A photoinduced nuclear translocation of thiophene derivative for selective chemotherapy [0.03%]
一种噻吩衍生物的光控核转位选择性化疗研究
Dat Thanh Dinh,Yi-Liang Liou,Tzong-Shiun Li et al.
Dat Thanh Dinh et al.
In this study, a novel thiophene-based small organic molecule, 2,5-bis(2-(N-butylpyridinium-4-yl)vinyl)-thiophene diiodine (BBT), was prepared. BBT not only presented selective dark/photo dual cell toxicity to cancer cells but also acted as...
Femtosecond laser-induced myocardial incision: Preclinical study towards new tools for precision cardiac surgery [0.03%]
飞秒激光诱导心肌切割：面向精准心脏外科手术的新工具的临床前研究
Ang Liu,Tong Xia,Siyuan Cao et al.
Ang Liu et al.
Background: Advanced precise laser techniques for myocardial tissue removal still need to be further explored. Femtosecond laser technology, renowned for its high precision and relatively minor collateral damage in biolog...
Therapeutic potential of near-infrared polychromatic light in hyperglycemic human cell models: Toward improved diabetic wound healing [0.03%]
近红外多色光在高血糖人细胞模型中的治疗潜力：改善糖尿病伤口愈合的新方法
Simge Çıtak Demirez,Tülay Selin Erkut,Anıl Sera Çakmak et al.
Simge Çıtak Demirez et al.
Diabetic ulcers are a serious complication of diabetes, often leading to reduced quality of life and, in many cases, limb amputation. These ulcers are characterized by impaired wound healing, primarily due to hyperglycemia-induced inflammat...
Natural-synthetic hybrid nanoparticles: Polydopamine-Phycocyanin composites for enhanced antibacterial phototherapy against bacterial pathogens [0.03%]
基于多巴胺和藻蓝蛋白的天然合成杂化纳米颗粒抗菌光疗研究
Armin Fakouri,Matin Mahmoudifard,Nahid Ghorbani et al.
Armin Fakouri et al.
The rapid rise of antibiotic-resistant bacterial infections demands innovative, non-antibiotic strategies to combat pathogens without driving further resistance. In this study, we developed polydopamine-coated phycocyanin nanoparticles (PDA...
A hydroxyl coumarin-chalcone-based fluorescent probe for sensing copper ions in plant and living cells [0.03%]
一种羟基香豆素查尔酮衍生物荧光探针用于活细胞和植物中铜离子的检测
Keyi Li,Yan Huang,Yatong Sun et al.
Keyi Li et al.
Copper ions are essential trace elements for living organisms. However, its excessive levels in the liver and kidneys may lead to severe health issues. Therefore, developing effective fluorescent probes for detecting copper ions is crucial....
Photobiomodulation mediates endoplasmic reticulum-mitochondria contact and ameliorates lipotoxicity in MASLD via Mfn2 upregulation [0.03%]
光生物调制通过上调Mfn2介导内质网-线粒体接触从而改善MASLD中的脂毒性
Zhixuan Jiang,Shan Wu,Shengzhe Zhou et al.
Zhixuan Jiang et al.
The disruption of mitochondria associated membranes (MAMs) is involved in the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD) by modulating endoplasmic reticulum stress (ERS) and mitochondrial malfunction in...
Enhanced photodynamic therapy with riboflavin@ dual minerals doped hydroxyapatite nanoparticles: A promising in vitro approach for bladder cancer [0.03%]
富含核黄素的双重矿物掺杂的羟基磷灰石纳米颗粒增强光动力疗法：体外治疗膀胱癌的一种前景疗法
Jinhua Wu,Dapeng Zong,Fei Li
Jinhua Wu
This research examines the efficacy of pure dual minerals (cerium and zinc) doped hydroxyapatite DHA and riboflavin (RFA)-coated DHA nanoparticles (NPs) (RFA@DHA NPs) in the treatment of bladder cancer. X-ray diffraction and Fourier-transfo...
Phthalocyanine-based nanosensitizers for enhanced sonodynamic therapy activity of hypoxic tumor with dual apoptosis/ferroptosis pathways [0.03%]
用于缺氧肿瘤增强型声动力学治疗的 phthalocyanine 纳米敏化剂及其诱导双重凋亡/铁死亡路径的研究
Xue-Yan Li,Jin Liu,Bi-Yuan Zheng et al.
Xue-Yan Li et al.
The development of efficient and versatile theranostic agents based on a single molecule for sonodynamic therapy (SDT) of hypoxic tumor remains a formidable challenge. Herein, we present a spatiotemporally controllable oxygen-releasing nano...
Photobiomodulation mitigates DHT-induced apoptosis in dermal papilla cells via mitochondrial rescue and Wnt/TGF-β/BMP signaling modulation [0.03%]
光生物调节通过线粒体救援和Wnt/TGF-β/BMP信号传导调制缓解二氢睾酮引起的乳头细胞凋亡
Yi Ren,Xiaojing Miao,Hui Jiang et al.
Yi Ren et al.
Current therapeutic interventions for androgenetic alopecia (AGA) are hindered by limited efficacy and adverse side effects. Photobiomodulation (PBM) has emerged as a promising non-invasive alternative, demonstrating preliminary potential f...
Prolonged DNA damage at suberythemal UV dose - Dependency on skin type and age [0.03%]
亚红斑量紫外线引起DNA损伤的持续存在与皮肤类型和年龄的关系
Daniela F Zamudio Díaz,Johannes Schleusener,Victor Hugo Pacagnelli Infante et al.
Daniela F Zamudio Díaz et al.
Ultraviolet radiation (UVR) is the primary risk factor for skin cancer, inducing DNA damage such as cyclobutane pyrimidine dimers (CPD) and pyrimidine-pyrimidone (6-4) photoproducts. DNA repair is influenced by age and skin type. Aging redu...