Yeak-Wun Quek,Yu-Ting Kang,Hsu Chih Huang et al.
Yeak-Wun Quek et al.
Fine particulate matter (PM2.5) is a common major air pollutant associated with decreased lung function, induced allergic airway inflammation closely correlated with chronic lung diseases. Angiopoietin-like protein 4 (ANGPTL4) is a cytokine...
Knockdown of SDCBP induces autophagy to promote cardiomyocyte growth and angiogenesis in hypoxia/reoxygenation model [0.03%]
SDCBP基因敲低通过诱导自噬促进缺氧/复氧模型中心肌细胞增殖及新生血管形成
Ling Gao,Wanqian Liu
Ling Gao
Objective: Angina, myocardial infarction, and even mortality can result from myocardial ischemia (MI). Angiogenesis facilitates tissue repair, lessens cell damage, and ensures that ischemic tissues receive blood and oxyge...
Agrimonolide inhibits glycolysis in ovarian cancer cells by regulating HIF1A [0.03%]
Agrimonolide通过调节HIF1A抑制卵巢癌细胞的糖酵解作用
Yi Yang,Huimin Wang,Qiong Wei et al.
Yi Yang et al.
Background: Ovarian cancer is one of the most common tumors affecting females, significantly disrupting their quality of life. Agrimonolide, an extract derived from Agrimony (Agrimonia pilosa Ledeb.), has been shown to ex...
Molecular dynamics of DNA repair and carcinogen interaction: Implications for cancer initiation, progression, and therapeutic strategies [0.03%]
DNA修复和致癌物相互作用的分子动力学：对癌症发生、发展及治疗策略的意义
Eman Alyafeai,Eskandar Qaed,Haitham Saad Al-Mashriqi et al.
Eman Alyafeai et al.
The integrity of the genetic material in human cells is continuously challenged by environmental agents and endogenous stresses. Among these, environmental carcinogens are pivotal in initiating complex DNA lesions that can lead to malignant...
HOXA1 promotes epithelial-mesenchymal transition and malignant characteristics of laryngeal squamous cell carcinoma [0.03%]
HOXA1促进喉鳞状细胞癌上皮间质转化及恶性行为
Jun Wu,Xiaofeng Gu
Jun Wu
Despite considerable advancements in the diagnosis and treatment of LSCC, there has been no significant improvement in survival rate. Consequently, identifying molecular targets for this cancer is of paramount importance. HOXA1, a constitue...
Understanding the nucleotide composition and patterns of codon usage in the expression of human oral cancer genes [0.03%]
人类口腔癌基因表达中的核苷酸组成及密码子使用模式的理解
Tarikul Huda Mazumder,Arif Uddin
Tarikul Huda Mazumder
Oral squamous cell carcinoma (OSCC) is primarily known as oral cancer (OC) that mostly occurs in mouth, lips and tongue. Mutations in some of the genes cause OC and some genes are risk factors for progression of OC. In this study, we analyz...
Apiole, an important constituent of parsley, is a mixed-type inhibitor of the CYP1A subfamily [0.03%]
芹菜子醇是一种重要的伞形科植物茋类成分，是CYP1A亚家族的混合型抑制剂
J J Espinosa-Aguirre,R Camacho-Carranza,S L Hernández-Ojeda et al.
J J Espinosa-Aguirre et al.
Apiole (1-allyl-2,5-dimethoxy-3,4-methylenedioxybenzene) and parsley leaves ethanolic extract containing it inhibit the rat liver microsomal ethoxy- and methoxyresorufin-O-deacetylase activities associated with cytochrome P450 (CYP) 1A1 and...
CircRNA ATF6 suppresses bladder cancer cell proliferation and migration via miR-146a-5p/FLNA axis [0.03%]
环状RNA ATF6通过miR-146a-5p/FLNA轴抑制膀胱癌细胞增殖和迁移
Bing Lu,Yongqiang Zhou,Zheng Ma et al.
Bing Lu et al.
Background: Bladder cancer (BCa) is the most common malignancy with increasing morbidity and mortality. Circular RNA (circRNA) ATF6 level was downregulated in BCa after GSE92675 CircRNA microarray dataset was analyzed usi...
NTSR1 promotes epithelial-mesenchymal transition and metastasis in lung adenocarcinoma through the Wnt/β-catenin pathway [0.03%]
NTSR1通过Wnt/β-catenin信号通路促进肺腺癌的上皮间质转化和转移
Zhihao Zhang,Dongliang Zhang,Kai Su et al.
Zhihao Zhang et al.
Background: Lung adenocarcinoma (LUAD) patients are implicated in poor prognoses and increased mortality rates. Metastasis, as a leading cause of LUAD-related deaths, requires further investigation. Highly metastatic canc...
Therapeutic potential of curcumin in autophagy modulation: Insights into the role of transcription factor EB [0.03%]
姜黄素在自噬调节中的治疗潜力：转录因子EB的作用机制初探
Shabnam Radbakhsh,Prashant Kesharwani,Amirhossein Sahebkar
Shabnam Radbakhsh
Transcription factor EB (TFEB) is a basic Helix-Loop-Helix/Leucine Zipper (bHLHZip) class of DNA-binding proteins, which can control the expression of genes included in the autophagy-lysosomal pathway. TFEB regulates the autophagic flux by ...