Construction of multi-layered Zn-modified TiO2 coating by ultrasound-auxiliary micro-arc oxidation: Microstructure and biological property [0.03%]
超声波辅助微弧氧化法制备多层Zn改性TiO2涂层：微观结构及生物性能
You Lv,Siqin Sun,Xinxin Zhang et al.
You Lv et al.
Surfaces with desirable cytocompatibility and bactericidal ability are favoured for orthopaedic implants to stimulate osteogenic activity and to prevent implant-associated infection. In this work, we creatively introduce ultrasonic vibratio...
The influence of zirconium content on the microstructure, mechanical properties, and biocompatibility of in-situ alloying Ti-Nb-Ta based β alloys processed by selective laser melting [0.03%]
锆含量对选择性激光熔化近实时合金Ti-Nb-Ta基β合金的微观结构、力学性能和生物相容性的影响
Weihuan Kong,Sophie C Cox,Yu Lu et al.
Weihuan Kong et al.
This study investigates Ti-Nb-Ta based β alloys with different zirconium additions (0, 5, 9 wt%) manufactured by SLM. A low level of as-fabricated defects is obtained: the relative density of TNT (Z) alloys is >99.97% with the keyhole size...
Mg-Fe layered double hydroxides modified titanium enhanced the adhesion of human gingival fibroblasts through regulation of local pH level [0.03%]
通过调节局部pH值,Mg-Fe层状双氢氧化物修饰的钛提高了人牙龈成纤维细胞的粘附力
Yijia Yin,Linjia Jian,Baoe Li et al.
Yijia Yin et al.
The durability of dental implants is closely related to osseointegration and surrounding soft tissue sealing. Appropriate local pH favors fibroblasts adhesion and contributes to soft tissue sealing. Layered double hydroxides (LDHs) are char...
ZnO-loaded DNA nanogels as neutrophil extracellular trap-like structures in the treatment of mouse peritonitis [0.03%]
载有DNA纳米凝胶的ZnO作为中性粒细胞外捕网样结构用于治疗小鼠腹膜炎
Yu-Fon Chen,Yee-Hsuan Chiou,Yi-Cheng Chen et al.
Yu-Fon Chen et al.
Neutrophil extracellular traps (NETs) are chromatin-based structures that are released from neutrophils during infections and prevent microbes from spreading in the body through efficient degradation of their composition. Based on this chro...
Development of "on-demand" thermo-responsive hydrogels for anti-cancer drugs sustained release: Rational design, in silico prediction and in vitro validation in colon cancer models [0.03%]
"按需"热响应水凝胶的发展用于抗癌药物的持续释放：合理设计，计算机模拟预测和体外结肠癌模型验证
Gustavo Carreño,Alfredo Pereira,Fabián Ávila-Salas et al.
Gustavo Carreño et al.
A rational design accurate based on the use of Statistical Design of the Experiments (DoE) and Molecular Dynamics Simulations Studies allows the prediction and the understanding of thermo-responsive hydrogels prepared regarding their gelati...
A polydopamine-assisted strontium-substituted apatite coating for titanium promotes osteogenesis and angiogenesis via FAK/MAPK and PI3K/AKT signaling pathways [0.03%]
聚多巴胺辅助的钛表面锶掺杂磷灰石涂层通过FAK/MAPK和PI3K/AKT信号转导通路促进成骨与成血管进程
Yiting Sun,Yaxin Li,Yu Zhang et al.
Yiting Sun et al.
Early osteointegration is essential for biomedical implants. Surface modifications can significantly compensate for an implant's lack of biocompatibility and osteo-differentiation. They can also be designed to promote angiogenesis in order ...
Combination of multifunctional ursolic acid with kinase inhibitors for anti-cancer drug carrier vesicles [0.03%]
乌索酸与激酶抑制剂结合用于抗癌药物载体 Vesicles 的研究
A Lőrincz,J Mihály,A Wacha et al.
A Lőrincz et al.
A sterically stabilized unilamellar nanocarrier vesicle (SSV) system containing dipalmitoylphosphatidylcholine, cholesterol, ursolic acid and PEGylated phospholipid has been developed by exploiting the structural advantages of ursolic acid:...
Physical and chemical properties of carbon nanotubes in view of mechanistic neuroscience investigations. Some outlook from condensed matter, materials science and physical chemistry [0.03%]
从机制神经科学调查的角度看碳纳米管的物理化学性质。来自凝聚态，材料科学和物理化学的一些展望
Stefano A Mezzasalma,Lucia Grassi,Mario Grassi
Stefano A Mezzasalma
The open border between non-living and living matter, suggested by increasingly emerging fields of nanoscience interfaced to biological systems, requires a detailed knowledge of nanomaterials properties. An account of the wide spectrum of p...
Dual-functional antibacterial and osteogenic nisin-based layer-by-layer coatings [0.03%]
具有双重功能的抗菌和成骨乳链菌素层层 coating
Charlotte Roupie,Béatrice Labat,Sandrine Morin-Grognet et al.
Charlotte Roupie et al.
Implanted biomaterials can be regarded in a cornerstone in the domain of bone surgery. Their surfaces are expected to fulfil two particular requirements: preventing the settlement and the development of bacteria, and stimulating bone cells ...
Double-responsive hyaluronic acid-based prodrugs for efficient tumour targeting [0.03%]
双响应型透明质酸前药用于高效肿瘤靶向治疗
Vincenzo Quagliariello,Arianna Gennari,Som Akshay Jain et al.
Vincenzo Quagliariello et al.
Hyaluronic acid (HA)-based prodrugs bearing double-responsive (acid pH or oxidation) boronates of catechol-containing drugs were used to treat xenografted human prostate tumours (LNCaP) in SCID mice. The HA prodrugs accumulated significantl...