Fiber-optic-guided near-infrared laser exposure induces depolarization of cultured primary sensory neurons and modifies biophysical properties of human Nav1.5 channels [0.03%]
光纤引导的近红外激光照射引起原代感觉神经元去极化并改变人类Nav1.5通道的生物物理性质
Florian Armăşescu,Bogdan Amuzescu,Roxana-Olimpia Gheorghe et al.
Florian Armăşescu et al.
Photobiomodulation, a therapeutic method promoting wound healing, reduction in inflammation, pain and apoptosis, was widely tested in neurological/psychiatric disorders. In Parkinson's disease positive results have been obtained recently by...
Quaternized phthalocyanines as a tool against melanoma and a broad spectrum of bacteria and fungi [0.03%]
季
Daniel Ziental,Eduardo Anaya-Plaza,Patrycja Talarska-Kulczyk et al.
Daniel Ziental et al.
Photodynamic therapy can be a powerful tool to combat two of the greatest challenges of 21st-century medicine - antibiotic-resistant infections and cancer. Each of these factors claims millions of human lives annually. In the presented stud...
Unveiling antioxidant and tyrosinase inhibitory activities of ESIPT-based flavonoids: DFT/TD-DFT calculations and molecular docking [0.03%]
基于ESIPT的黄酮类化合物抗氧化和酪氨酸酶抑制活性的研究:DFT/TD-DFT计算及分子对接
Xingzhu Tang,Chaofan Sun,Xin Tian et al.
Xingzhu Tang et al.
The antioxidant and tyrosinase inhibitory activities of excited-state flavonoids (fisetin and luteolin) with excited state intramolecular proton transfer process (ESIPT) property have been explored by quantum chemical methods and molecular ...
RBC membrane-coated sorafenib-MXene-Au nanocomposites for synergistic chemo-photothermal therapy of liver cancer [0.03%]
基于人红细胞膜包被的索拉非尼-MXene-金纳米复合材料肝癌协同化疗光热治疗研究
Shehab Elbeltagi,Mohammed Al-Zharani,Zienab E Eldin
Shehab Elbeltagi
Red blood cell (RBC) membrane has emerged as innovative biological nanocarriers. In this study, RBCs membrane-coated sorafenib (SF)-MXene-Au nanocomposite (SF-MX-Au@RBCs), was developed as a smart drug delivery (SDD) system, offering enhanc...
Dual-color imaging of lipid droplets and lysosomes with triphenylamine-phenyl silicon phthalocyanine nanoprobes for enhanced photodynamic therapy [0.03%]
用于增强光动力疗法的三苯胺-硅菲咯啉纳米探针实现对脂滴和溶酶体的双色成像
Xiuqin Chen,Shiqing Dong,Jianling Chen et al.
Xiuqin Chen et al.
Lipid droplets (LDs), vital in cancer cell metabolism, are prevalent in malignant tumors. Elucidating their interaction with lysosomes is essential for understanding their metabolic functions. However, simultaneous dual-color imaging and ph...
An oxygen-independent therapeutic nanosystem for fighting against hypoxic and antioxidant microenvironment of tumor [0.03%]
一种无需氧气的治疗纳米系统对抗肿瘤缺氧和抗氧化微环境
Zixuan Wang,Shuwei Nie,Manru Wang et al.
Zixuan Wang et al.
The innate hypoxic and antioxidant defendant microenvironment are the main obstacles for improving reactive oxygen species (ROS) based therapeutic efficacy against cancer. Herein, bismuth tungstate (BWO) nanoparticles (NPs) were fabricated ...
Effect of various carbon supports for TiO2 and N-doped TiO2 photocatalysts for inactivation of Escherichia coli in water under UV-visible light [0.03%]
不同碳载体对TiO2和N-TiO2光催化剂在紫外可见光下降解水中的大肠杆菌的影响研究
Mutcha Shanmukha Rao,Ashish Tiwari,Diptipriya Sethi et al.
Mutcha Shanmukha Rao et al.
This study evaluates the effectiveness of various carbon nanostructures carbon glassy spheres (CGS), carbon nanopowder (CNP), and activated carbon (AC) as supports for TiO2 and N-TiO2 photocatalysts in the inactivation of Escherichia coli (...
Pretreatment of cancer cells with inhibitors of PKCδ, EGFR, and JNK increased intracellular hypericin content and enhanced the effectiveness of photodynamic therapy [0.03%]
PKCδ、EGFR和JNK抑制剂的预处理提高了癌细胞内的羟基喜树碱含量并增强光动力学疗法的效果
Romanovová Michaela,Jendželovská Zuzana,Barčáková Ivana et al.
Romanovová Michaela et al.
Photodynamic therapy (PDT) is an effective, minimally invasive treatment for certain cancers that uses photosensitizers (PSs) to selectively destroy tumor cells upon light activation. However, the breast cancer resistance protein (BCRP) pla...
Effectiveness of blue LED in enhancing hair treatments: Analysis in different hair ethnicities [0.03%]
蓝色LED在不同种族头发护理中的增强效果分析
Juliana Ferreira-Strixino,Priscila Vareschi Cardoso Fujimoto,Priscila Maria Sarmeiro Correa Marciano Leite et al.
Juliana Ferreira-Strixino et al.
Blue LED has several clinical applications, including enhancing the permeation of cosmetics into hair and enhancing hair treatments. This study evaluated its efficacy in these processes in different hair ethnicities, in addition to analyzin...
Chemiluminescent and fluorescent properties of extracellular red pigment from Talaromyces purpureogenus [0.03%]
橘青霉外源性红色色素的化学发光和荧光性质研究
Sharad Bhatnagar,Wai Lam Tse,Haruhiko Yoneta et al.
Sharad Bhatnagar et al.
Talaromyces purpureogenus is an attractive option for natural pigment production owing to its ability to produce large amounts of water-soluble extracellular red pigments. Recently, natural pigments have been used to develop halochromic bio...