Dipanka Tanu Sarmah,Rubi Parveen,Jayendrajyoti Kundu et al.
Dipanka Tanu Sarmah et al.
Tuberculosis (TB) is a pervasive and devastating air-borne disease caused by the organisms belonging to the Mycobacterium tuberculosis (Mtb) complex. Currently, it is the global leader in infectious disease-related death in adults. The proc...
Recent advancements to engineer mesenchymal stem cells and their extracellular vesicles for targeting and destroying tumors [0.03%]
工程化间充质干细胞及其外泌体用于靶向和消灭肿瘤的最新进展
Mohsen Karami Fath,Zahra Moayedi Banan,Reza Barati et al.
Mohsen Karami Fath et al.
Mesenchymal stem cells (MSCs) have the ability to migrate into tumor sites and release growth factors to modulate the tumor microenvironment. MSC therapy have shown a dual role in cancers, promoting or inhibiting. However, MSCs could be use...
Mathematical and physical considerations indicating that the cell genome is a read-write memory [0.03%]
数学和物理方面的考虑表明细胞基因组是一种可读写的记忆体
Antonis Mistriotis
Antonis Mistriotis
The molecular mechanisms that govern biological evolution have not been fully elucidated so far. Recent studies indicate that regulatory proteins, acting as decision-making complex devices, can accelerate or retard the evolution of cells. S...
Corrado Spadafora
Corrado Spadafora
An increasing body of data are revealing key roles of epigenetics in evolutionary processes. The scope of this manuscript is to assemble in a coherent frame experimental evidence supporting a role of epigenetic factors and networks, active ...
Development as explanation: Understanding phenotypic stability and variability after the failure of genetic determinism [0.03%]
发展作为解释：理解遗传决定论失败后的表型稳定性和变异性
David S Moore,Robert Lickliter
David S Moore
In the predominately gene-centered view of 20th century biology, the relationship between genotype and phenotype was essentially a relationship between cause and effect, between a plan and a product. Abandoning the idea of genes as inherite...
S P R Rose
S P R Rose
I argue that Baverstock's demotion of the gene in favour of the cellular phenotype is still too limited, and that phenotypes must be considered at multiple irreducible levels. I emphasise process thinking and the significance of agency in l...
Yaron Ilan
Yaron Ilan
Disorder and noise are inherent in biological systems. They are required to provide systems with the advantages required for proper functioning. Noise is a part of the flexibility and plasticity of biological systems. It provides systems wi...
J S Torday
J S Torday
The case has previously been made for the 'Singularity of Nature" based on homologies between the inorganic and the organic. But a causal explanation for those homologies was not provided. The following is a hypothetical way to understand h...
Static magnetic field: A potential tool of controlling stem cells fates for stem cell therapy in osteoporosis [0.03%]
静态磁场：控制干细胞命运以治疗骨质疏松症的潜在工具
Jianping Wang,Peng Shang
Jianping Wang
Osteoporosis is a kind of bone diseases characterized by dynamic imbalance of bone formation and bone absorption, which is prone to fracture, and seriously endangers human health. At present, there is a lack of highly effective drugs for it...
Long non-coding RNAs (lncRNAs) in hepatocellular carcinoma progression: Biological functions and new therapeutic targets [0.03%]
肝细胞癌进展中的长链非编码RNA（lncRNA）：生物功能和新的治疗靶点
Mehrdad Hashemi,Sepideh Mirzaei,Mohammad Arad Zandieh et al.
Mehrdad Hashemi et al.
Liver is an important organ in body that performs vital functions such as detoxification. Liver is susceptible to development of cancers, and hepatocellular carcinoma (HCC) is among them. 75-85% of liver cancer cases are related to HCC. The...