Takehiko Sasaki,Shunsuke Takasuga,Junko Sasaki et al.
Takehiko Sasaki et al.
Phosphoinositides are lipids that are present in the cytoplasmic leaflet of a cell's plasma and internal membranes and play pivotal roles in the regulation of a wide variety of cellular processes. Phosphoinositides are molecularly diverse d...
Toshiki Itoh,Tadaomi Takenawa
Toshiki Itoh
Among an increasing number of lipid-binding domains, a group that not only binds to membrane lipids but also changes the shape of the membrane has been found. These domains are characterized by their strong ability to transform globular lip...
Max Lafontan,Dominique Langin
Max Lafontan
Triacylglycerol (TAG) stored in adipose tissue (AT) can be rapidly mobilized by the hydrolytic action of the three main lipases of the adipocyte. The non-esterified fatty acids (NEFA) released are used by other tissues during times of energ...
Timothy Wells
Timothy Wells
With one quarter of the population of the Western world now considered obese, it is essential that we understand the factors giving rise to elevated fat deposition. This review summarizes the cellular and molecular mechanisms governing the ...
S C Cunnane,M Plourde,F Pifferi et al.
S C Cunnane et al.
Cognitive decline in the elderly, particularly Alzheimer's disease (AD), is a major socio-economic and healthcare concern. We review here the literature on one specific aspect of diet affecting AD, that of the omega3 fatty acids, particular...
Odd-numbered very-long-chain fatty acids from the microbial, animal and plant kingdoms [0.03%]
来自微生物、动物和植物界的奇数碳长链脂肪酸
Tomás Rezanka,Karel Sigler
Tomás Rezanka
Very long chain fatty acids (FAs) are important components of different classes of lipids in all organisms from bacteria to man. They include also, usually as minor components, odd-numbered FAs. These have so far been given little attention...
Soazig Le Lay,Isabelle Dugail
Soazig Le Lay
In the recent years, new advances in the biology of lipid droplets led these structures specialized for lipid storage to be considered as new universal intracellular organelles playing active roles in cell physiology. Concomitantly, studies...
Mirjam Langeveld,Johannes M F G Aerts
Mirjam Langeveld
Obesity is associated with an increased risk for insulin resistance, a state characterized by impaired responsiveness of liver, muscle and adipose tissue to insulin. One class of lipids involved in the development of insulin resistance are ...
Intestinal absorption of long-chain fatty acids: evidence and uncertainties [0.03%]
长链脂肪酸的肠道吸收：证据和不确定性
Isabelle Niot,Hélène Poirier,Thi Thu Trang Tran et al.
Isabelle Niot et al.
Over the two last decades, cloning of proteins responsible for trafficking and metabolic fate of long-chain fatty acids (LCFA) in gut has provided new insights on cellular and molecular mechanisms involved in fat absorption. To this systema...
Basal very low-density lipoprotein metabolism in response to exercise: mechanisms of hypotriacylglycerolemia [0.03%]
运动引起的极低密度脂蛋白基础代谢降低的机制研究——低三酰甘油血症的原因探究
Faidon Magkos
Faidon Magkos
Although the hypotriacylglycerolemic effect of exercise was described more than 40 years ago, the mechanisms responsible for triacylglycerol (TAG)-lowering have just recently started to be elucidated. Delayed-onset hypotriacylglycerolemia i...