In C57BL/6J mice, weight loss in previously obese mice reduced bone mass and shifted the cortical bone metabolome [0.03%]
在C57BL/6J小鼠中,先前肥胖小鼠的体重减轻减少了骨密度并改变了皮质骨代谢组
Carolyn Chlebek,Casey McAndrews,Benjamin Aaronson et al.
Carolyn Chlebek et al.
Obesity is linked to increased fracture risk. Despite the negative effects of weight loss on the skeleton, patients with obesity are advised to lose weight via calorie restriction. Obesity and weight loss individually alter both whole-body ...
Response to the letter to the editor: "Comparative effectiveness of romosozumab versus teriparatide for fracture prevention: A new-user, active comparator design" [0.03%]
关于致编辑信函“比较研究Romosozumab与特立帕肽在骨折预防方面的有效性:一项新用户,活性对照设计”的回复
Ryoji Tominaga,Tatsuyoshi Ikenoue,Ryosuke Ishii et al.
Ryoji Tominaga et al.
A review of bone fracture healing modelling: from mechanobiological theory to personalized rehabilitation protocols [0.03%]
骨骼骨折愈合模型研究综述:从力学生物学理论到个性化康复方案
Lunjian Li,Minoo Patel,Lihai Zhang
Lunjian Li
Despite standard rehabilitation protocols, many patients still suffer from limited mobility, delayed union, or even non-union. This underscores the need for personalized rehabilitation protocols. Fracture healing is a dynamic process govern...
Regional analysis of subtrochanteric femoral cortical bone microstructure in healthy adults using double-echo ultrashort echo time magnetic resonance imaging [0.03%]
健康成人股骨粗隆下皮质骨微结构的区域分析——双回波超短回波时间磁共振成像研究
Yitong Li,Zheng Ran,Bowen Hou et al.
Yitong Li et al.
Objective: The subtrochanteric region of the femur is a common site for atypical femoral fracture (AFF), and the research of its cortical bone microstructure is important but currently lacking. Conventional whole-bone ana...
Familial determinants of bone health parameters- a dual X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT)-based parent and offspring study in rural Indian children [0.03%]
基于双能X线吸收法(DXA)和周围定量计算机断层扫描(pQCT)的印度农村儿童及其父母骨健康参数的家庭决定因素研究
Sharvani Patil,Nikhil Shah,Alex Ireland et al.
Sharvani Patil et al.
Background: Skeletal health relationships in children and parents have been investigated over the years with contradictory results and often without accounting for the influence of modifiable factors. Limited data exist o...
Medication-related osteonecrosis of the jaw following osteoporosis therapy: A real-world retrospective cohort study using the TriNetX global collaborative network [0.03%]
绝经后妇女抗骨质疏松药物治疗相关的颌骨坏死的回顾性队列研究:TriNetX 全球协作网络真实世界数据研究
Tse-Yu Chen,Ya-Lian Deng,I-Chieh Chen et al.
Tse-Yu Chen et al.
Introduction: Medication-related osteonecrosis of the jaw (MRONJ) was first reported in cancer patients receiving high-dose intravenous bisphosphonates and later linked to other anti-resorptive agents such as denosumab an...
The association between body roundness index and lumbar marrow fat content in postmenopausal women [0.03%]
体脂分布指数与绝经后女性腰椎骨髓脂肪含量的相关性研究
Peng Luo,Zeyang Miao,Mengyao Guo et al.
Peng Luo et al.
Objective: To investigate the relationship between body roundness index (BRI) and lumbar marrow proton density fat fraction (PDFF) in postmenopausal women, with emphasis on potential nonlinear associations. ...
Anisotropic mechanical characterization of trabecular bone with linear and non-linear voxel-based finite elements from photon-counting CT [0.03%]
基于光子计数CT的线性和非线性体素有限元的三维各向异性骨小梁力学表征
Jilmen Quintiens,Thomas Morren,Walter Coudyzer et al.
Jilmen Quintiens et al.
Bone structural and mechanical properties predict fragility fractures, but unexplained variance remains. A better quantification of the anisotropic nature of bone, and an improved model-based prediction of bone failure load could fill in th...
Comparing bone and muscle parameters in community-dwelling older adults with obesity, with or without type 2 diabetes mellitus [0.03%]
社区中肥胖并伴有或不伴2型糖尿病老年人的骨骼和肌肉参数比较
Costas Glavas,Jakub Mesinovic,Peter R Ebeling et al.
Costas Glavas et al.
Background: Obesity is common in type 2 diabetes mellitus (T2DM) and is associated with lower fracture risk. However, older adults with T2DM have higher fracture rates, suggesting distinct effects of T2DM on musculoskelet...
Biochemical osteomalacia reaffirmed by signs and symptoms and perinatal outcome. A prospective cohort study of women in Sweden [0.03%]
生化性骨软化的确证、临床表现及围产期结局:瑞典妇女的前瞻性队列研究
Kalliokoski Paul,Thomas Torstensson,Kristiansson Per
Kalliokoski Paul
Background: Vitamin D deficiency-induced osteomalacia remains underexplored, despite the substantial migration to northern sun-deprived latitudes. In women, osteomalacia may impair smooth and striated muscle function and ...