Synthesis and photophysical properties of a chlorin conjugate with a photoswitchable local anesthetic [0.03%]
一种含光控局麻药部分的胆绿素衍生物的合成及其光物理性质研究
Dmitriy A Minakov,Anton E Egorov,Alexey N Noev et al.
Dmitriy A Minakov et al.
A conjugate of natural chlorin and azobenzene bound via a linker was synthesized, its stability and photophysical properties were studied. This conjugate can be proposed as a prototype of a dual-action photopharmacological agent, which acts...
Red and blue light differentially regulate carbon metabolism and stem elongation in soybean cultivars with contrasting lodging resistance under shade: A multi-omics perspective [0.03%]
红光和蓝光通过多组学视角差异调控大豆品种的碳代谢和茎伸长反应以应对遮阴应力导致的倒伏风险不同的研究
Chang Wang,Shuo Huang,Xulang Zhang et al.
Chang Wang et al.
This study employed soybean cultivars 'Henong 60' (lodging-resistant) and 'Heinong 48' (lodging-prone) to investigate the effects of red and blue light on plant height, stem chloroplast ultrastructure, cell wall composition, non-structural ...
Unlocking the potential of spectral LED lights in enhancing glandular trichome density and accumulation of bioactive specialized metabolites in spearmint [0.03%]
解码光谱LED灯在提高留兰香腺毛密度和生物活性专业化合物积累潜能方面的潜力
Dipanjali Chatterjee,Adinpunya Mitra
Dipanjali Chatterjee
Spearmint is a well-known aromatic plant recognized for its unique aroma, flavour, and bioactive properties. To ensure its year-round production in response to the growing market demand under rapidly changing climates, the implementation of...
Association between ultraviolet exposure and type 2 diabetes: Insights from the China Health and Retirement Longitudinal Study (CHARLS) [0.03%]
基于中国健康与退休纵向研究的紫外线暴露与2型糖尿病关系分析
Can Ming,Zhuoyu Liu,Wei Wu et al.
Can Ming et al.
Objective: To investigate the association between long-term exposure to ambient ultraviolet radiation (UVR) and the risk of developing type 2 diabetes (T2D). ...
Photosensitization and phototoxicity mechanism of diclofenac sodium (NSAID) under ambient UVR exposure [0.03%]
环境中紫外线暴露下氯诺昔康（NSAIDs）光敏和光毒机制研究
Gaurav Prajapati,Sunil Kumar Patel,Durgesh Mourya et al.
Gaurav Prajapati et al.
Diclofenac sodium (DS) is used for pain, inflammation and musculoskeletal disorders. Despite its absorption of UV radiation, the phototoxic potential and molecular mechanisms in keratinocytes under UVA and UVB exposures are largely unexplor...
Defining safe operational conditions for two-photon imaging with rhodamine B and SYTO 9 dual-staining [0.03%]
基于rhodamine B和SYTO 9双标体系的安全化两光子操作条件定义
Yong Seok Lee,Hyun Seok Ryu,Celine Abueva et al.
Yong Seok Lee et al.
Two-photon microscopy (TPM) frequently employs dual-staining techniques for simultaneous visualization of cellular structure and viability. Despite widespread use, the safety of combining Rhodamine B (RB) and SYTO 9 dyes under 920 nm excita...
Transcriptomic profiling of eyeless Drosophila reveals molecular network orchestrating response to blue light [0.03%]
无眼果蝇的转录组分析揭示了调控蓝色光响应分子网络
Jun Yang,Song Yujuan,Rujul Kumar et al.
Jun Yang et al.
In a modern society where artificial light sources rich in blue light (BL) are pervasive, concerns about the potential health impacts of BL on humans are growing. The damage BL causes to the human retina is well established, but its effects...
Experimental study on photodynamic therapy of CCA assisted by electrolytic oxygen supply based on black phosphorus nanocomposites [0.03%]
基于黑磷纳米复合材料的电解供氧增强型光动力疗法治疗胆管癌的实验研究
Xinqiang Wu,Xiaofeng Jiang,Zhaoyuan Liu et al.
Xinqiang Wu et al.
Cholangiocarcinoma (CCA) is the second most common malignant liver tumor after hepatocellular carcinoma. It is highly aggressive, and most patients are diagnosed at an advanced stage, losing the opportunity for surgical resection. What's wo...
Differential UVC radiation sensitivity in multidrug-resistant l1210 cells: Insights into p53 and Bcl-XL expression/function [0.03%]
多药耐药的l1210细胞中UVC辐射敏感性的差异：p53和Bcl-XL表达/功能的新见解
Lucia Pavlikova,Jakub Krepop,Zdena Sulova et al.
Lucia Pavlikova et al.
Multidrug-resistant (MDR) variants of L1210 cells, selected for resistance to vincristine (R) or doxorubicin (D), exhibit elevated ABCB1 (P-glycoprotein) expression but differ in UVC sensitivity. D cells resemble parental L1210 (S) cells, w...
Dual-functional fluorescence probe for revealing metabolism during cellular cuproptosis [0.03%]
用于揭示细胞铜死亡过程中代谢变化的双功能荧光探针
Junyan Ma,Mingtao Zhao,Dan Meng et al.
Junyan Ma et al.
Cuproptosis, a newly identified type of cell death induced by copper, is associated with intracellular oxidative stress, mitochondrial dysfunction and protein aggregation. This work presents the development of a red-emitting fluorescent pro...