Immunomodulation for accelerated atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus [0.03%]
风湿和系统性红斑狼疮中免疫调节与动脉粥样硬化的关系研究
Elena Bartoloni,Fabio Cacciapaglia,Gian Luca Erre et al.
Elena Bartoloni et al.
In the last decades, consisting evidence supported a close relationship between both innate and adaptive immune systems and the accelerated cardiovascular (CV) disease characterizing autoimmune diseases, such as systemic lupus erythematosus...
Differences in clinical phenotype, laboratory, and imaging manifestations between AQP4 IgG positive and AQP4 MOG IgG double negative NMOSD: How to correctly diagnose the two [0.03%]
AQP4 IgG阳性与AQP4及MOG IgG双阴性NMOSD的临床表型、实验室和影像特点差异：如何正确诊断两种类型患者
Fengna Chu,Mingchao Shi,Jie Zhu
Fengna Chu
Neuromyelitis optica spectrum disorders (NMOSD) is an uncommon autoimmune inflammatory demyelinating disorder of the central nervous system (CNS) and causes severe disability and even death. Aquaporin-4 immunoglobulin G (AQP4-IgG) antibody ...
The role of memory T cells in type 1 diabetes: Phenotypes, mechanisms, and therapeutic implications [0.03%]
记忆T细胞在1型糖尿病中的作用：表型、机制和治疗意义
Pooria Fazeli,Shiva Abolhasani,Negin Karamali et al.
Pooria Fazeli et al.
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the loss of insulin-producing cells in the pancreatic islets. Patients with T1D have autoreactive CD4+ and CD8+ T cells that show specific features, indicating previous ...
Neuropsychiatric manifestations in systemic lupus erythematosus and Sjogren's disease [0.03%]
系统性红斑狼疮和舍格伦综合征的精神神经表现
Amanda Carolina Miranda Costa,Diego de Paula Ferreira Nunes,Paulo Rogério Júlio et al.
Amanda Carolina Miranda Costa et al.
Introduction: Autoimmune diseases often present in a systemic manner, affecting various organs and tissues. Involvement of the central and peripheral nervous system is not uncommon in these conditions and is associated wi...
CD4+CD8+ double-positive T cells in immune disorders and cancer: Prospects and hurdles in immunotherapy [0.03%]
共阳性T细胞在免疫性疾病和癌症中的作用：免疫治疗的前景与挑战
Md Rakibul Alam,Amos Olalekan Akinyemi,Jianlin Wang et al.
Md Rakibul Alam et al.
CD4+ and CD8+ T cells play critical roles in both innate and adaptive immune responses, managing and modulating cellular immunity during immune diseases and cancer. Their well-established functions have led to significant clinical benefits....
Ying Zhang,Chenyang Zang,Manyun Mao et al.
Ying Zhang et al.
Autoimmune diseases (ADs) are a group of complex, chronic conditions characterized by disturbance of immune tolerance, with examples including systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, and psoriasis. These dise...
Disease-modifying strategies: Targeting protein kinases in multiple sclerosis and other autoimmune disorders [0.03%]
针对多发性硬化症和其他自身免疫性疾病中的蛋白激酶的疾病修正疗法
Franz Felix Konen,Nora Möhn,Torsten Witte et al.
Franz Felix Konen et al.
A wide variety of immunomodulatory therapies are already available for the treatment of multiple sclerosis (MS). Through fundamental insights from basic research with a gain of knowledge in the pathological processes underlying MS, the expl...
Luz P Blanco,Noemi Salmeri,Sarah M Temkin et al.
Luz P Blanco et al.
Endometriosis is a female-specific chronic condition that affects 1 in 10 women and other individuals with a uterus worldwide with common symptoms that include pelvic pain and infertility. Reliable and effective non-invasive biomarkers for ...
Maternal and fetal outcomes in Latin American SLE pregnancies: A systematic review and meta-analysis [0.03%]
南美狼疮妊娠的母婴结局：系统性回顾和荟萃分析
Jairo Cajamarca-Baron,Catalina Sanmiguel-Reyes,Juan Esteban Bedoya-Loaiza et al.
Jairo Cajamarca-Baron et al.
Introduction: Systemic lupus erythematosus (SLE) predominantly affects women, especially during their reproductive years, leading to increased risks during pregnancy. Latina women develop SLE at a younger age, which incre...
Chiara Marvisi,Federica Macaluso,Caterina Ricordi et al.
Chiara Marvisi et al.
Giant cell arteritis (GCA), also known as temporal arteritis, is the most common form of vasculitis in the elderly. While initially described as involving the temporal arteries, GCA can also affect the aorta and its major branches. Despite ...