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Metabolic engineering strategies for enhanced microbial synthesis of lacto-N-neotetraose: a key acetylated human milk oligosaccharide

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Human milk oligosaccharides (HMOs) are complex carbohydrates crucial for infant nutrition, with lacto-N-neotetraose (LNnT) being a key acetylated component that makes up about 10 % of total HMOs. The synthesis of LNnT involves a sequential enzymatic process th... ...