Cold snapshots of DNA repair: Cryo-EM structures of DNA-PKcs and NHEJ machinery [0.03%]
冷的DNA修复快照：DNA-PKcs和NHEJ机器人的Cryo-EM结构
Himani Amin,Sayma Zahid,Chloe Hall et al.
Himani Amin et al.
The proteins and protein assemblies involved in DNA repair have been the focus of a multitude of structural studies for the past few decades. Historically, the structures of these protein complexes have been resolved by X-ray crystallograph...
How can Phycobilisome, the unique light harvesting system in certain algae working highly efficiently: The connection in between structures and functions [0.03%]
藻胆体的结构与功能之间的关系及其高效光捕获机制
Runze Liu,Zhang-He Zhen,Wenjun Li et al.
Runze Liu et al.
Algae, which are ubiquitous in ecosystems, have evolved a variety of light-harvesting complexes to better adapt to diverse habitats. Phycobilisomes/phycobiliproteins, unique to cyanobacteria, red algae, and certain cryptomonads, compensate ...
Cells and sounds [0.03%]
细胞与声音
Michael Spitzer
Michael Spitzer
Shannon's (informational) dissipation as the major engine leading to living dynamic and the origin of self [0.03%]
香农(信息)耗散是生命动态的主要引擎及自我的起源
Salvatore Chirumbolo,Antonio Vella
Salvatore Chirumbolo
Growth or death? Control of cell destiny by mTOR and autophagy pathways [0.03%]
生长还是死亡？mTOR和自噬途径控制细胞命运
Mahmoud I Khalil,Mohamad M Ali,Jasmine Holail et al.
Mahmoud I Khalil et al.
One of the central regulators of cell growth, proliferation, and metabolism is the mammalian target of rapamycin, mTOR, which exists in two structurally and functionally different complexes: mTORC1 and mTORC2; unlike m TORC2, mTORC1 is acti...
How an emergent cosmology of a nonlocally unified, meaningfully in-formed and holographically manifested Universe can underpin and frame the biological embodiment of quantum entanglement [0.03%]
一个非局域统一的、有意义地信息构成和全息展现的宇宙的涌现宇宙学如何能成为量子纠缠的生物学体现的基石和框架
Jude Currivan
Jude Currivan
With a Nobel Prize for Physics widely viewed as only given for 'settled' science, the award then essentially accepts the validity of universal nonlocality. Other key discoveries and insights in recent years are also progressively pointing t...
Computational approaches for modeling and structural design of biological systems: A comprehensive review [0.03%]
用于生物系统建模和结构设计的计算方法：全面综述
Ekambaram Gayathiri,Palanisamy Prakash,Priya Kumaravel et al.
Ekambaram Gayathiri et al.
The convergence of biology and computational science has ushered in a revolutionary era, revolutionizing our understanding of biological systems and providing novel solutions to global problems. The field of genetic engineering has facilita...
Xiao-Xia Chai,Jie Liu,Tong-Yao Yu et al.
Xiao-Xia Chai et al.
The mechanical environment is important for tumorigenesis and progression. Tumor cells can sense mechanical signals by mechanosensitive receptors, and these mechanical signals can be converted to biochemical signals to regulate cell behavio...
HIF-1α and periodontitis: Novel insights linking host-environment interplay to periodontal phenotypes [0.03%]
缺氧诱导因子-1α与牙周炎：连接宿主环境交互作用与牙周表型的新观点
Chao Shan,YuNing Xia,Zeyu Wu et al.
Chao Shan et al.
Periodontitis, the sixth most prevalent epidemic disease globally, profoundly impacts oral aesthetics and masticatory functionality. Hypoxia-inducible factor-1α (HIF-1α), an oxygen-dependent transcriptional activator, has emerged as a piv...
Xin Liu,Weipin Niu,Shuqing Zhao et al.
Xin Liu et al.
Fibrosis is a pathological process that occurs in various organs, characterized by excessive deposition of extracellular matrix (ECM), leading to structural damage and, in severe cases, organ failure. Within the fibrotic microenvironment, m...