Autoimmune encephalitis-associated epilepsy with glutamic acid decarboxylase autoantibodies and type 1 diabetes mellitus: A comprehensive systematic scoping review of a clinical syndrome [0.03%]
与谷氨酸脱羧酶自身抗体相关联的自身免疫性脑炎癫痫及1型糖尿病：一种临床综合征的全面系统综述
Mohsen Farjoud Kouhanjani,Alina Plautz,Nico Melzer et al.
Mohsen Farjoud Kouhanjani et al.
Background: Type 1 diabetes mellitus (T1DM) and autoimmune neurological syndromes (AINS), including autoimmune encephalitis-associated epilepsy/seizures (AEAE/S), share immune-mediated mechanisms linked to glutamic acid d...
Hydroxychloroquine and teratogenic risk in pregnancy in systemic autoimmune diseases: A systematic narrative review [0.03%]
羟基氯喹和自身免疫性疾病孕期致畸风险的系统综述
Enrique Esteve-Valverde,Francesc Miro-Mur,Ariadna Anunciacion-LLunell et al.
Enrique Esteve-Valverde et al.
Background: Hydroxychloroquine (HCQ) is increasingly prescribed during pregnancy to manage systemic autoimmune diseases (SAD) such as systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). Its use has bee...
Chimeric antigen receptor-based cellular therapy in autoimmune diseases: A systematic review and meta-analysis of clinical, serological and safety outcomes [0.03%]
基于嵌合抗原受体的细胞疗法在自身免疫性疾病中的应用：临床、血清学和安全性结果的系统评价与meta分析
Hon Jen Wong,Ainsley Ryan Yan Bin Lee,Qai Ven Yap et al.
Hon Jen Wong et al.
Objective: Chimeric antigen receptor (CAR)-T cell and natural killer cell therapies are emerging as treatments for autoimmune diseases (AIDs), capable of inducing immune reprogramming and drug-free remission. Their effica...
Fatty acid oxidation and inflammatory bowel disease: Highlighting the roles of pathogenesis and treatment [0.03%]
脂肪酸氧化与炎症性肠病：突显病理和治疗作用
Chunyan Li,Jun Shen
Chunyan Li
The increasing prevalence of inflammatory bowel disease (IBD) imposes a substantial economic burden, and its pathogenesis is associated with dietary fat intake. Short-chain fatty acids (SCFAs) regulate intestinal inflammation and immunity b...
Mepolizumab for eosinophilic granulomatosis with polyangiitis (EGPA): A scoping review of effectiveness and safety data derived from real-world evidence [0.03%]
米波利珠单抗治疗嗜酸性肉芽肿伴聚动脉炎（EGPA）：关于有效性和安全性的真实世界数据的范畴综述
Íñigo Rúa-Figueroa,Beatriz Velasco,Maria C Cid
Íñigo Rúa-Figueroa
Background: Management of eosinophilic granulomatosis with polyangiitis (EGPA) is challenging due to inconsistent responses and frequent relapses with classic treatments. Mepolizumab (MPZ), an anti-interleukin-5 monoclona...
Long-term outcomes and prognostic factors in juvenile dermatomyositis: A systematic review of studies with more than 12 months of follow-up [0.03%]
少年皮肌炎长期结局及预后因素的系统评价研究——为期12个月以上的队列研究
Laura Scagnellato,Christina Kostopoulou,Ramonda Roberta et al.
Laura Scagnellato et al.
Background: Juvenile dermatomyositis (JDM) is a rare autoimmune myopathy in children and young people (CYP), with long-term outcomes that remain poorly defined. We systematically reviewed long-term studies to summarise ou...
Annexin A1 and its membrane receptor complex: Implications for immune regulation and autoimmune disease mechanisms [0.03%]
annexin a1及其膜受体复合物：对免疫调控及自身免疫病机制的意义
Thrupthi Ambrish,Pavan K Jayaswamy,Vikram Haridas et al.
Thrupthi Ambrish et al.
Annexin A1 (AnxA1) is a key anti-inflammatory mediator that regulates both innate and adaptive immunity, promoting resolution of inflammation and tissue repair. It is highly expressed in neutrophils, macrophages, dendritic cells, and select...
Metabolic signatures in systemic autoimmune diseases: A state-of-the-art overview of systemic lupus erythematosus, primary Sjögren's syndrome, and systemic sclerosis [0.03%]
自身免疫性疾病中的代谢特征：系统性红斑狼疮、原发性干燥综合征和系统性硬化症的最新概述
Artur Jędreas,Sylwia Michorowska,Sébastien Le Jan et al.
Artur Jędreas et al.
Systemic lupus erythematosus (SLE), primary Sjögren's syndrome (pSS), and systemic sclerosis (SSc) are systemic autoimmune diseases characterized by marked heterogeneity in clinical presentation, organ involvement, and disease course. Thei...
The rituximab paradox in rheumatoid arthritis: Re-evaluating B-cell depletion depth and the synovial microenvironment [0.03%]
利妥昔单抗治疗类风湿关节炎的悖论：重新评估B细胞耗竭深度与滑膜微环境的关系
Cheng Chen,Wenting Luo
Cheng Chen
Background: Two decades after B-cell depletion altered the therapeutic landscape of rheumatoid arthritis (RA), a clinical paradox persists. Pharmaceutical engineering has yielded advanced anti-CD20 agents (ocrelizumab, of...
Enteropathy in STAT3 GOF syndrome: Insights into the role of the JAK/STAT pathway [0.03%]
STAT3 功能获得性综合征的肠病：JAK/STAT 信号通路作用的新见解
C Caranfil,M Crepaldi,A Marzollo et al.
C Caranfil et al.
The term enteropathy refers to any disease affecting the small intestine. In the past, celiac disease (CeD) was the only well-established atrophic enteropathy, but the spectrum of non-celiac enteropathies with villous atrophy has been expan...