Sarcoidosis related to checkpoint and BRAF/MEK inhibitors in melanoma [0.03%]
与检查点及BRAF/MEK抑制剂相关的恶性黑色素瘤肉芽肿性皮肤病病例报告
Manuel Rubio-Rivas,Catarina Moreira,J Marcoval
Manuel Rubio-Rivas
Therapy for advanced melanoma has deeply changed in the last decade with the introduction of checkpoint and BRAF/MEK inhibitors. Granulomatous reactions have been reported related to these drugs. We performed a systematic review of all the ...
Autoantibodies to stratify systemic sclerosis patients into clinically actionable subsets [0.03%]
自身抗体将系统性硬化病患者分为临床可操作亚组
Michael Mahler,Marie Hudson,Chelsea Bentow et al.
Michael Mahler et al.
Systemic sclerosis (SSc) is a rare chronic disease of unknown etiology characterized by vascular abnormalities and fibrosis involving the skin and internal organs, especially the gastrointestinal tract, lung, heart and kidneys. Although the...
Risk of scleroderma according to the type of immune checkpoint inhibitors [0.03%]
免疫检查点抑制剂的类型与硬皮病风险的关系
Benjamin Terrier,Sébastien Humbert,Laure-Hélène Preta et al.
Benjamin Terrier et al.
Introduction: Immune checkpoint inhibitors (ICIs) are associated with immune-related adverse events (irAEs). Among them, ICIs-induced systemic sclerosis (SSc) is poorly known. ...
Saeed Mohammadian Haftcheshmeh,Amir Abbas Momtazi-Borojeni
Saeed Mohammadian Haftcheshmeh
Hepatitis C virus- related cryoglobulinemic vasculitis: A review of the role of the new direct antiviral agents (DAAs) therapy [0.03%]
丙型肝炎病毒感染相关的冷球蛋白血症性血管炎：新型直接抗病毒药物(DAAs)治疗的作用回顾
Cesare Mazzaro,Luigino Dal Maso,Endri Mauro et al.
Cesare Mazzaro et al.
Hepatitis C virus (HCV) infection affects about 70 million people worldwide. HCV is responsible for both hepatitis and extra-hepatic manifestations. Chronic infection has been shown to develop in about 70% of cases and can progress to cirrh...
A new diagnostic algorithm for pattern-oriented autoantibody testing according to the ICAP nomenclature: A pilot study [0.03%]
一种新的模式导向自身抗体检测的诊断算法：一项基于ICAP命名法的试点研究
Maria Infantino,Teresa Carbone,Mariangela Manfredi et al.
Maria Infantino et al.
The commercial tests currently available as second-level tests to detect ANA sub-specificities are generally used independently from the ANA immunofluorescence (IIF) pattern. The aim of this study was to evaluate the efficacy of the use of ...
Francesca Angileri,Sébastien Legare,Antonella Marino Gammazza et al.
Francesca Angileri et al.
Immune checkpoint inhibitor-induced myositis, the earliest and most lethal complication among rheumatic and musculoskeletal toxicities [0.03%]
免疫检查点抑制剂诱导的肌炎是最先出现和最致命的风湿及肌肉骨骼毒性反应
Yves Allenbach,Céline Anquetil,Ali Manouchehri et al.
Yves Allenbach et al.
Background: In addition to restoring anti-tumor immune responses, immune checkpoint inhibitors (ICI) may also induce immune-related adverse events (irAE) that can affect any organ. We aim to determine the spectrum, timing...
Observational Study
Autoimmunity reviews. 2020 Aug;19(8):102586. DOI:10.1016/j.autrev.2020.102586 2020
Covid-19 and autoimmunity [0.03%]
新冠与自身免疫
Michael Ehrenfeld,Angela Tincani,Laura Andreoli et al.
Michael Ehrenfeld et al.
Rheumatic immune-related adverse events associated with cancer immunotherapy: A nationwide multi-center cohort [0.03%]
我国多中心大样本肿瘤免疫治疗相关风湿性免疫毒副反应特征分析
Janet Roberts,Daniel Ennis,Marie Hudson et al.
Janet Roberts et al.
Objective: Although immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, their use is associated with immune toxicities referred to as immune-related adverse events (irAE). Here we describe the clinical ...