Less is more: minimum sample volume for the free phenytoin assay on the Roche Cobas c503 analyzer [0.03%]
最小化样本体积检测RocheCobas_c503_分析仪中毒药苯妥英的自由浓度性能優良
Ka Keung Chan,Sharlene Butler,Y Victoria Zhang
Ka Keung Chan
Rasmus Bo Hasselbalch,Nina Strandkjær,Jonas Kristensen et al.
Rasmus Bo Hasselbalch et al.
Background: The 99th percentile of cardiac troponin (cTn) among healthy individuals is the diagnostic cutoff for myocardial infarction. This study investigates the effect of age on the 99th percentile of cTn among healthy...
Christopher Farnsworth,Jianbo Yang,Robert Maynard et al.
Christopher Farnsworth et al.
Introduction: Hemolysis causes falsely elevated potassium results and if undetected, can lead to misidentification of hypokalemia or hyperkalemia causing delayed or inappropriate treatment. The prevalence of hemolysis in ...
Circulating plasma RNY1 as a potential biomarker of breast cancer: a case-control study [0.03%]
血浆circRNY1作为乳腺癌潜在标志物的病例对照研究
Raghda Saad Zaghloul Taleb,Pacint Elsayed Moez,Marwa Ibrahim Khedr et al.
Raghda Saad Zaghloul Taleb et al.
Background: Breast cancer (BC) is the most common cancer in women globally, with early detection playing a crucial role in improving treatment outcomes and survival rates. There is an urgent need for novel biomarkers to a...
Improving laboratory stewardship through benchmarking: A focus on thyroid function tests ordering [0.03%]
利用实验室数据开展甲状腺功能检测合理用药提升项目
Ka Keung Chan,Suhhyun Kim,Patrick C Mathias et al.
Ka Keung Chan et al.
Objectives: Thyroid function tests, particularly thyroid-stimulating hormone (TSH) and free thyroxine (fT4), are among the most frequently ordered laboratory tests. This study evaluates longitudinal trends in thyroid test...
Implementing minimal request intervals for laboratory tests: a utilization management study across eight hospitals in South Iran [0.03%]
南伊朗八家医院实验室检验最小请求间隔的实施与使用管理研究
Babak Shirazi Yeganeh,Zahra Rabet,Zahra Afsar et al.
Babak Shirazi Yeganeh et al.
Introduction: Effective utilization management in medical laboratories is a challenge. To address this, strategies such as clinical guidelines, minimum requesting intervals (MRIs), and test request limits integrated into ...
Rasmus Søgaard Hansen,Peter H Nissen,Julie Brogaard Larsen et al.
Rasmus Søgaard Hansen et al.
Objective: Describe challenges in diagnosing protein S deficiency. Methods: A women in her late 20 s and pregnant in third trimester (G...
Choosing Wisely Canada recommendations for clinical biochemistry: test ordering for sustainable and high-quality patient care [0.03%]
加拿大临床生化领域明智选择建议：为了可持续和高质量的患者护理而订购检测项目
Daniel R Beriault,Yu Chen,Paul Yip et al.
Daniel R Beriault et al.
Laboratory Medicine is growing at a rapid rate in both the breadth of unique tests and the total number of tests performed per year. Inappropriate overutilization of laboratory tests can lead to patient harm, excessive environmental waste a...
Wide-range and high-throughput quantification of anamorelin in human plasma using ultra-high-performance liquid chromatography coupled to tandem mass spectrometry [0.03%]
一种用于人血浆中Anamorelin超宽范围高通量定量的UPLC-MS/MS方法
Takahiro Sumimoto,Ryota Tanaka,Ayaka Sato et al.
Takahiro Sumimoto et al.
Objective: Cancer cachexia is characterized by weight loss, muscle mass loss, and reduced food intake. Anamorelin is a ghrelin receptor agonist approved for the treatment of cancer cachexia. In this study, we established ...
The comparison of miRNA expression levels in Type 2 diabetes and diabetic peripheral neuropathy patients [0.03%]
2型糖尿病与糖尿病外周神经病变患者中miRNA表达水平的比较分析
Aleyna Ayaz,Sibel Kuras,Bekir Erdogan et al.
Aleyna Ayaz et al.
Objectives: We aimed to investigate the correlation between miRNA expression levels in patients with type 2 diabetes mellitus (T2DM) and diabetic peripheral neuropathy (DPN) and determine their potential functions in DPN....