Pathogenic mechanisms of action of autoantibody-mediated central nervous system disorders targeting neuroglial surface antigens [0.03%]
针对神经胶质表面抗原的自身抗体介导的中枢神经系统疾病的致病作用机制
Magdalena Lerch,Sarosh R Irani,Sudarshini Ramanathan
Magdalena Lerch
Autoantibody-mediated diseases targeting central nervous system antigens are increasingly recognised and may manifest as encephalitis or demyelination. A subset of these diseases can be associated with autoantibodies targeting neuronal or g...
Immune rehabilitation after renal transplantation in autoimmune diseases: Balancing immunosuppression and risk of complications [0.03%]
自身免疫性疾病患者肾移植后的免疫康复：平衡免疫抑制和并发症风险的关系
Fatima Alnaimat,Ayman AbuHelal,Reem Elmusa et al.
Fatima Alnaimat et al.
Autoimmune kidney diseases represent a major etiology of chronic kidney disease and often result in end-stage kidney disease (ESKD), in which renal transplantation offers better survival and quality of life as compared to extended dialysis....
Clinical characteristics and cancer risk of anti-OJ antisynthetase syndrome: A cohort comparative study and a systematic literature review [0.03%]
抗OJ型合成酶抗体综合征的临床特征及肿瘤风险：队列比较研究与系统文献回顾
Valentin Pillot,Segolene Toquet,Jean Luc Charuel et al.
Valentin Pillot et al.
Background: Antisynthetase syndrome (ASyS) is a systemic autoimmune disease that primarily affects the lungs, joints, and muscles, and is associated in over 90% of cases with anti-Jo-1, anti-PL7, or anti-PL12 antibodies. ...
Precision immunotherapies for systemic lupus erythematosus: From pathogenic targets to translational horizons [0.03%]
系统性红斑狼疮的精准免疫治疗：从治病靶点到转化前景
Chenjing Guo,Zuqing Lei,Leyan Zhao et al.
Chenjing Guo et al.
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disorder in which aberrant B-cell activation, persistent autoantibody production, and dysregulated cytokine and intracellular signaling networks converge to produce relapsing-...
Epidemiology of eosinophilic granulomatosis with polyangiitis in northern Spain: A population-based study (2000-2024) and literature review [0.03%]
西班牙北部颗粒细胞血管炎的流行病学研究（2000-2024）及文献回顾
Fabricio Benavides-Villanueva,Diana Prieto-Peña,Vanesa Calvo-Río et al.
Fabricio Benavides-Villanueva et al.
Objective: Eosinophilic granulomatosis with polyangiitis (EGPA) is an ANCA-associated vasculitis. Epidemiological data remain limited and vary considerably across regions and time periods, partly due to differences in stu...
Unraveling the role of human endogenous retroviruses in rheumatoid arthritis [0.03%]
人类内源性逆转录病毒在类风湿关节炎中作用的探讨
Susana Castaño,Tulio J Lopera,Marlén Martínez et al.
Susana Castaño et al.
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic and painful joint inflammation that can lead to bone erosion and significant disability if not treated promptly. The etiology of this disease is not fully d...
Exploring the metabolic mysteries: Mechanistic insights into lactylation-mediated regulation of autoimmune diseases [0.03%]
探索代谢奥秘：从机制上深入了解乳酰化介导的自身免疫疾病调控
Nan Kang,Bo Wang,Yunjia Li et al.
Nan Kang et al.
Autoimmune diseases are chronic disorders caused by the immune system's aberrant recognition and attack of self-tissues. Accumulating evidence has revealed that these diseases are closely related to metabolic reprogramming and epigenetic re...
Vagus nerve stimulation in autoimmune diseases: Mechanisms, therapeutic potential, and clinical applications [0.03%]
自主神经刺激在自身免疫性疾病中的机制、治疗潜力和临床应用
Junhe Ye,Yitian Lan,Wenmi Li et al.
Junhe Ye et al.
Autoimmune diseases characterized by dysregulated immune responses against self-antigens. Current pharmacotherapies are limited by like resistance, side effects, and high costs, highlighting the need for novel interventions. Vagus nerve sti...
Fatima Alnaimat,Abdel Rahman Feras AlSamhori,Birzhan Seiil et al.
Fatima Alnaimat et al.
The digitization of research has transformed how evidence is gathered, hypotheses are generated, and manuscripts are written, introducing ethical challenges related to plagiarism, authorship, and artificial intelligence (AI) in medical writ...
Enthesitis in Spondyloarthritis. From pathogenesis to clinical presentation and imaging: Similarities and differences between PsA and axSpA [0.03%]
附着点炎的病理、临床及影像特点：银屑病关节炎与强直性脊柱炎的比较
Ioannis Xynogalas,Anastasios Karamanakos,Artemis Galani et al.
Ioannis Xynogalas et al.
Radiographic axial spondyloarthritis (r-axSpA), non-radiographic axial spondyloarthritis (nr-axSpA), and psoriatic arthritis (PsA) represent distinct yet overlapping entities within the spondyloarthritis (SpA) spectrum. Enthesitis has emerg...