Delivery of coenzyme Q10 with mitochondria-targeted nanocarrier attenuates renal ischemia-reperfusion injury in mice [0.03%]
携带辅酶Q10的 mitochondria定位的纳米载体减轻了小鼠的肾缺血-再灌注损伤
Zhaohui Liu,Yan Li,Chunlei Li et al.
Zhaohui Liu et al.
Ischemia-reperfusion (I/R) injury causes high morbidity, mortality, and healthcare costs. I/R induces acute kidney injury through exacerbating the mitochondrial damage and increasing inflammatory and oxidative responses. Here, we developed ...
Fast dissolving nanofiber mat for the local antimicrobial application of roxithromycin in oral cavity [0.03%]
罗红霉素在口腔局部抗微生物快速溶解的纳米纤维网矩阵应用
Sungyun Kim,Jung-Jin Kim,Jae-Hyeon Jeong et al.
Sungyun Kim et al.
Fast disintegrating and dissolving nanofiber (NF) mat was devised to deliver roxithromycin for the treatment of the respiratory tract infection. NF membrane was made by an electrospinning process with poly(vinyl alcohol) (PVA), hydroxypropy...
Multifunctional polyethylene imine hybrids decorated by silica bioactive glass with enhanced mechanical properties, antibacterial, and osteogenesis for bone repair [0.03%]
具有增强力学性能，抗菌和成骨作用的硅生物玻璃修饰的聚乙烯亚胺杂化物用于骨修复
Mitra Aghayan,Parvin Alizadeh,Mozhgan Keshavarz
Mitra Aghayan
Inorganic/organic hybrids and bioactive glasses demonstrate promising potential as bone substitute biomaterials. A sol-gel hybrid consisting of silica bioactive glass and biodegradable polymer can combine the high bioactivity of a glass wit...
Mechanical properties, in vitro and in vivo biocompatibility analysis of pure iron porous implant produced by metal injection molding: A new eco-friendly feedstock from natural rubber (Hevea brasiliensis) [0.03%]
通过金属注射成型由天然橡胶(巴西橡胶树)生产纯铁多孔植入物的机械性能以及体内外生物相容性分析：一种新的环保材料来源
Diego Pacheco Wermuth,Thaís Casagrande Paim,Isadora Bertaco et al.
Diego Pacheco Wermuth et al.
Metal injection molding (MIM) has become an important manufacturing technology for biodegradable medical devices. As a biodegradable metal, pure iron is a promising biomaterial due to its mechanical properties and biocompatibility. In light...
Corrigendum to "Large-pore-size Ti6Al4V scaffolds with different pore structures for vascularized bone regeneration" [Mater. Sci. Eng. C. 131 (2021) 112499] [0.03%]
Corrigendum to "Large-pore-size Ti6Al4V scaffolds with different pore structures for vascularized bone regeneration" [Mater. Sci. Eng. C. 131 (2021) 112499]的勘误
Chao Wang,Duoling Xu,Ling Lin et al.
Chao Wang et al.
Design and synthesis of targeted star-shaped micelle for guided delivery of camptothecin: In vitro and in vivo evaluation [0.03%]
靶向树枝状大分子的设计与合成用于引导递送喜树碱：体内外评价
Mehrdad Sahranavard,Mahsa Shahriari,Khalil Abnous et al.
Mehrdad Sahranavard et al.
This study aimed to synthesize a star-shaped micelle using 3-azido-2,2-bis(azidomethyl)propan-1-ol (pentaerythritol triazide) core, as an initiator for the synthesis of three-arm polylactic acid (PLA) block. Then, the ends of the PLA arms w...
In-vitro effectiveness of poly-β-alanine reinforced poly(3-hydroxybutyrate) fibrous scaffolds for skeletal muscle regeneration [0.03%]
聚-β-丙氨酸增强的聚(3-羟基丁酸酯)纤维支架对骨骼肌再生的体外有效性研究
Elvan Konuk Tokak,Damla Çetin Altındal,Özge Ekin Akdere et al.
Elvan Konuk Tokak et al.
In skeletal muscle tissue engineering, success has not been achieved yet, since the properties of the tissue cannot be fully mimicked. The aim of this study is to investigate the potential use of poly-3-hydroxybutyrate (P3HB)/poly-β-alanin...
Quercetin loaded liposomes modified with galactosylated chitosan prevent LPS/D-GalN induced acute liver injury [0.03%]
载槲皮素脂质体修饰的壳聚糖乙酰化半乳糖在LPS/D-半乳糖胺诱导急性肝损伤中的保护作用研究
Xinbo Wei,Depeng Yang,Zheng Xing et al.
Xinbo Wei et al.
Quercetin (Que) has been proved to have various biological activities, including anti-oxidation, anti-inflammation and anti-virus, showing great potential in liver protection. However, its water insolubility leads to low bioavailability. Th...
On-demand pulling-off of magnetic nanoparticles from biomaterial surfaces through implant-associated infectious biofilms for enhanced antibiotic efficacy [0.03%]
通过植入相关感染生物膜从生物材料表面按需拉取磁性纳米粒子以提高抗生素疗效
Kecheng Quan,Zexin Zhang,Yijin Ren et al.
Kecheng Quan et al.
Biomaterial-associated infections can occur any time after surgical implantation of biomaterial implants and limit their success rates. On-demand, antimicrobial release coatings have been designed, but in vivo release triggers uniquely rela...
3D-printed alginate-hydroxyapatite aerogel scaffolds for bone tissue engineering [0.03%]
用于骨组织工程的3D打印海藻酸-羟基磷灰石气凝胶支架
Ana Iglesias-Mejuto,Carlos A García-González
Ana Iglesias-Mejuto
3D-printing technology allows the automated and reproducible manufacturing of functional structures for tissue engineering with customized geometries and compositions by depositing materials layer-by-layer with high precision. For these pur...