Cerebellar Subregional Atrophy in Relapsing-Remitting Multiple Sclerosis: Stage-dependent Dynamics and Pharmacological Modulation [0.03%]
复发性多发性硬化的小脑亚区萎缩：阶段依赖的动力学和药理调节
Xiaohui Zhang,Jinzhou Feng,Zhiwei Zhang et al.
Xiaohui Zhang et al.
Background: Cerebellar atrophy is increasingly recognized as an important pathological feature of multiple sclerosis (MS). However, the specific patterns at different stages and their alteration by disease-modifying thera...
Microstructural White Matter Impairments in Chronic Fatigue Syndrome: Evidence of Segmental Injury in the Cingulum Bundle [0.03%]
慢性疲劳综合征中微结构白质损伤：脑环束分节损伤的证据
Kang Wu,Ziyao Wu,Sitong Feng et al.
Kang Wu et al.
Background: Chronic fatigue syndrome (CFS) is a neurological disorder characterized by persistent fatigue. Previous studies have shown structural and functional brain alterations in CFS patients. However, how chronic fati...
Sodium acetate and sodium butyrate ameliorate postoperative cognitive dysfunction in aged rats by suppressing inflammation and ferroptosis via inhibition of the cGAS-STING signaling pathway [0.03%]
乙酸钠和丁酸钠通过抑制cGAS-STING信号通路来改善老年大鼠术后认知功能障碍
Kai-Hui Zeng,Li-Ping Yu,Zhen Chen et al.
Kai-Hui Zeng et al.
Background: Postoperative cognitive dysfunction (POCD) is a common neurocognitive complication in elderly patients following surgery. Short-chain fatty acids (SCFAs), including acetate and butyrate, exert anti-inflammator...
CAF-derived Exosomes Promote the Proliferation and Invasion of Pituitary Adenoma Cells via miR-184 Transfer [0.03%]
CAFs来源的外泌体通过miR-184转移促进垂体腺瘤细胞增殖和侵袭
Qiu Du,Zhiyong Chen,Weiyu Zhang et al.
Qiu Du et al.
Pituitary adenomas (PAs) are common intracranial tumors whose mass effects and endocrine dysfunction pose serious threats to patient health. However, the mechanisms underlying their progression, particularly the role of the tumor microenvir...
Nelson Cortes,Capucine Mandel,Lamyae Ikan et al.
Nelson Cortes et al.
The pulvinar is a higher-order thalamic hub with widespread cortico-cortical and cortico-limbic connectivity. Here we synthesize evidence that pulvinar circuits shape perception and cognition via three computations: (i) precision-weighted g...
Brain Network Localization of High-Frequency Heart Rate Variability: A Meta-Analysis and Coordinate-Based Network Mapping Approach [0.03%]
基于坐标的功能连接脑网络定位高频心率变异性的 meta 分析及网络映射研究
Yifan Fang,Tianyi Li,Wenwen Liang et al.
Yifan Fang et al.
This study investigated the neural mechanisms behind high-frequency heart rate variability (HF-HRV), a marker of cardiac parasympathetic tone, which is crucial for understanding the interplay between physiological and emotional regulation. ...
MCU knockdown mitigates post-stroke neuroinflammation through SLC33A1-mediated reduction of NR4A1 acetylation [0.03%]
MCU敲低通过SLC33A1介导的NR4A1乙酰化降低减轻卒中后神经炎症
Zhou Zhou,Lijuan Liu,Yicong Zhou et al.
Zhou Zhou et al.
Post-stroke neuroinflammation remains a critical contributor to disease progression and recovery. Building on our prior finding that knockdown of the mitochondrial calcium uniporter (MCU) confers protection against ischemic injury, and guid...
Abnormal dynamic connectivity patterns in self-limited epilepsy with centrotemporal spikes [0.03%]
中心中颞棘波自限性癫痫的异常动态功能连接模式
Xu Chen,Linfeng Song,Jiaren Zhang et al.
Xu Chen et al.
Objective: To characterize the dynamic functional network connectivity (dFNC) patterns in children with self-limited epilepsy with centrotemporal spikes (SeLECTS) and to uncover potential abnormalities in neural regulatio...
Forced and voluntary exercise exert differential neuroprotective effects in cerebral ischemia-reperfusion injury by inhibiting neutrophil infiltration and blood-brain barrier disruption [0.03%]
强制运动和自主运动通过抑制中性粒细胞浸润和血脑屏障破坏对脑缺血再灌注损伤发挥不同的神经保护作用
Manyao Zou,Jie Wang,Long Yu et al.
Manyao Zou et al.
Ischemic stroke is associated with high disability rates, underscoring the urgent need for effective rehabilitation strategies. While exercise rehabilitation promotes functional recovery, the differential therapeutic effects of distinct exe...
Alterations in dynamic regional homogeneity and functional connectivity in lung cancer patients with bone metastasis pain [0.03%]
肺癌骨转移患者疼痛的动态局部一致性及功能连接改变研究
Yu Tang,Tan Cheng,Lin Tang et al.
Yu Tang et al.
Background: Although previous neuroimaging studies have characterized static brain activity in bone metastasis pain (BMP), its dynamic functional properties remain largely unexplored. This study aimed to investigate the d...