Bridging photosynthesis and photovoltaics: Biotechnological pathways for sustainable solar energy [0.03%]
连接光合作用和光电压：可持续太阳能的生物技术途径
Zhaodong Li,Zihui Gao,Haonan Song et al.
Zhaodong Li et al.
Integrating biological systems with artificial optoelectronic materials for efficient solar energy conversion has emerged as a cutting-edge and promising research direction in the pursuit of sustainable energy solutions. Natural photosynthe...
Optogenetic tools for optimizing key signalling nodes in synthetic biology [0.03%]
用于合成生物学中关键信号节点优化的光遗传学工具
Yuehui Tian,Shanshan Xu,Zidong Ye et al.
Yuehui Tian et al.
The modification of key enzymes for chemical production plays a crucial role in enhancing the yield of targeted products. However, manipulating key nodes in specific signalling pathways remains constrained by traditional gene overexpression...
Paul Ahavi,Audrey Le Gouellec,Jean-Loup Faulon
Paul Ahavi
Engineering microbial computers has been a longstanding endeavor in synthetic biology. Like other unconventional computing disciplines, the goal is to bring computation into real world scenarios. Several potential applications in bioproduct...
Ning Liu,Wenfang Liu
Ning Liu
By mimicking natural photosynthesis, the photo-enzyme coupling catalysis (PECC) for carbon dioxide conversion integrates the advantages of photocatalysis and enzymatic catalysis, offering an effective and innovative pathway for capture and ...
From dye exclusion to high-throughput screening: A review of cell viability assays and their applications [0.03%]
从拒染到高通量筛选：细胞活力测定法及其应用综述
Kumar Vishven Naveen,Akanksha Tyagi,Omnia Mohammed Hamid Ibrahim et al.
Kumar Vishven Naveen et al.
Cell viability assays (CVAs) are widely used in cell biology, biomedical research, drug development, and biotechnology to assess cell health, proliferation, cytotoxicity, and functional activity under various conditions. Key applications sp...
Advances in transcription factor-based biosensors for natural product biosynthesis: Optimization, emerging technologies, and future prospects [0.03%]
基于转录因子的次级代谢生物传感器研究进展：优化、新兴技术及未来前景
Xiaohan Zhang,Xinping Wu,Hui Chen et al.
Xiaohan Zhang et al.
Natural products (NPs) are increasingly applied in food, medicine, and biotechnology. However, their biosynthesis remains constrained by low titers and yields. Transcription factor-based biosensors (TFBs) can convert biological signals into...
Biosynthesis of high-value chorismate derivatives in Escherichia coli: Recent advances and perspectives [0.03%]
大肠杆菌中高附加值香豆酸衍生物生物合成的研究进展与展望
Xuewei Pan,Shuran Jiang,Mi Tang et al.
Xuewei Pan et al.
Chorismate serves not only as a critical branch point for aromatic amino acids biosynthesis, but also as an essential precursor for various high-value aromatic compounds. Currently, the sustainable production of chorismate derivatives is at...
Strategies to Enhance Stability of Cryopreservation Processes for Cell-Based Products [0.03%]
提高细胞基产品冷冻保存过程稳定性的策略
Yuki Uno,Yusuke Hayashi,Hirokazu Sugiyama et al.
Yuki Uno et al.
The projected expansion of the global market for cell manufacturing, which contributes to regenerative medicine and cell therapies, warrants the designing and development of scalable cryopreservation processes for cell-based products (CBPs)...
Capitalizing on mechanistic insights to power design of future-ready intracellular optogenetics tools [0.03%]
基于机理的新一代细胞内光遗传工具的设计与开发
Si Bin Chew,Emily Harjabrata,Cameron Jing Han Goh et al.
Si Bin Chew et al.
Intracellular optogenetics represents a rapidly advancing biotechnology that enables precise, reversible control of protein activity, signaling dynamics, and cellular behaviours using genetically encoded, light-responsive systems. Originall...
Machine learning methods for small data and upstream bioprocessing applications: A comprehensive review [0.03%]
小数据和上游生物工艺应用的机器学习方法综述
Johnny Peng,Thanh Tung Khuat,Katarzyna Musial et al.
Johnny Peng et al.
Data are crucial for machine learning (ML) applications, yet acquiring large datasets can be costly and timeconsuming, especially in complex, resource-intensive fields like biopharmaceuticals. A key process in this industry is upstream biop...