Novel tissue-engineered skin equivalent from recombinant human collagen hydrogel and fibroblasts facilitated full-thickness skin defect repair in a mouse model [0.03%]
重组人胶原蛋白水凝胶和成纤维细胞的新型组织工程皮肤等效物促进小鼠模型中全层皮肤缺损修复
Yayuan Guo,Zhengyue Bian,Qian Xu et al.
Yayuan Guo et al.
Tissue-engineered skin equivalent (TESE) is an optimized alternative for the treatment of skin defects. Designing and fabricating biomaterials with desired properties to load cells is critical for the approach. In this study, we aim to deve...
Poly(2-ethyl-2-oxazoline) functionalized reduced graphene oxide: Optimization of the reduction process using dopamine and application in cancer photothermal therapy [0.03%]
聚(2-乙基-2-噁唑啉)功能化的还原氧化石墨烯：使用多巴胺优化还原过程及其在癌症光热治疗中的应用
Rita Lima-Sousa,Cátia G Alves,Bruna L Melo et al.
Rita Lima-Sousa et al.
The high near infrared (NIR) absorption displayed by reduced graphene oxide (rGO) nanostructures renders them a great potential for application in cancer photothermal therapy. However, the production of this material often relies on the use...
Polycrystalline diamond coating on 3D printed titanium scaffolds: Surface characterisation and foreign body response [0.03%]
3D打印钛支架上的多晶钻石涂层：表面特征和异物反应
Marsilea A Booth,Leon Pope,Peter C Sherrell et al.
Marsilea A Booth et al.
Titanium-based implants are the leading material for orthopaedic surgery, due to their strength, versatility, fabrication via additive manufacturing and invoked biological response. However, the interface between the implant and the host ti...
FDA-approved bone grafts and bone graft substitute devices in bone regeneration [0.03%]
FDA批准的骨移植及骨移植替代物在骨再生中的应用
Cassidy E Gillman,Ambalangodage C Jayasuriya
Cassidy E Gillman
To induce bone regeneration there is a complex cascade of growth factors. Growth factors such as recombinant BMP-2, BMP-7, and PDGF are FDA-approved therapies in bone regeneration. Although, BMP shows promising results as being an alternati...
Near-infrared light-triggered synergistic antitumor therapy based on hollow ZIF-67-derived Co3S4-indocyanine green nanocomplex as a superior reactive oxygen species generator [0.03%]
近红外光触发的空心ZIF-67衍生Co3S4-亚甲基蓝纳米复合物作为优异氧自由基生成器的协同抗肿瘤治疗
Ying Jiang,Yi Lu,Lingli Lei et al.
Ying Jiang et al.
Reactive oxygen species (ROS) with strong oxidability have been considered as effective agents for antitumor therapy through oxidative damage to lipids, proteins, DNA and RNA. In this work, a multifunctional hollow cobaltosic sulfide (Co3S4...
Anti-tumour activity of Mg-6%Ag and Mg-10%Gd alloys in mice with inoculated melanoma [0.03%]
Mg-6%Ag和Mg-10%Gd合金在接种黑色素瘤的小鼠中的抗肿瘤作用
Natalia Anisimova,Mikhail Kiselevskiy,Natalia Martynenko et al.
Natalia Anisimova et al.
Cytotoxicity in vitro and anti-tumour activity in vivo of magnesium alloys Mg-6%Ag and Mg-10%Gd was studied. It was shown that specifically designed and thermomechanically processed Mg alloys produced a sizeable cytotoxic effect on PC-3 lin...
Dexamethasone-loaded, injectable pullulan-poly(ethylene glycol) hydrogels for bone tissue regeneration in chronic inflammatory conditions [0.03%]
用于慢性炎症条件下骨组织再生的可注射式充有地塞米松的戊聚糖-聚乙二醇水凝胶
Neelam Chauhan,Priya Gupta,Leena Arora et al.
Neelam Chauhan et al.
Chronic inflammation, infection, and fixation stability disrupts bone tissue regeneration by implants. The elevated levels of inflammatory markers and reactive oxygen species (ROS) damage tissues, inhibit osteoblastic differentiation, and p...
Ran He,Liguo Zhao,Vadim V Silberschmidt et al.
Ran He et al.
Background/motivation: Percutaneous femoropopliteal artery intervention moves towards personalised therapy, which requires design of unique lesion-specific stents. However, to date, not much progress has been made in the ...
Fatigue behaviour and biocompatibility of additively manufactured bioactive tantalum graded lattice structures for load-bearing orthopaedic applications [0.03%]
增材制造的活性钽梯度晶格结构的疲劳行为和生物相容性研究用于承重骨科应用
Wenliang Chen,Jingzhou Yang,Hui Kong et al.
Wenliang Chen et al.
Laser powder bed fusion (LPBF) additive manufacturing of pure tantalum and their graded lattice structures was systematically investigated, with emphasis on their microstructure evolution, phase formation, surface energy and biological prop...
Development of photo-crosslinkable collagen hydrogel building blocks for vascular tissue engineering applications: A superior alternative to methacrylated gelatin? [0.03%]
用于血管组织工程应用的光交联胶原水凝胶构建块的发展：甲基丙烯酰化明胶的更优替代品？
Nele Pien,Daniele Pezzoli,Jasper Van Hoorick et al.
Nele Pien et al.
The present work targets the development of collagen-based hydrogel precursors, functionalized with photo-crosslinkable methacrylamide moieties (COL-MA), for vascular tissue engineering (vTE) applications. The developed materials were physi...