Development of a device useful to reproducibly produce large quantities of viable and uniform stem cell spheroids with controlled diameters [0.03%]
一种可生产大量均匀且可控直径的干细胞球体设备的研发
Monize Caiado Decarli,Mateus Vidigal de Castro,Júlia Adami Nogueira et al.
Monize Caiado Decarli et al.
Three-dimensional cellular aggregates can mimic the natural microenvironment of tissues and organs and obtaining them through controlled and reproducible processes is mandatory for scaling up and implementing drug cytotoxicity and efficacy ...
Osteogenic and anti-inflammatory potential of oligochitosan nanoparticles in treating osteomyelitis [0.03%]
寡壳聚糖纳米颗粒在治疗骨髓炎中的成骨和抗炎潜力
Shixiong Zhang,Guo Chen,Mohong Wang et al.
Shixiong Zhang et al.
Osteomyelitis is commonly developed via hematogenous spreading or direct inoculation of bacteria from orthopedics trauma. Pathogens-induced bone destruction impedes the penetration of antibiotics to the infection site, and the severe inflam...
Enhancing the bioactivity of melt electrowritten PLLA scaffold by convenient, green, and effective hydrophilic surface modification [0.03%]
通过简便、绿色和有效的亲水性表面改性提高熔融电写制PLLA支架的生物活性
Jie Meng,Francesco Boschetto,Shinichi Yagi et al.
Jie Meng et al.
As an emerging additive manufacturing (AM) technique, melt electrospinning writing (MEW) is used to fabricate three-dimensional (3D) submicron filament-based scaffolds with adjustable pore size and customized structure for bone regeneration...
Optimal structural and physical properties of aerogels for promoting robust neurite extension in vitro [0.03%]
用于体外促进稳健轴突延伸的气凝胶材料的最佳结构和物理性能
Martina Rodriguez Sala,Omar Skalli,Firouzeh Sabri
Martina Rodriguez Sala
Cell behaviour is influenced by external factors including the physical properties of the substrate such as its surface topography and stiffness. Recent studies have demonstrated the potential of aerogels as biomaterials and specifically as...
Effect of recombinant BMP-2 and erythropoietin on osteogenic properties of biomimetic PLA/PCL/HA and PHB/HA scaffolds in critical-size cranial defects model [0.03%]
rhBMP-2和EPO联合促进仿生PLA/PCL/HA及PHB/HA支架材料修复大鼠颅骨缺损的能力及其成骨作用研究
Fedor Senatov,Anna Zimina,Alexander Chubrik et al.
Fedor Senatov et al.
Osteoplastic materials PLA/PCL/HA and PHB/HA and scaffolds with a highly porous structure based on them with potential applications in regenerative medicine have been obtained by solvent casting with thermopressing and salt leaching for PLA...
A loofah-inspired scaffold with enhanced mimicking mechanics and tumor cells distribution for in vitro tumor cell culture platform [0.03%]
一种具有增强模拟力学和肿瘤细胞分布的仿丝瓜络支架的体外肿瘤细胞培养平台
Xingxing Liu,Sijia Fu,Yongjie Jiao et al.
Xingxing Liu et al.
Tumor cells cultured in a physiologically related three-dimensional (3D) matrix can replicate many basic characteristics of tumor tissue. Tumor tissues are harder than normal, so when using hydrogels for 3D tumor cell culture, attempts have...
Silk-inspired fiber implant with multi-cues enhanced bionic microenvironment for promoting peripheral nerve repair [0.03%]
一种丝蛋白仿生微环境导管促进周围神经再生修复
Xiaoli Chen,Xiaoxuan Tang,Yaling Wang et al.
Xiaoli Chen et al.
Successful repair and desirable functional recovery of large-gap nerve injuries using artificial nerve implants remains a significant clinical challenge. The beneficial bionic microenvironment within scaffolds can significantly promote the ...
Influence of hydrophilic polymers on mechanical property and wound recovery of hybrid bilayer wound dressing system for delivering thermally unstable probiotic [0.03%]
亲水性聚合物对递送热不稳定的益生菌的双层伤口敷料系统的机械性能和伤口恢复的影响研究
Jung Suk Kim,Heesun Yu,Mi Ran Woo et al.
Jung Suk Kim et al.
In this study, a novel hybrid bilayer wound dressing (HBD) has been developed for delivering a thermally unstable probiotic, Lactobacillus brevis. The HBD was composed of two layer, a hydrocolloid layer and a Lactobacillus brevis-loaded hyd...
Micro-textured silicone-based implant fabrication using electrospun fibers as a sacrificial template to suppress fibrous capsule formation [0.03%]
使用静电纺丝纤维作为牺牲模板制造微纹理硅胶植入物以抑制纤维囊形成
Juhwan Choi,Byung Ho Shin,Taehyeon Kim et al.
Juhwan Choi et al.
Conventionally, macro-textured surfaces comprising several hundred micrometer-sized patterns are used to minimize silicone-based breast implant complications, including capsular contracture. However, because of the recent cases of breast im...
Polysucrose hydrogel and nanofiber scaffolds for skin tissue regeneration: Architecture and cell response [0.03%]
用于皮肤组织再生的聚蔗糖水凝胶和纳米纤维支架：结构与细胞响应
Itisha Chummun,Fanny Gimié,Nowsheen Goonoo et al.
Itisha Chummun et al.
Scaffolds capable of mediating overlapping multi-cellular activities to support the different phases of wound healing while preventing scarring are essential for tissue regeneration. The potential of polysucrose as hydrogels and electrospun...