Photosensitizer-based metal-organic frameworks for highly effective photodynamic therapy [0.03%]
基于光敏剂的金属有机框架用于高效率光动力治疗
Samara Rodrigues Alves,Italo Rodrigo Calori,Antonio Claudio Tedesco
Samara Rodrigues Alves
Photodynamic therapy (PDT) uses a photosensitizer, molecular oxygen, and visible light as an alternative clinical protocol against located malignant tumors and other diseases. More recently, PDT has been combined to immunotherapy as a promi...
Resveratrol-loaded titania nanotube coatings promote osteogenesis and inhibit inflammation through reducing the reactive oxygen species production via regulation of NF-κB signaling pathway [0.03%]
负载白藜芦醇的二氧化钛纳米管涂层通过调控NF-κB信号通路减少活性氧产生，从而促进成骨和抑制炎症反应
Rui Yang,Yurong Yan,Zheng Wu et al.
Rui Yang et al.
Although titanium and its alloys are widely used in bone surgeries, the implantation failures caused by sterile inflammation still occur. The excessive reactive oxygen species (ROS) in the peri-implant region are considered to cause inflamm...
NIR and glutathione trigger the surface release of methotrexate linked by Diels-Alder adducts to anisotropic gold nanoparticles [0.03%]
近红外和谷胱甘肽触发各向异性金纳米颗粒表面Diels-Alder连接的甲氨蝶呤释放
Karen Bolaños,Macarena Sánchez-Navarro,Ernest Giralt et al.
Karen Bolaños et al.
The administration and controlled release of drugs over time remains one of the greatest challenges of science today. In the nanomaterials field, anisotropic gold nanoparticles (AuNPs) with plasmon bands centered at the near-infrared region...
Thermosensitive hydrogel-functionalized gold nanorod/mesoporous MnO2 nanoparticles for tumor cell-triggered drug delivery [0.03%]
用于肿瘤细胞触发药物传递的热敏水凝胶功能化的金纳米棒/介孔MnO2纳米颗粒
Zheng Zhang,Yuanhui Ji,Chengqi Lin et al.
Zheng Zhang et al.
MnO2 owns distinct redox, imaging, and degradable properties corresponding to the tumor microenvironment. However, the onefold structure and non-modifiable property cause many obstacles to anticancer applications. In this report, we first p...
Superior low-immunogenicity of tilapia type I collagen based on unique secondary structure with single calcium binding motif over terrestrial mammals by inhibiting activation of DC intracellular Ca2+-mediated STIM1-Orai1/NF-кB pathway [0.03%]
基于独特二级结构的单钙结合基序的罗非鱼I型胶原在抑制DC细胞内Ca2+-介导的STIM1-Orai1/NF-кB通路激活方面优于陆地哺乳动物，表现出优越的低免疫原性
Xiao Xu,Baiyan Sui,Xin Liu et al.
Xiao Xu et al.
The reason for low- or non-immunogenicity of fish collagens is still in doubt, which, to some extent, bottlenecks their production and clinical application as biomaterials. Employing bovine or porcine type I collagens (BCI or PCI) as contro...
Development of 3D culture scaffolds for directional neuronal growth using 2-photon lithography [0.03%]
利用双光子光刻技术开发用于定向神经生长的3D培养支架的发展
Lokesh Agrawal,Menouer Saidani,Laurent Guillaud et al.
Lokesh Agrawal et al.
Conventional applications of transplant technology, applied to severe traumatic injuries of the nervous system, have met limited success in the clinics due to the complexity of restoring function to the damaged tissue. Neural tissue enginee...
A bimetallic load-bearing bioceramics of TiO2 @ ZrO2 integrated polycaprolactone fibrous tissue construct exhibits anti bactericidal effect and induces osteogenesis in MC3T3-E1 cells [0.03%]
TiO2 @ ZrO2集成聚ε-己内酯纤维组织构建的双金属承重生物陶瓷具有抗菌性，并能在MC3T3-E1细胞中诱导成骨作用
Rupesh Kandel,Se Rim Jang,Sita Shrestha et al.
Rupesh Kandel et al.
Bioactive mesoporous binary metal oxide nanoparticles allied with polymeric scaffolds can mimic natural extracellular matrix because of their self-mineralized functional matrix. Herein, we developed fibrous scaffolds of polycaprolactone (PC...
Thiolated poly(2-hydroxyethyl methacrylate) hydrogels as a degradable biocompatible scaffold for tissue engineering [0.03%]
用于组织工程的可降解生物相容性支架的含硫聚(2-羟乙基甲基丙烯酸酯)水凝胶
Hana Macková,Helena Hlídková,Zhansaya Kaberova et al.
Hana Macková et al.
Research of degradable hydrogel polymeric materials exhibiting high water content and mechanical properties resembling tissues is crucial not only in drug delivery systems but also in tissue engineering, medical devices, and biomedical-heal...
Large-pore-size Ti6Al4V scaffolds with different pore structures for vascularized bone regeneration [0.03%]
具有不同孔结构的大型孔径Ti6Al4V支架用于血管化骨再生
Chao Wang,Duoling Xu,Ling Lin et al.
Chao Wang et al.
Porous Ti6Al4V scaffolds are characterized by high porosity, low elastic modulus, and good osteogenesis and vascularization, which are expected to facilitate the repair of large-scale bone defects in future clinical applications. Ti6Al4V sc...
Development of electrospun mats based on hydrophobic hydroxypropyl cellulose derivatives [0.03%]
基于疏水性羟丙基纤维素衍生物的静电纺毡的开发研究
Sofia Saraiva,Patrícia Pereira,C T Paula et al.
Sofia Saraiva et al.
In this work, hydroxypropyl cellulose esters (HPCE) with long aliphatic chains were prepared and innovatively used in electrospinning to obtain hydroxypropyl cellulose (HPC)-based mats with enhanced resistance to moist environments. The des...