Ex vivo-stimulated cytokine expression in whole blood indicates swine influenza vaccine-induced immune memory [0.03%]
体外刺激的细胞因子表达表明了猪流感疫苗诱导的免疫记忆反应
Giulia Fantoni,Andrea Müllebner,Nimród Pálmai et al.
Giulia Fantoni et al.
Swine influenza viruses (SwIAV) pose a zoonotic threat and contribute to interspecies viral reassortment. Effective vaccination strategies are essential, yet accessible correlates of protection remain limited. We simplified a whole blood (W...
Differential macrophage immune checkpoint expression triggered by bovine-associated staphylococci [0.03%]
与牛相关葡萄球菌触发的巨噬细胞免疫检查点差异表达
Sarah Antonieta de Oliveira Veríssimo,Filipe Aguera Pinheiro,Ygor Fagundes Ruas et al.
Sarah Antonieta de Oliveira Veríssimo et al.
This study investigated whether distinct bovine-associated staphylococci can trigger expression of PD-1 and its ligand PD-L1 in RAW 264.7 murine macrophage cell line. Four well-studied strains, Staphylococcus aureus [n = 2; one from a bovin...
Development and evaluation of an ELISA based on recombinant Mb1454 antigen for the detection of specific anti-Mycobacterium bovis antibodies in cattle [0.03%]
基于Mb1454重组抗原的牛感染牛型结核分枝杆菌抗体ELISA检测方法的建立及评价
Natana M M Bueno,Carolina Reck,Lucas L Nogueira et al.
Natana M M Bueno et al.
Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is a zoonosis of global concern due to the absence of effective vaccines or treatments. The conventional diagnostic method, the single intradermal comparative cervical tuberculin tes...
Evaluation of an interferon-gamma release assay for the detection of Mycobacterium bovis using QuantiFERON-TB gold tubes in bison (Bison bison athabascae) [0.03%]
使用QuantiFERON-TB金管检测 Bison bison athabascae 中Mycobacterium bovis 的干扰素-γ释放试验的评估
Josephine Chileshe,Jeffrey M Chen,Todd Shury
Josephine Chileshe
Mycobacterium bovis (M. bovis), which causes bovine tuberculosis, is endemic in Canada's Wood Buffalo National Park and threatens the conservation of free-ranging bison. It also poses spillover risks to humans and livestock. Accurate diagno...
Rabies vaccine response in companion animals: Comparative evaluation of VSV-based pseudovirion neutralization test (PVNT) and rapid fluorescent focus inhibition test (RFFIT) [0.03%]
伴侣动物狂犬疫苗免疫效果评价：VSV基伪病毒中和试验与快速荧光灶抑制试验的比较研究
Lekshmi J Das,Santhik S Lupitha,Geetu Rose Varghese et al.
Lekshmi J Das et al.
Rabies is a fatal but vaccine-preventable zoonotic disease. Global elimination of rabies necessitates multisectoral coordination and transboundary action involving mass animal vaccinations in endemic areas. The current assays for analysing ...
Assessment of endocan as a prognostic biomarker in septic calves with diarrhoea caused by Escherichia coli K99 [0.03%]
评估内皮糖胺聚糖裂解酶产物端癌作为由大肠杆菌K99引起的腹泻性败血症小牛预后生物标志物的效果
Emre Tüfekçi,Vehbi Güneş
Emre Tüfekçi
This study aimed to determine the prognostic impact of serum Endocan levels due to E. coli K99+ driven systemic inflamatuary response syndrome (SIRS), sepsis (SE) and septic shock (SS). The samples were with 24 diarrhoeic calves and 8 healt...
Expression dynamics of antimicrobial peptides during developmental stages of Genetically Improved Farmed Tilapia (GIFT), Oreochromis niloticus [0.03%]
尼罗罗非鱼(GIFT)不同生长发育阶段的抗微生物肽表达动态研究
K L Dhanya Lenin,Anne Maria Thomas,Swapna P Antony
K L Dhanya Lenin
Fish are aquatic vertebrates that are free-living from their embryonic stages and are constantly in contact with the highly diverse and pathogen-rich external aquatic environment. The innate immune system of fish is non-specific and adapted...
Sorafenib inhibits myeloid-derived suppressor cell infiltration in canine transitional cell carcinoma [0.03%]
索拉非尼抑制犬移行细胞癌髓源性抑制细胞浸润
Shohei Yokota,Wataru Fujii,Tomoki Motegi et al.
Shohei Yokota et al.
Myeloid-derived suppressor cells (MDSCs)-immature cells with immunosuppressive properties-are promising therapeutic targets for cancer immunotherapy. However, established therapies targeting MDSCs remain lacking, and novel molecules are nee...
Matrine as a potent inhibitor of canine mammary tumors: Insights from network pharmacology, molecular docking, molecular dynamics and in vitro analysis [0.03%]
从网络药理学、分子对接、分子动力学和体外分析探讨小分子苦参碱抑制犬乳腺肿瘤的机制研究
Fida Noor,Wenwen Ding,Na Sun et al.
Fida Noor et al.
Canine mammary tumor (CMT) is the most prevailing neoplasms in female dogs. Matrine demonstrates anti-tumor effects in various organs, its mechanism in CMT treatment remains unclear. This study involved in network pharmacology, molecular do...
Analysis of IgG responses to Sarcocystis neurona in horses with equine protozoal myeloencephalitis (EPM) suggests a Th1-biased immune response [0.03%]
马伊氏脑脊髓炎（EPM） horse IgG对Sarcocystis neurona的反应分析表明免疫反应偏向于Th1型
Catherine J Angwin,Izabela de Assis Rocha,Stephen M Reed et al.
Catherine J Angwin et al.
Equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona is one of the most important neurological diseases of horses in the Americas. While seroprevalence of S. neurona in horses is high, clinical manifestation of EPM occurs ...