Highlights on the imaging (nuclear/fluorescence) and phototherapeutic potential of a tri-functional chlorophyll-a analog with no significant toxicity in mice and rats [0.03%]
关于具有光疗潜能的三功能叶绿素a类似物的成像(核/荧光)研究及其在大鼠和小鼠体内无显著毒性的亮点分析
Avinash Srivatsan,Paula Pera,Penny Joshi et al.
Avinash Srivatsan et al.
Herein we report the positron emission tomography (PET) imaging potential of a 124I-labeled radiopharmaceutical (PET-ONCO). In tumored mice, it shows high uptake in a variety of tumors: brain (GL261, U87), Colon (Colon26), lung (Lewis lung)...
In-vivo usefulness of optical coherence tomography in atrophic-erosive oral lichen planus: Comparison between histopathological and ultrastructural findings [0.03%]
萎缩性口腔扁平苔藓的活体光学相干断层扫描作用:组织病理学与超微结构的研究比较
Alessio Gambino,Marco Cabras,Adriana Cafaro et al.
Alessio Gambino et al.
Oral lichen planus (OLP) is a common premalignant chronic inflammatory disorder. Optical Coherence Tomography (OCT) provides a real-time, non-invasive, and in-situ optical signature using light of varying wavelengths to examine tissue. Aim ...
Co-delivery of IR-768 and daunorubicin using mPEG-b-PLGA micelles for synergistic enhancement of combination therapy of melanoma [0.03%]
使用mPEG-b-PLGA胶束共递送IR-768和柔红霉素以协同提高黑色素瘤组合治疗的效果
Katarzyna Tokarska,Łukasz Lamch,Beata Piechota et al.
Katarzyna Tokarska et al.
Malignant melanoma is an emerging problem worldwide due to the high degree of lethalness. Its aggressiveness and the ability to metastasize along with the heterogeneity at the molecular and cellular levels, limit the overall therapeutic eff...
Circadian movement behaviours and metabolism differences of the Pacific abalone Haliotis discus hannai [0.03%]
间日蝶蛾螺的运动行为和代谢差异及节律研究
Xiaolong Gao,Xuan Luo,Weiwei You et al.
Xiaolong Gao et al.
Circadian rhythm is the most important and universal biological rhythm in marine organisms. In this research, the movement behaviour of abalone (Haliotis discus hannai) was continuously monitored under a light cycle of 12 L:12D. It was foun...
Nucleic acid binding mechanism of flavone derivative, riviciclib: Structural analysis to unveil anticancer potential [0.03%]
黄酮衍生物Ravicilib的核酸结合机制:结构分析揭示抗癌潜力
Bhumika Ray,Ranjana Mehrotra
Bhumika Ray
Despite burgeoned knowledge about the origin, growth, tissue interactions, and spread of cancer in recent years, the functional complexity and unique survival ability of cancer cells still make it difficult to target them. Riviciclib is a s...
Light-based technologies for management of COVID-19 pandemic crisis [0.03%]
基于光的技术在COVID-19疫情期间的应用管理
Caetano P Sabino,Anthony R Ball,Mauricio S Baptista et al.
Caetano P Sabino et al.
The global dissemination of the novel coronavirus disease (COVID-19) has accelerated the need for the implementation of effective antimicrobial strategies to target the causative agent SARS-CoV-2. Light-based technologies have a demonstrabl...
Developmental effects of constant light on circadian behaviour and gene expressions in zebra finches: Insights into mechanisms of metabolic adaptation to aperiodic environment in diurnal animals [0.03%]
恒定光照对斑胸草雀的生物钟行为和基因表达的影响及其在日行性动物代谢适应无周期环境中的机制研究
Abhilash Prabhat,Indu Malik,Neelu Anand Jha et al.
Abhilash Prabhat et al.
A most crucial feature of biological adaptation is the maintenance of a close temporal relationship of behaviour and physiology with prevailing 24-h light-dark environment, which is rapidly changing with increasing nighttime illumination. T...
Laser irradiated phenothiazines: New potential treatment for COVID-19 explored by molecular docking [0.03%]
激光照射的吩噻嗪类药物:通过分子对接探索治疗COVID-19的新潜力方法
Ana-Maria Udrea,Speranta Avram,Simona Nistorescu et al.
Ana-Maria Udrea et al.
The worldwide infection with the new Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) demands urgently new potent treatment(s). In this study we predict, using molecular docking, the binding affinity of 15 phenothiazines (antihi...
Circadian rhythm in photoperiodic expressions of GnRH-I and GnIH regulating seasonal reproduction in the Eurasian tree sparrow, Passer montanus [0.03%]
光周期对欧亚树麻雀季节性繁殖的调控因子GnRH-I和GnIH的生物钟节奏表达规律研究
Anand S Dixit,Sanborlang Byrsat,Namram Sushindrajit Singh
Anand S Dixit
The present study investigates the involvement of circadian rhythm in photoperiodic expressions of GnRH-I and GnIH in the hypothalamus controlling seasonal reproduction in the Eurasian tree sparrow (Passer montanus). Groups of photosensitiv...
Near-infrared NIR irradiation and sodium hypochlorite: An efficacious association to counteract the Enterococcus faecalis biofilm in endodontic infections [0.03%]
近红外(NIR)照射结合次氯酸钠有效对抗根管治疗感染中的粪肠球菌生物膜
Simonetta DErcole,Paola Di Fermo,Mara Di Giulio et al.
Simonetta DErcole et al.
New strategies are necessary for the prevention of endodontic infections caused by Enterococcus faecalis, a common resistant pathogen and biofilm producer. Aim of the present study was to compare the effects of Near-Infrared (NIR) Light-Emi...