et al.
Objectives: We aimed to investigate the correlation between miRNA expression levels in patients with type 2 diabetes mellitus (T2DM) and diabetic peripheral neuropathy (DPN) and determine their potential functions in DPN....
Sustainable healthcare and medical laboratories: The impact of global collaborations between frameworks and initiatives [0.03%]
可持续医疗保健和医学实验室：框架与计划间全球合作的影响
Fikriye Uras
Fikriye Uras
Climate change is a pressing global challenge that requires urgent action. The Paris Agreement and the 2030 Agenda of United Nations (UN) set clear global targets for emission reduction and sustainability to limit warming to 1.5 °C. Partne...
Biomarker profiling for infection diagnosis in emergency departments: A diagnostic study evaluating C-reactive protein, procalcitonin, Club Cell Protein 16, interleukin-6, chitinase-like protein, and soluble urokinase-type plasminogen activator receptor [0.03%]
在急诊科进行感染诊断的生物标志物检测：一项评估C反应蛋白、降钙素原、俱乐部细胞蛋白16、白细胞介素-6、几丁质酶样蛋白和可溶性尿激酶型纤溶酶原激活物受体的诊断研究
Rasmus Bruhn,Helene Skjøt-Arkil,Thor Aage Skovsted et al.
Rasmus Bruhn et al.
Introduction: Diagnosing infections in emergency departments (EDs) is vital for prompt and effective treatment. This study evaluates the diagnostic accuracy of six inflammatory biomarkers-CC16, CRP, IL-6, PCT, suPAR, and ...
Venous lactate as a tool for the Risk-Stratification of patients with acute pulmonary embolism: A retrospective cohort study [0.03%]
静脉血乳酸作为急性肺栓塞患者风险分层工具的回顾性队列研究
Eun Sang Lee,Kyle E Chang,Christiana K Prucnal et al.
Eun Sang Lee et al.
Introduction: Prognostication in pulmonary embolism (PE) is crucial due to the broad range of clinical severity, and biomarkers such as arterial lactate are considered helpful markers for illness severity. Venous lactate ...
Shortcoming of serum B-cell maturation antigen measurement by enzyme-linked immunosorbent assay in one laboratory's experience: Unsatisfactory assay reproducibility [0.03%]
一种实验室经验中的血清B细胞成熟抗原酶联免疫吸附测定的不足：测定再现性不理想
Ian Cheong,Christopher Liang,Vipin Bhayana et al.
Ian Cheong et al.
Introduction: Serum protein electrophoresis and serum free light chain (SFLC) assays are standard methods for monitoring patients with multiple myeloma (MM). However, patients with non-secretory MM often require invasive ...