Chen Wu,Haiqin Chen,Yongchao Mei et al.
Chen Wu et al.
Conjugated linoleic acid (CLA) is a functional food ingredient with prebiotic properties that provides health benefits for various human pathologies and disorders. However, limited natural CLA sources in animals and plants have led microorg...
Effects of DHA on cognitive dysfunction in aging and Alzheimer's disease: The mediating roles of ApoE [0.03%]
DHA对老龄化和阿尔茨海默病认知功能障碍的影响及ApoE的介导作用
Xin Zhang,Tian Yuan,Xuhui Chen et al.
Xin Zhang et al.
The prevalence of Alzheimer's disease (AD) continues to rise due to the increasing aging population. Among the various genetic factors associated with AD, apolipoprotein E (ApoE), a lipid transporter, stands out as the primary genetic risk ...
Omega-3 long-chain polyunsaturated fatty acids: Metabolism and health implications [0.03%]
ω-3长链多不饱和脂肪酸：代谢及健康影响
Imad Khan,Mudassar Hussain,Bangzhi Jiang et al.
Imad Khan et al.
Recently, omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs) have gained substantial interest due to their specific structure and biological functions. Humans cannot naturally produce these fatty acids (FAs), making it crucial to...
How fish consumption prevents the development of Major Depressive Disorder? A comprehensive review of the interplay between n-3 PUFAs, LTP and BDNF [0.03%]
鱼类摄入如何防止重大抑郁障碍的发生？一项关于n-3 PUFAs、LTP和BDNF相互作用的全面回顾
Łukasz Kołodziej,Piotr Lech Czarny,Sylwia Ziółkowska et al.
Łukasz Kołodziej et al.
MDD (major depressive disorder) is a highly prevalent mental disorder with a complex etiology involving behavioral and neurochemical factors as well as environmental stress. The interindividual variability in response to stress stimuli may ...
The skin barrier: An extraordinary interface with an exceptional lipid organization [0.03%]
皮肤屏障：一个具有非凡脂质组织的非凡界面
Joke A Bouwstra,Andreea Nădăban,Wim Bras et al.
Joke A Bouwstra et al.
The barrier function of the skin is primarily located in the stratum corneum (SC), the outermost layer of the skin. The SC is composed of dead cells with highly organized lipid lamellae in the intercellular space. As the lipid matrix forms ...
The fats of the matter: Lipids in prebiotic chemistry and in origin of life studies [0.03%]
脂质在前生命化学和生命起源研究中的作用
Tania C B Santos,Anthony H Futerman
Tania C B Santos
The unique biophysical and biochemical properties of lipids render them crucial in most models of the origin of life (OoL). Many studies have attempted to delineate the prebiotic pathways by which lipids were formed, how micelles and vesicl...
Sabira Mohammed,Anu Bindu,Arun Viswanathan et al.
Sabira Mohammed et al.
Sphingolipids are essential components of all eukaryotic membranes. The bioactive sphingolipid molecule, Sphingosine 1-Phosphate (S1P), regulates various important biological functions. This review aims to provide a comprehensive overview o...
Triacylglycerol uptake and handling by macrophages: From fatty acids to lipoproteins [0.03%]
从脂肪酸到脂蛋白：巨噬细胞对三酰基甘油的摄取和处理
Lei Deng,Sander Kersten,Rinke Stienstra
Lei Deng
Macrophages are essential innate immune cells and form our first line of immune defense. Also known as professional phagocytes, macrophages interact and take up various particles, including lipids. Defective lipid handling can drive excessi...
FADS2 function at the major cancer hotspot 11q13 locus alters fatty acid metabolism in cancer [0.03%]
FADS2基因在主要的癌症热点11q13位点的功能可改变癌症中的脂肪酸代谢
Kumar S D Kothapalli,Hui Gyu Park,Niharika S L Kothapalli et al.
Kumar S D Kothapalli et al.
Dysregulation of fatty acid metabolism and de novo lipogenesis is a key driver of several cancer types through highly unsaturated fatty acid (HUFA) signaling precursors such as arachidonic acid. The human chromosome 11q13 locus has long bee...
Pathophysiological roles and applications of glycosphingolipids in the diagnosis and treatment of cancer diseases [0.03%]
糖鞘脂在癌症疾病诊断和治疗中的病理生理作用及应用研究进展
Xuefeng Jin,Guang-Yu Yang
Xuefeng Jin
Glycosphingolipids (GSLs) are major amphiphilic glycolipids present on the surface of living cell membranes. They have important biological functions, including maintaining plasma membrane stability, regulating signal transduction, and medi...