Combination targeted therapy with two biologic/targeted synthetic DMARDs in 1200 patients with immune mediated inflammatory diseases. A systematic literature review for current landscape in safety and efficacy [0.03%]
生物制剂/靶向合成DMARDs联合治疗在1200例免疫介导性炎症性疾病患者中的应用：系统文献回顾以评估其当前疗效及安全性格局
Angeliki Zoi Lignou,Konstantinos D Vassilakis,Xenofon Baraliakos et al.
Angeliki Zoi Lignou et al.
Background: Immune-mediated inflammatory diseases (IMID) include rheumatoid arthritis (RA), psoriatic arthritis (PsA), axial spondyloarthritis (axSpA), Crohn's disease (CD), ulcerative colitis (UC), and psoriasis (PsO). W...
Glucagon-Like Peptide-1 (GLP-1) receptor agonists in rheumatology: A review of current evidence and future directions [0.03%]
胰高血糖素样肽-1(GLP-1)受体激动剂在风湿病学中的应用：现有证据和未来方向的回顾
Emre Bilgin,Vincenzo Venerito,Dimitrios P Bogdanos
Emre Bilgin
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have improved the management of type 2 diabetes and obesity. Increasing evidence suggests their potential therapeutic role in rheumatic and musculoskeletal diseases, yet their precise me...
Epidemiological patterns and in-hospital mortality in ANCA-associated vasculitis: Insights from Spain's National Health Data (2016-2022) [0.03%]
西班牙国家健康数据（2016-2022）中的ANCA相关性血管炎的流行病学模式和住院死亡率
Francisco-Josué Cordero-Pérez,Pablo Martínez-Rodríguez,Luis Arribas-Pérez et al.
Francisco-Josué Cordero-Pérez et al.
Background: ANCA-associated vasculitis (AAV), including granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA), is a systemic autoimmune disease. T...
The efficacy and safety of monoclonal anti-TNF antibodies in the treatment of vascular Behçet's syndrome: A systematic review and meta-analysis [0.03%]
抗肿瘤坏死因子单克隆抗体治疗血管型贝赫切特综合征疗效和安全性的系统评价和meta分析
Yeling Liu,Jingwen Wu,Yiyuan Ao et al.
Yeling Liu et al.
Objectives: This study is the first meta-analysis to evaluate the efficacy and safety of monoclonal anti-TNF antibodies in patients with vascular Behçet's syndrome (VBS). ...
Infectious agents in dilated cardiomyopathy: Genetic interactions, autoimmunity, mechanisms, and therapeutic approaches [0.03%]
扩张型心肌病中的感染因子：基因互作、自身免疫、机制及治疗策略
Jingdi Zhang,Haoting Zhan,Honglin Xu et al.
Jingdi Zhang et al.
Dilated cardiomyopathy (DCM) is a heterogeneous myocardial disorder characterized by left ventricular dilation and systolic dysfunction in the absence of ischemic, hypertensive, or valvular heart disease. Although its precise etiology remai...
Mesenchymal stem cell in immunomodulation of dendritic cells: Implications for inflammatory bowel disease therapy [0.03%]
间充质干细胞通过调节树突细胞的免疫作用治疗炎症性肠病
Dongqin Song,Change He,Dickson Kofi Wiredu Ocansey et al.
Dongqin Song et al.
Inflammatory bowel disease (IBD) is a highly prevalent and recurrent autoimmune disorder characterized by dysregulation of the immune system leading to intestinal inflammation. Currently, available clinical treatments, such as mesalazine, a...
Chimeric antigen receptor cell therapy: A revolutionary approach transforming cancer treatment to autoimmune disease therapy [0.03%]
嵌合抗原受体细胞治疗：从癌症治疗到自身免疫性疾病疗法的革命性策略
Ruifan Wen,Binbin Li,Feifeng Wu et al.
Ruifan Wen et al.
Currently, autoimmune disorders are predominantly managed with broad-spectrum immunosuppressive agents and monoclonal antibodies, which can alleviate disease symptoms but are rarely curative and are frequently associated with significant ad...
Impact and management of warm autoimmune haemolytic anaemia associated with systemic lupus erythematosus [0.03%]
与系统性红斑狼疮相关的温抗体型自身免疫性溶血性贫血的临床分析及治疗体会
Guillermo J Pons-Estel,Marta Mosca,Daniel J Wallace et al.
Guillermo J Pons-Estel et al.
Warm autoimmune haemolytic anaemia (wAIHA) is a rare autoantibody-mediated disorder that may occur in association with systemic lupus erythematosus (SLE). The clinical course of wAIHA is highly variable, ranging from anaemia compensated ade...
Radio-labelled fibroblast activation protein inhibitors in interstitial lung diseases - a systematic review [0.03%]
放射性标记的成纤维细胞活化蛋白抑制剂在间质性肺病中的应用-系统评价
Mads Bundgaard Nielsen,Rikke Helin Johnsen,Jann Mortensen et al.
Mads Bundgaard Nielsen et al.
Background: Currently, no tools can monitor ongoing fibrotic activity properly, making early identification of and timely therapeutic intervention with antifibrotics in patients with progressive fibrosing interstitial lun...
Advancing research on regulatory autoantibodies targeting GPCRs: Insights from the 5th international symposium [0.03%]
第五届GPCR调节自身抗体研究国际研讨会进展报告
Otavio Cabral-Marques,Lena F Schimke,Guido Moll et al.
Otavio Cabral-Marques et al.
The 5th International Symposium on Regulatory Autoantibodies Targeting GPCR (RAB-GPCRs) advanced the understanding of the significant role played by autoantibodies targeting G-protein-coupled receptors (GPCRs) in various human diseases. Onc...