Rainer H Straub
Rainer H Straub
Mental memory system has sensory memory, short-term memory, working memory, and long-term memory. Working memory "keeps things in mind in parallel" when performing complex tasks. Similar aspects can be found for immunological memory. Howeve...
Molecular mechanisms for biosynthesis and assembly of nutritionally important very long chain polyunsaturated fatty acids in microorganisms [0.03%]
微生物营养重要长链多不饱和脂肪酸生物合成及组装的分子机制
Xiao Qiu,Xi Xie,Dauenpen Meesapyodsuk
Xiao Qiu
Very long chain polyunsaturated fatty acids (VLCPUFAs) such as docosahexaenoic acid (DHA, 22:6n-3), arachidonic acid (ARA, 20:4n-6) and eicosapentaenoic acid (EPA, 20:5-n3) are nutritionally important for humans and animals. De novo biosynt...
Fat taste signal transduction and its possible negative modulator components [0.03%]
脂肪味信号转导及其可能的负调控成分
Deepankumar Shanmugamprema,Karthi Muthuswamy,Gowtham Subramanian et al.
Deepankumar Shanmugamprema et al.
The incidence of obesity and its associated diseases including diabetes and various cardiovascular disease continues to escalate. Since the energy homeostasis executes a substantial role in fat-rich food intake and body weight regulation, i...
Crystall M D Swarbrick,Jeffrey D Nanson,Edward I Patterson et al.
Crystall M D Swarbrick et al.
Thioesterases are present in all living cells and perform a wide range of important biological functions by catalysing the cleavage of thioester bonds present in a diverse array of cellular substrates. Thioesterases are organised into 25 fa...
Dong-Soon Im
Dong-Soon Im
Maresin-1, a pro-resolving lipid mediator, is drawing a great deal of attention in receptor pharmacology, largely because two distinct types of receptor molecules have been reported as the targets of maresin-1. One is retinoic acid-related ...
Squalene monooxygenase: a journey to the heart of cholesterol synthesis [0.03%]
角鲨烯单加氧酶：胆固醇合成途径的探索之旅
Ngee Kiat Chua,Hudson W Coates,Andrew J Brown
Ngee Kiat Chua
Squalene monooxygenase (SM) is a vital sterol synthesis enzyme across eukaryotic life. In yeast, it is a therapeutic target for treating certain fungal infections, and in mammals it is a rate-limiting enzyme that represents a key control po...
Peter K Lundquist,Kiran-Kumar Shivaiah,Roberto Espinoza-Corral
Peter K Lundquist
Intracellular lipid droplets are utilized for lipid storage and metabolism in organisms as evolutionarily diverse as animals, fungi, plants, bacteria, and archaea. These lipid droplets demonstrate great diversity in biological functions and...
Amira S Khan,Russell Keast,Naim A Khan
Amira S Khan
Recent advances in the field of taste physiology have clarified the role of different basic taste modalities and their implications in health and disease and proposed emphatically that there might be a distinct cue for oro-sensory detection...
Emerging roles for human glycolipid transfer protein superfamily members in the regulation of autophagy, inflammation, and cell death [0.03%]
人类糖脂转移蛋白超家族成员在自噬、炎症和细胞死亡调节中的新作用
Shrawan K Mishra,Yong-Guang Gao,Xianqiong Zou et al.
Shrawan K Mishra et al.
Glycolipid transfer proteins (GLTPs) were first identified over three decades ago as ~24kDa, soluble, amphitropic proteins that specifically accelerate the intermembrane transfer of glycolipids. Upon discovery that GLTPs use a unique, all-...
Lipid-based biomarkers for CVD, COPD, and aging - A translational perspective [0.03%]
基于脂质的生物标志物在心血管疾病、慢性阻塞性肺病和衰老研究中的转化视角
Kim Ekroos,Oksana Lavrynenko,Bjoern Titz et al.
Kim Ekroos et al.
For many diseases, there is an unmet need for new or better biomarkers for improved disease risk assessment and monitoring, as available markers lack sufficient specificity. Lipids are drawing major interest as potential candidates for fill...