Chulaluck Kuptanon,Pawinee Innark,Kannikar Punnapum et al.
Chulaluck Kuptanon et al.
Objectives: Thailand expanded metabolic newborn screening (NBS) program to include inherited metabolic diseases (IMDs) using tandem mass spectrometry since 2022. Molecular testing has increasingly been used as a second-ti...
Evaluating prognostic performance for acute delta changes of high-sensitivity cardiac troponin T in emergency department patients [0.03%]
急诊患者高敏肌钙蛋白T急性变化的预后性能评估
Fang Wu,Tanzy Love,Xueya Cai et al.
Fang Wu et al.
Objectives: To evaluate the prognostic value of 0/1h and 0/3h high-sensitivity cardiac troponin T (hs-cTnT) delta values for 30-day and 1-year all-cause mortality among emergency department (ED) patients. ...
Outlook on ACADSB variants shaping metabolomic patterns and clinical outcomes - experience from a Central European country [0.03%]
ACADSB变异体对代谢模式和临床结局影响的展望——来自中欧国家的经验
Andrej Bandura,Ján Chandoga,Jerguš Vengríni et al.
Andrej Bandura et al.
Background: Short/branched-chain acyl-CoA dehydrogenase deficiency (SBCADD) is an autosomal recessive defect of L-isoleucine catabolism caused by pathogenic variants in the ACADSB gene. While early reports described neuro...
Elevated IL-27 and altered anti-inflammatory cytokine levels in SLE patients with end-stage renal disease [0.03%]
终末期肾病患者血清IL-27和抗炎细胞因子水平变化
Paria Bayati,Doaa Hussein Neamah,Yasser Bagheri et al.
Paria Bayati et al.
Objectives: IL-10, TGF-β, IL-4, IL-27, and EBI3 are cytokines that regulate inflammation, tissue repair, and fibrosis in the kidney and other organs. These cytokines may contribute to different aspects of chronic kidney ...
TUG1 and miR-145 as potential biomarkers associating hypothyroidism to cardiovascular risk [0.03%]
TUG1和miR-145作为甲状腺功能减退与心血管风险关联的潜在生物标志物
Tarek K Motawi,Olfat G Shaker,Haidy Saied et al.
Tarek K Motawi et al.
Objectives: RNA based epigenetic modifications and their relations with chronic diseases have been widely studied. The current study aimed to determine the role of long noncoding RNA (lncRNA) TUG1 and microRNA 145 (miR-14...
Interference and failure: The challenge of high-concentration IgM monoclonal protein in capillary zone electrophoresis [0.03%]
干扰与失败：高浓度IgM单克隆蛋白毛细管区带电泳检测挑战
Yanhua Zhao,Minjie Zhang,Wei Gan
Yanhua Zhao
Background: Capillary zone electrophoresis (CZE) is a standard method for serum protein separation, but its performance can be compromised by IgM monoclonal proteins, leading to false-negative results. ...
Indirect reference intervals for thyroid function tests: refineR, RefLim and effects of pathological test results [0.03%]
甲状腺功能检测的间接参考区间：refineR、RefLim以及病理检验结果的影响
Finn Erik Aas,Alexander Bauer Westbye,Magnus A R Husøy et al.
Finn Erik Aas et al.
Background: Biochemical tests with reference intervals (RIs) are extensively used in medicine. RIs should reflect the population tested, and indirect methods for RI construction are increasingly used. Thyroid function tes...
Best practice recommendations for laboratory analysis and reporting of cerebrospinal fluid oligoclonal banding and associated tests for multiple sclerosis (MS): a consensus report from the harmonized CSF analysis for MS investigation (hCAMI) subcommittee of the Canadian society of clinical chemists (CSCC) [0.03%]
加拿大临床化学家协会(CSCC)关于多发性硬化症相关脑脊液检查的标准化分析和报告的最佳实践共识声明：来自CSCC多发性硬化症脑脊液联合研究小组（hCAMI）亚委员会的共识报告
Victoria Higgins,Michelle L Parker,Basma Ahmed et al.
Victoria Higgins et al.
Cerebrospinal fluid (CSF) oligoclonal banding (OCB) analysis is an important component in the diagnosis of multiple sclerosis (MS). In the 2024 McDonald Criteria for MS diagnosis, CSF-specific OCB can support MS diagnosis, including in thos...
Practice Guideline
Clinical biochemistry. 2026 Feb 13:142:111098. DOI:10.1016/j.clinbiochem.2026.111098 2026
Choosing wisely Canada recommendations for point of care testing utilization in the acute care setting: Expert-based Delphi consensus from the Canadian Society of Clinical Chemists [0.03%]
加拿大POCT专家组基于德尔菲共识提出的明智选择：加拿大临床化学家协会在急性护理环境中使用的POCT建议
Sukhbir Kaur,Saranya Arnoldo,Jennifer Taher et al.
Sukhbir Kaur et al.
Introduction: Point of care testing (POCT) offers a broader selection of clinical testing outside of a central laboratory due to its many benefits, such as accessibility and rapid turn-around-time. However, it does have d...
Practice Guideline
Clinical biochemistry. 2026 Feb 13:111100. DOI:10.1016/j.clinbiochem.2026.111100 2026