Water-filtered Infrared A and visible light (wIRA/VIS) treatment reduces Chlamydia caviae-induced ocular inflammation and infectious load in a Guinea pig model of inclusion conjunctivitis [0.03%]
水滤过型红外A和可见光(wIRA/VIS)治疗减少豚鼠 inclusion conjunctivitis 模型中沙眼衣原体感染所致的结膜炎和病原体载量
Aleksandra Inic-Kanada,Marijana Stojanovic,Radmila Miljkovic et al.
Aleksandra Inic-Kanada et al.
Trachoma is a devastating neglected tropical disease caused by Chlamydia trachomatis and the leading global cause of infectious blindness. Although antibiotic treatment against trachoma is efficient (SAFE strategy), additional affordable th...
A ROS responsive nanomedicine with enhanced photodynamic therapy via dual mechanisms: GSH depletion and biosynthesis inhibition [0.03%]
一种ROS响应型纳米药物通过双重机制(GSH耗尽和生物合成抑制)增强光动力疗法
Jinhui Hu,Ting Wang,Lin Zhou et al.
Jinhui Hu et al.
Reduced glutathione (GSH, containing sulfydryl) inside cancer cells strongly consumes reactive oxygen species (ROS) in photodynamic therapy (PDT) process to reduce PDT effect. Thiol-ene click reaction is a classic method to couple sulfydryl...
Exoenzyme C3 transferase lowers actin cytoskeleton dynamics, genomic stability and survival of malignant melanoma cells under UV-light stress [0.03%]
外源酶C3转移酶降低UV光压力下恶性黑色素瘤细胞中肌动蛋白细胞皮层动力学、基因组稳定性和存活率
Yuli T Magalhaes,Giovanna D Cardella,Fabio L Forti
Yuli T Magalhaes
Actin cytoskeleton remodeling is the major motor of cytoskeleton dynamics driving tumor cell adhesion, migration and invasion. The typical RhoA, RhoB and RhoC GTPases are the main regulators of actin cytoskeleton dynamics. The C3 exoenzyme ...
Biogeochemical and photobiological responses of subarctic lakes to UV radiation [0.03%]
紫外线辐射对亚北极湖泊生物地球化学和光生物学的响应
Liisa Nevalainen,Marttiina V Rantala,E Henriikka Kivilä et al.
Liisa Nevalainen et al.
Solar ultraviolet radiation (UV) induces photodegradation of optically and functionally important organic compounds in lakes and may negatively impact aquatic biota. We disentangled UV impacts on dissolved organic matter (DOM) transformatio...
Insulin-like growth factor-I rescue of primary keratinocytes from pre- and post-ultraviolet B radiation effects [0.03%]
胰岛素样生长因子-I对紫外线辐射前后原代角质形成细胞的保护作用
Melisa J Andrade,Kapaettu Satyamoorthy,Zee Upton et al.
Melisa J Andrade et al.
Ultraviolet B radiation (UVBR) induces the formation of photolesions in epidermal keratinocytes, potentially affecting cellular function and contributing towards malignant transformation. Insulin-like growth factor-I (IGF-I) contributes to ...
A general framework for non-exponential delayed fluorescence and phosphorescence decay analysis, illustrated on Protoporphyrin IX [0.03%]
以原卟啉IX为例的非指数衰减延迟荧光和磷光谱分析通用框架
Gauthier Croizat,Aurélien Gregor,Emmanuel Gerelli et al.
Gauthier Croizat et al.
Delayed fluorescence (DF) is a long-lived luminescence process used in a variety of applications ranging from oxygen sensing in biological tissues to organic Light Emitting Diodes. In common cases, DF results from the de-excitation of the f...
Anticancer pentamethinium salt is a potent photosensitizer inducing mitochondrial disintegration and apoptosis upon red light illumination [0.03%]
一种抗肿瘤五甲基
Radovan Krejcir,Tomas Briza,Martin Sterba et al.
Radovan Krejcir et al.
Despite progress in the development and application of novel therapeutic agents, cancer remains a major cause of death worldwide. Therefore, there is a need for new approaches to increase therapeutic options and efficiency. The metabolism o...
Single and repeated low-dose UVB radiation exposures affect the visual system [0.03%]
单次和反复低剂量UVB照射会影响视觉系统
Valmor Vinicius Araujo Vaz,Leandra Jardim da Silva,Márcio Alberto Geihs et al.
Valmor Vinicius Araujo Vaz et al.
The visual system is an important biological indicator of effects induced by ultraviolet (UV) radiation. However, research has extensively investigated the effects of high-dose UV radiation in a single exposure, thus, the differential of th...
Characterization of the fluorescence intensity and color tonality in the exoskeleton of scorpions [0.03%]
用于描述蝎子外骨骼荧光强度和色调特征的研究
Daniel López-Cabrera,Gabriel Ramos-Ortiz,Edmundo González-Santillán et al.
Daniel López-Cabrera et al.
Scorpions are a mesodiverse and nocturnal group of arachnids inhabiting most biomes worldwide. Different species of scorpions have divergent adaptations to the substrate they live in, but most of them share an intriguing characteristic: the...
Chemical features of the photosensitizers new methylene blue N and S137 influence their subcellular localization and photoinactivation efficiency in Candida albicans [0.03%]
新型亚甲蓝N和S137的化学特性影响其在白色念珠菌中的亚细胞定位及光灭活效率
Gabriela Braga Rodrigues,Guilherme Thomaz Pereira Brancini,Sérgio Akira Uyemura et al.
Gabriela Braga Rodrigues et al.
Antimicrobial photodynamic treatment (APDT) has emerged as an effective therapy against pathogenic fungi with both acquired and intrinsic resistance to commonly used antifungal agents. Success of APDT depends on the availability of effectiv...