Siddharth Maruvada,Frederick W Miller
Siddharth Maruvada
Over the past few decades, autoimmune diseases have seen a steady upsurge in global prevalence and associated costs. While the exact reasons for these increases are unknown, this trend has been attributed to increased exposure to environmen...
Mitochondrial transfer and transplantation in the immune cells: Mechanistic foundations, medical applications, and future prospects [0.03%]
免疫细胞中的线粒体转移和移植：机制基础、医学应用及未来前景
Xiaofeng Liu,Xinyu Feng,Deping Zhan et al.
Xiaofeng Liu et al.
Mitochondria exhibit tissue-specific physiological functions and are central to the maintenance of cellular homeostasis. Emerging evidence indicates that intercellular mitochondrial transfer is regulated by multiple determinants and exerts ...
Obstetric antiphospholipid syndrome: Advances in pathogenesis [0.03%]
抗磷脂综合征的发病机制新进展—— obstetric antiphospholipid syndrome: advances in pathogenesis -> 妊娠期抗磷脂综合征的发病机制新进展
Shumin Wang,Huimin Liu,Wanrong Huang et al.
Shumin Wang et al.
The publication of the 2023 ACR-EULAR classification criteria for antiphospholipid syndrome (APS) has shifted the understanding of APS from a "one-size-fits-all" approach to a more nuanced, subphenotype-based research and management paradig...
Points to consider for reporting digital ulcers in systemic sclerosis interventional studies: An initiative from the world Scleroderma Foundation digital ulcer ad hoc committee [0.03%]
系统性硬化症介入研究中报道数字溃疡需考虑的问题：世界系统性硬化症基金会数字溃疡临时委员会的倡议
Corrado Campochiaro,Nancy Maltez,Yossra Suliman et al.
Corrado Campochiaro et al.
Background: Digital ulcers (DUs) are among the most painful and functionally disabling complications of systemic sclerosis (SSc), affecting up to 50% of patients. Despite their clinical relevance, interventional studies o...
Hyaluronic acid fillers in systemic sclerosis and localized scleroderma: A systematic review [0.03%]
透明质酸填充物在系统性硬化症和局灶性硬皮病中的应用：系统综述
Arriana Gkouvi,Nektarios-Marios Liapis,Efterpi Zafiriou et al.
Arriana Gkouvi et al.
Introduction: Patients with systemic sclerosis (SSc) or morphea increasingly inquire about cosmetic procedures, as these conditions often result in disfiguring cutaneous manifestations such as microstomia, thin lips, scle...
Elevated lipid peroxidation biomarkers in autoimmune diseases: A systematic review and meta-analysis [0.03%]
自身免疫性疾病中脂质过氧化生物标志物升高的系统评价和.meta.分析
Yixiang Luo,Siqi Hua,Tongtong Song et al.
Yixiang Luo et al.
Background: Ferroptosis, an iron-dependent cell death pathway driven by lipid peroxidation (LPO), is implicated in the pathogenesis of autoimmune diseases (AIDs). However, comprehensive clinical evidence establishing the ...
Comment on "Meta-analysis of meteorological conditions and rheumatoid arthritis" [0.03%]
对“气象条件与类风湿性关节炎的荟萃分析”的评论
Feng Luo,Xueming Yao,Wukai Ma
Feng Luo
This correspondence addresses critical methodological limitations in the recent meta analysis by Hu et al. regarding meteorological conditions and rheumatoid arthritis (RA). We highlight issues of clinical heterogeneity arising from the con...
A SMURF2 p.T183M variant linking four autoimmune diseases through a fibrosis-prone immune endotype [0.03%]
SMURF2 p.T183M变异通过一种纤维化倾向性免疫表型连接四种自身免疫疾病
Jia Shi,Yiyun Pang,Li Zhang et al.
Jia Shi et al.
Autoimmunity in the era of immune checkpoint inhibitors: the evolving epidemiology of autoimmune diseases and the possible impact of COVID-19 [0.03%]
免疫检查点抑制剂时代的自身免疫性：自身免疫性疾病流行病学的新特点以及可能受到COVID-19的影响
Naim Mahroum,Abdulrahman Elsalti,Mohamed Alsharif et al.
Naim Mahroum et al.
Immune checkpoint inhibitors (ICIs) have markedly improved the prognosis of previously fatal malignancies, as evidenced by substantial gains in overall and progression-free survival in multiple clinical trials. The mechanism of action of IC...
Imaging the hidden player: Choroid plexus enlargement in multiple sclerosis [0.03%]
隐匿玩家的影像学研究：多发性硬化症中的脉络丛增大现象
Antonio Daniel Corlatescu,Horia Petre Costin,Gabriel González-Escamilla et al.
Antonio Daniel Corlatescu et al.
The choroid plexus (CP), one key regulator of cerebrospinal fluid (CSF) production and immune surveillance at the blood-CSF barrier, has recently emerged as a relevant structure in multiple sclerosis (MS) pathophysiology. This review synthe...