Mineralized polyplexes for gene delivery: Improvement of transfection efficiency as a consequence of calcium incubation and not mineralization [0.03%]
用于基因传递的矿化聚复合物：转染效率的提高是由于钙孵育而不是矿化造成的
Teo A Dick,Hasan Uludağ
Teo A Dick
Gene therapy is an emerging field in which nucleic acids are used to control protein expression. The necessity of delivering nucleic acids to specific cell types and intracellular sites demands the use of highly specialized gene carriers. A...
In vitro behavior of bioactive hybrid implant composed of additively manufactured titanium alloy lattice infiltrated with Mg-based alloy [0.03%]
由添加制造的钛合金晶格和Mg基合金组成的生物活性混合植入体的体外行为研究
Tohar Perets,Noa Ben Ghedalia-Peled,Razi Vago et al.
Tohar Perets et al.
We have developed a novel bioactive hybrid metallic implant that integrates the beneficial characteristics of a permanent matrix and a biodegradable substance. Such a combination may generate a material system that evolves into a porous str...
Polyanion-induced, microfluidic engineering of fragmented collagen microfibers for reconstituting extracellular environments of 3D hepatocyte culture [0.03%]
多阴离子诱导的微流体工程技术制造胶原蛋白微纤维碎片以重建三维肝细胞培养的细胞外环境
Rie Utoh,Sakiko Enomoto,Masumi Yamada et al.
Rie Utoh et al.
Artificial biological scaffolds made of extracellular matrix (ECM) components, such as type I collagen, provide ideal physicochemical cues to various cell culture platforms. However, it remains a challenge to fabricate micrometer-sized ECM ...
Construction of a TiO2/MoSe2/CHI coating on dental implants for combating Streptococcus mutans infection [0.03%]
用于对抗变形链球菌感染的种植体表面TiO2/MoSe2/CHI涂层构建方法研究
Maozhou Chai,Meiwen An,Xiangyu Zhang
Maozhou Chai
Infection and inflammation are the main causes resulting in the failure of dental implants. In this work, molybdenum diselenide (MoSe2) was synthesized hydrothermally on the surface of porous TiO2 coating prepared by micro-arc oxidation on ...
Efficient fabrication of stretching hydrogels with programmable strain gradients as cell sheet delivery vehicles [0.03%]
具有可编程应变梯度的拉伸水凝胶的高效制造作为细胞片传递载体
Rong Huang,Lirong Xu,Yan Wang et al.
Rong Huang et al.
Fabricating functional cell sheets with excellent mechanical strength for tissue regeneration remains challenging. Therefore, we devised a novel 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide/N-hydroxy-succinimide crosslinked hydrogel carr...
Early development of a polycaprolactone electrospun augment for anterior cruciate ligament reconstruction [0.03%]
用于前交叉韧带重建的聚ε-己内酯静电纺丝增强材料的早期开发
Luka Savić,Edyta M Augustyniak,Adele Kastensson et al.
Luka Savić et al.
Despite the clinical success of Anterior Cruciate Ligament reconstruction (ACLR) in some patients, unsatisfactory clinical outcomes secondary to graft failure are seen, indicating the need to develop new regeneration strategies. The use of ...
Influence of gellan gum-hydroxyapatite spongy-like hydrogels on human osteoblasts under long-term osteogenic differentiation conditions [0.03%]
长期骨生成分化条件下凝胶粒子-羟基磷灰石海绵样水凝胶对人成骨细胞的影响
Ana Raquel Bastos,F Raquel Maia,J Miguel Oliveira et al.
Ana Raquel Bastos et al.
The scientific community has been doing significant efforts towards engineering new 3D bone models in recent years. Osteocytes are mechanosensitive cells that play significant roles in the maintenance of bone homeostasis. Currently, as far ...
Phloroglucinol-enhanced whey protein isolate hydrogels with antimicrobial activity for tissue engineering [0.03%]
具有抗菌作用的香草朊隔离水凝胶在组织工程中的应用研究
Varvara Platania,Timothy E L Douglas,Mikhajlo K Zubko et al.
Varvara Platania et al.
Aging populations in developed countries will increase the demand for implantable materials to support tissue regeneration. Whey Protein Isolate (WPI), derived from dairy industry by-products, can be processed into hydrogels with the follow...
Enhanced spreading, migration and osteodifferentiation of HBMSCs on macroporous CS-Ta - A biocompatible macroporous coating for hard tissue repair [0.03%]
HBMSCs在宏孔CS-Ta上的扩散、迁移和成骨分化增强-一种适用于硬组织修复的生物相容性宏孔涂层
Junrong Tang,Hongyu Li,Mingxiao Guo et al.
Junrong Tang et al.
Macroporous tantalum (Ta) coating was produced on titanium alloy implant for bone repair by cold spray (CS) technology, which is a promising technology for oxygen sensitive materials. The surface characteristics as well as in vitro cytocomp...
Antibacterial and cell-friendly copper-substituted tricalcium phosphate ceramics for biomedical implant applications [0.03%]
具有抗菌性和生物相容性的可替代三钙磷酸盐陶瓷的铜及其在生物医学植入的应用
Inna V Fadeeva,Bogdan I Lazoryak,Galina A Davidova et al.
Inna V Fadeeva et al.
The development of new materials with antibacterial properties and the scope to decrease or eliminate the excessive antibiotic use is an urgent priority due to the growing antibiotic resistance-related mortalities. New bone substitute mater...