Microfluidic-templating alginate microgels crosslinked by different metal ions as engineered microenvironment to regulate stem cell behavior for osteogenesis [0.03%]
通过不同金属离子交联的海藻酸微凝胶作为工程微环境来调控干细胞行为以促进成骨作用的微流控模板技术研究
Yujie Zhang,Chuanfeng An,Yang Zhang et al.
Yujie Zhang et al.
Cell microenvironment is a collection of dynamic biochemical and biophysical cues which functions as the key factor in determining cell behavior. Encapsulating single cell into micrometer-scale hydrogels which mimics the cell microenvironme...
Physicochemical and biological properties of carboxymethyl chitosan zinc (CMCS-Zn)/α‑calcium sulfate hemihydrate (α-CSH) composites [0.03%]
羧甲基壳聚糖锌（CMCS-Zn）/α-半水硫酸钙（α-CSH）复合材料的理化和生物性能研究
Jianchun Lin,Daorong Xu,Zhongguo Liu et al.
Jianchun Lin et al.
To improve the osteoinductivity, antibacterial activity, and clinical application of calcium sulfate hemihydrate (CSH), carboxymethyl chitosan zinc (CMCS-Zn) and α-CSH were prepared using different mass ratios. The setting time and injecta...
Peptide-modified substrate enhances cell migration and migrasome formation [0.03%]
肽修饰的基质促进细胞迁移和迁移小体的形成
Shogo Saito,Masayoshi Tanaka,Soichiro Tatematsu et al.
Shogo Saito et al.
Extracellular vesicles (EVs) are cell-to-cell communication tools. Migrasomes are recently discovered microscale EVs formed at the rear ends of migrating cells, and thus are suggested to be involved in communicating with neighboring cells. ...
Cellular defense system-destroying nanoparticles as a platform for enhanced chemotherapy against drug-resistant cancer [0.03%]
破坏细胞防御系统的纳米颗粒作为对抗药物抵抗性癌症的增强化学疗法平台
Boyi Niu,Kaixin Liao,Yixian Zhou et al.
Boyi Niu et al.
Cellular defense system represented by glutathione (GSH) greatly weakens the outcomes of cancer therapy by antioxidation and detoxification. GSH depletion has been proved to be an effective way to enhance the efficacy of reactive oxygen spe...
Multifunctional 3D printed porous GelMA/xanthan gum based dressing with biofilm control and wound healing activity [0.03%]
具有生物膜控制和伤口愈合活性的多功能3D打印Por GelMA/黄原胶基敷料
Zhenming Yang,Xuehong Ren,Yu Liu
Zhenming Yang
Bacterial infections are the major challenges of wound treatment in current clinical applications. In this study, Three-dimensional (3D) antibacterial wound dressing has been fabricated via introducing N-halamine/TiO2 to gelatin methacrylat...
Bioinspired macrophage-targeted anti-inflammatory nanomedicine: A therapeutic option for the treatment of myocarditis [0.03%]
仿生巨噬体定向抗炎纳米医药：治疗心肌炎的疗法选择
Riki Toita,Takahito Kawano,Masaharu Murata et al.
Riki Toita et al.
Myocarditis is a disease characterized by inflammation of the heart muscle, which increases the risk of dilated cardiomyopathy and heart failure. Macrophage migration is a major histopathological hallmark of myocarditis, making macrophages ...
Micro-arc oxidation-assisted sol-gel preparation of calcium metaphosphate coatings on magnesium alloys for bone repair [0.03%]
微弧氧化辅助溶胶-凝胶法在镁合金上制备钙焦磷酸盐涂层用于骨修复
Yanping Liu,Xian Cheng,Xiyuan Wang et al.
Yanping Liu et al.
Calcium phosphate coating is an attractive surface modification strategy for magnesium alloys, since it can increase their corrosion resistance and endow them with osteogenic function simultaneously. Herein, a calcium metaphosphate (CMP) co...
Enhanced osteogenesis and angiogenesis of calcium phosphate cement incorporated with zinc silicate by synergy effect of zinc and silicon ions [0.03%]
锌硅酸盐改性的磷酸钙骨水泥的促血管生成和成骨作用的研究中的锌离子和硅离子的协同效应
Teliang Lu,Jing Zhang,Xinyuan Yuan et al.
Teliang Lu et al.
Calcium phosphate cement (CPC) with good injectability and osteoconductivity plays important roles in bone grafting application. Much attention has been paid to achieve multifunctionality through incorporating trace elements into CPC. Silic...
Injectable nanocomposite hydrogels as an emerging platform for biomedical applications: A review [0.03%]
用于生物医学应用的新兴平台：可注射的纳米复合水凝胶综述
Amir Mellati,Elham Hasanzadeh,Mazaher Gholipourmalekabadi et al.
Amir Mellati et al.
Hydrogels have attracted much attention for biomedical and pharmaceutical applications due to the similarity of their biomimetic structure to the extracellular matrix of natural living tissues, tunable soft porous microarchitecture, superb ...
Cold-atmospheric plasma augments functionalities of hybrid polymeric carriers regenerating chronic wounds: In vivo experiments [0.03%]
冷大气等离子体增强混合聚合载体再生慢性伤口的功能：活体实验
Yun-Hsuan Chen,Er-Yuan Chuang,Pei-Ru Jheng et al.
Yun-Hsuan Chen et al.
The skin possesses an epithelial barrier. Delivering growth factors to deeper wounds is usually rather challenging, and these typically restrict the therapeutic efficacy for chronic wound healing. Efficient healing of chronic wounds also re...