Frida Igland Nissen,Camilla Andreasen,Tove Tveitan Borgen et al.
Frida Igland Nissen et al.
Purpose: Fracture risk is most frequently assessed using Dual X-ray absorptiometry to measure areal bone mineral density (aBMD) and using the Fracture Risk Assessment Tool (FRAX). However, these approaches have limitation...
Total body bone mineral density and severe COVID-19: A Mendelian randomization analysis in five age strata [0.03%]
全身骨矿物质密度与重度COVID-19之间的关系：五个年龄段的孟德尔随机化分析
Shu Ran,Shuyu Zhang,Huiting Chen et al.
Shu Ran et al.
Once daily calcium (1000 mg) and vitamin D (1000 IU) supplementation during military training prevents increases in biochemical markers of bone resorption but does not affect tibial microarchitecture in Army recruits [0.03%]
每日一次钙（1000毫克）和维生素D（1000国际单位）的补充可以防止军事训练中骨吸收生物化学标记物的增加，但对新兵的胫骨微结构没有影响
Erin Gaffney-Stomberg,Julie M Hughes,Katelyn I Guerriere et al.
Erin Gaffney-Stomberg et al.
Basic combat training (BCT) is a period of novel physical training including load carriage resulting in higher risk of stress fracture compared to any other time during military service. Prior trials reported a 20% reduction in stress fract...
Randomized Controlled Trial
Bone. 2022 Feb:155:116269. DOI:10.1016/j.bone.2021.116269 2022
Associations between parameters of peripheral quantitative computed tomography and bone material strength index [0.03%]
骨质外围定量计算机断层摄影各参数与骨骼物质强度指数之间的关系
Kara L Holloway-Kew,Pamela Rufus-Membere,Kara B Anderson et al.
Kara L Holloway-Kew et al.
Background: Bone material strength index (BMSi) is measured in vivo using impact microindentation (IMI). However, the associations between BMSi and other bone measures are not clear. This study investigated whether bone p...
Mouse LGR6 regulates osteogenesis in vitro and in vivo through differential ligand use [0.03%]
LGR6通过差异配体使用在体内和体外调节小鼠的骨形成
Vikram Khedgikar,Julia F Charles,Jessica A Lehoczky
Vikram Khedgikar
Leucine-rich repeat containing G-protein-coupled receptor 6 (LGR6) is a marker of osteoprogenitor cells and is dynamically expressed during in vitro osteodifferentation of mouse and human mesenchymal stem cells (MSCs). While the Lgr6 genomi...
Assessing bone maturity: Compositional and mechanical properties of rib cortical bone at different ages [0.03%]
评估骨成熟度：不同年龄段肋皮质骨的组成和力学性能
Andrea Bonicelli,Elena F Kranioti,Bledar Xhemali et al.
Andrea Bonicelli et al.
Understanding what maturity entails for bone, when it arrives, and its pre- and post-maturity traits and properties are very important for understanding its evolution and physiology. There is a clear but fine distinction between the chronol...
Bin He,Jinqiu Zhao,Muzi Zhang et al.
Bin He et al.
Circulating adiponectin has some association with the risk of osteoporosis and cancers, but their causal relationships remains elusive. Mendelian randomization (MR) study was used to explore the causal roles of circulating adiponectin in os...
Characterization of mouse Bmp5 regulatory injury element in zebrafish wound models [0.03%]
斑马鱼伤口模型中鼠Bmp5调控损伤元件的特征分析
Ian S Heller,Catherine A Guenther,Ana M Meireles et al.
Ian S Heller et al.
Many key signaling molecules used to build tissues during embryonic development are re-activated at injury sites to stimulate tissue regeneration and repair. Bone morphogenetic proteins provide a classic example, but the mechanisms that lea...
CF101 alleviates OA progression and inhibits the inflammatory process via the AMP/ATP/AMPK/mTOR axis [0.03%]
CF101通过AMP/ATP/AMPK/mTOR轴缓解OA进展并抑制炎症过程
Lin Liu,Hui Bai,Guangming Jiao et al.
Lin Liu et al.
CF101 (IB-MECA) is an adenosine A3 receptor agonist that has anti-inflammatory and pain-relieving properties. Adenosine A3 receptor activation can delay the process of Osteoarthritis(OA) and prevent the occurrence of OA. However, the mechan...