New research development on trans fatty acids in food: Biological effects, analytical methods, formation mechanism, and mitigating measures [0.03%]
食品中反式脂肪酸的新研究进展：生物效应、分析方法、形成机制及缓解措施
Qin Guo,Tian Li,Yang Qu et al.
Qin Guo et al.
The trans fatty acids (TFAs) in food are mainly generated from the ruminant animals (meat and milk) and processed oil or oil products. Excessive intake of TFAs (>1% of total energy intake) caused more than 500,000 deaths from coronary heart...
A novel regulatory facet for hypertriglyceridemia: The role of microRNAs in the regulation of triglyceride-rich lipoprotein biosynthesis [0.03%]
高甘油三酯血症的一种新的调节方式：微核糖核酸在富含甘油三酯的脂蛋白生物合成中的作用研究
Masoumeh Khalifeh,Raul D Santos,Reza Kazemi Oskuee et al.
Masoumeh Khalifeh et al.
Atherosclerotic cardiovascular disease (ASCVD) is one of the major leading global causes of death. Genetic and epidemiological studies strongly support the causal association between triacylglycerol-rich lipoproteins (TAGRL) and atherogenes...
Cenk Celik,Stella Yue Ting Lee,Wei Sheng Yap et al.
Cenk Celik et al.
The endoplasmic reticulum (ER) is a complex and dynamic organelle that regulates many cellular pathways, including protein synthesis, protein quality control, and lipid synthesis. When one or multiple ER roles are dysregulated and saturated...
Comparative efficacy of omega-3 polyunsaturated fatty acids on major cardiovascular events: A network meta-analysis of randomized controlled trials [0.03%]
欧米茄-3多不饱和脂肪酸对主要心血管事件的比较疗效：随机对照试验中的网络荟萃分析
Bo Yang,Ping-Tao Tseng,Xiang Hu et al.
Bo Yang et al.
The role of omega-3 polyunsaturated fatty acids (PUFAs) in primary and secondary prevention on major cardiovascular events (MCE) is inconclusive due to the potential heterogeneity in study designs of formulas, dosages, and ratios of eicosap...
Colin A Fox,Robert O Ryan
Colin A Fox
Cardiolipin (CL) is a unique phospholipid that is fundamental to the structure and function of the highly curved cristae membranes of mitochondria. Given its distinctive cone-shaped molecular architecture, CL induces negative membrane curva...
Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities [0.03%]
花生四烯酸乙醇胺和其它N-酰基乙醇胺：具有治疗前景的脂质信号分子家族
Elliot D Mock,Berend Gagestein,Mario van der Stelt
Elliot D Mock
N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N-docosahexaenoylethanolamine (DHEA, synaptamide) and their oxygenated metabolites are a lipid me...
Yunxia Li,Xingguo Huang,Guan Yang et al.
Yunxia Li et al.
CD36, located on the cell membrane, transports fatty acids in response to dietary fat. It is a critical fatty acid sensor and regulator of lipid metabolism. The interaction between CD36 and lipid dysmetabolism and obesity has been identifie...
Parashara Shamaprasad,Chloe O Frame,Timothy C Moore et al.
Parashara Shamaprasad et al.
Skin's effectiveness as a barrier to permeation of water and other chemicals rests almost entirely in the outermost layer of the epidermis, the stratum corneum (SC), which consists of layers of corneocytes surrounded by highly organized lip...
Raman studies of the adipose tissue: Current state-of-art and future perspectives in diagnostics [0.03%]
拉曼研究在脂肪组织诊断中的现状及未来前景
Krzysztof Czamara,Zuzanna Majka,Ewa Stanek et al.
Krzysztof Czamara et al.
The last decades revealed that the adipose tissue shows an unexplored therapeutic potential. In particular, targeting the perivascular adipose tissue (PVAT), that surrounds blood vessels, can prevent cardiovascular pathologies and browning ...
Lipid-protein interactions regulating the canonical and the non-canonical NLRP3 inflammasome [0.03%]
调节经典和非经典的NLRP3炎性小体的脂质蛋白相互作用
Malvina Pizzuto,Pablo Pelegrin,Jean-Marie Ruysschaert
Malvina Pizzuto
The inflammatory response is a complex regulated effector mechanism of the innate immune system that is initiated after tissue injury or infection. The NLRP3 inflammasome is an important initiator of inflammation by regulating the activatio...