B cells in systemic lupus erythematosus: from pathogenic mechanisms to targeted therapies [0.03%]
系统性红斑狼疮中的B细胞：从病理机制到靶向治疗
Xu Su,Qingqiang Lei,Xuerui Chen et al.
Xu Su et al.
Systemic lupus erythematosus (SLE) is a multisystem autoimmune condition characterized by a pronounced female predilection, particularly during reproductive age, and poses a significant threat to health and survival. A defining pathological...
Nintedanib combined with dual immunosuppression for interstitial lung disease in systemic sclerosis and rheumatoid arthritis: A systematic review and pooled multicentre real-world cohort study [0.03%]
尼达尼布联合双重免疫抑制治疗系统性硬化和类风湿关节炎间质性肺病：系统评价及多中心真实世界队列研究
Anastasia Chioni,Corrado Campochiaro,Shiri Keret et al.
Anastasia Chioni et al.
Interstitial lung disease (ILD) in patients with systemic sclerosis (SSc) or rheumatoid arthritis (RA) carries substantial mortality, and treatment options remain limited. We investigated the effectiveness, safety, and tolerability of tripl...
Double-negative T cells in systemic lupus erythematosus: From immunopathology to therapeutic target [0.03%]
系统性红斑狼疮中的双阴性T细胞：从免疫病理到治疗靶点
Yuhui Zhao,Xiaoyang Liu,Nan Li et al.
Yuhui Zhao et al.
Systemic lupus erythematosus (SLE) is an autoimmune disease marked by diverse clinical manifestations and profound immune dysregulation. Among the immune cells implicated in SLE pathogenesis, double-negative T (DNT) cells, a unique subset o...
Diagnosis, treatment and monitoring of chronic nonbacterial osteomyelitis (CNO) and chronic recurrent multifocal osteomyelitis (CRMO) - Evidence, practice and consensus-based recommendations from the German pediatric rheumatology society (GKJR) [0.03%]
慢性非细菌性骨髓炎(CNO)和慢性复发性多发性骨髓炎(CRMO)的诊断、治疗及监测：来自德国儿科风湿病学会的循证、实践与共识建议
A Schnabel,C Reiser,M Beer et al.
A Schnabel et al.
Background: Chronic nonbacterial osteomyelitis (CNO), sometimes also referred to as chronic recurrent multifocal osteomyelitis (CRMO), is a rare autoinflammatory bone disease primarily affecting children and adolescents. ...
SpA in animal models: Unraveling the duality of inflammation and bone formation [0.03%]
动物模型中的SpA：揭示炎症和骨形成的二元性
Stéphane Hilliquin,Nicolas Rosine,Rik Lories et al.
Stéphane Hilliquin et al.
Spondyloarthritis (SpA) comprises a heterogeneous group of chronic inflammatory rheumatic diseases affecting the axial skeleton, peripheral joints, and entheses. It is uniquely characterized by the coexistence of inflammation and pathologic...
Inflammatory biomarkers of atherosclerosis in SLE that may improve SLE-specific cardiovascular risk assessment tools [0.03%]
可能改善SLE特异性心血管风险评估工具的动脉粥样硬化的炎症生物标志物
Silvia De Santis,Marcella Prete,Patrizia Leone et al.
Silvia De Santis et al.
Cardiovascular (CV) events (CVE) are a leading cause of morbidity and mortality in systemic lupus erythematosus (SLE), and affected patients display a two- to three-fold higher risk than the general population. This increased CV risk remain...
Yujiao Wei,Jian Zheng,Miao Tu et al.
Yujiao Wei et al.
Systemic lupus erythematosus (SLE) is a persistent autoimmune condition involving multiple organ systems. It is fundamentally driven by the dysregulation of the immune system. Under this condition, the immune system erroneously targets body...
Serious infections in antineutrophil cytoplasmic antibody-associated vasculitis: Epidemiology, risk factors, and strategies for prevention [0.03%]
抗中性粒细胞胞浆抗体相关性血管炎的严重感染：流行病学、危险因素及预防策略
Bryan Chang,Duvuru Geetha,David R W Jayne et al.
Bryan Chang et al.
Serious infections in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) represent a contributor to morbidity and mortality. Patients are susceptible to both typical and opportunistic infections due to immunocompromise...
The application of low-carbohydrate diet in autoimmune diseases: Mechanisms, evidence, and prospects for clinical translation [0.03%]
低碳水化合物饮食在自身免疫性疾病中的应用：机制、证据及临床转化前景
Ming-Fu Lu,Xiang-Yu Qi,Jing-Wen Cheng et al.
Ming-Fu Lu et al.
Emerging evidence suggests that low-carbohydrate diet (LCD) may exert beneficial effects across multiple autoimmune diseases (AIDs), yet their underlying mechanisms remain insufficiently elucidated and clinical evidence is still limited. Th...
Gunnar Houen
Gunnar Houen
Immunodeficiencies can be grouped into genetically inherited (primary immunodeficiencies), somatic mutation-acquired (secondary genetic immunodeficiencies) and environmentally acquired (secondary immunosuppressions). Such immunodeficiencies...