Efficacy, safety, and tolerability of antifibrotic agents in rheumatoid arthritis-associated interstitial lung disease: A systematic review and meta-analysis [0.03%]
抗纤维化药物在类风湿性关节炎相关间质性肺疾病中的疗效、安全性和耐受性的系统评价和荟萃分析
Javier Narváez,Martí Aguilar-Coll,Montserrat Roig-Kim et al.
Javier Narváez et al.
Objective: To evaluate the efficacy, safety, and tolerability of antifibrotic agents, nintedanib and pirfenidone, in the treatment of rheumatoid arthritis-associated interstitial lung disease (RA-ILD). ...
Research progress on estrogen and estrogen receptors in the occurrence and progression of autoimmune thyroid diseases [0.03%]
雌激素和雌激素受体在自身免疫性甲状腺疾病发生发展中的研究进展
Jiewen Xie,Jie Wang,Xuejiao Cui
Jiewen Xie
Autoimmune thyroid disease (AITD) is a category of disease related to sex differences, with a significantly higher incidence in women than in men. In addition to X chromosome inactivation abnormalities, Estrogen and estrogen receptors may l...
SLE patients with childhood-onset: A nation-wide population-based study [0.03%]
儿童发病的SLE患者：一项全国性基于人群的研究
Alexandra Kachaner,Arthur Mageau,Jean-François Timsit et al.
Alexandra Kachaner et al.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that typically affects women of childbearing age. Using a nationwide database, we aimed to assess the prevalence, main clinical features and outcomes of patients with childh...
Association between breastfeeding and the risk of autoimmune diseases: A systematic review and meta-analysis [0.03%]
母乳喂养与自身免疫性疾病风险之间的相关性：系统评价和荟萃分析
Wen-Jie Li,Yue-Can Gao,Xiao Hu et al.
Wen-Jie Li et al.
Objectives: Previous studies on the association between breastfeeding and autoimmune diseases risk have yielded inconsistent findings. This study employed a systematic review and meta-analysis to explore the effect of bre...
Effects of nutritional supplements and dietary interventions on rheumatoid arthritis: An umbrella review of meta-analyses of randomized controlled trials [0.03%]
营养补充剂和饮食干预对类风湿关节炎的影响：随机对照试验荟萃分析的伞式回顾
Xue-Er Cheng,Xiao Hu,Jian Tang et al.
Xue-Er Cheng et al.
Backgrounds: The effects of nutritional supplements and dietary interventions on rheumatoid arthritis (RA) are still unclear. Objectives: ...
Pedro Carneiro,Manuel M Vicente,Maria Isabel Leite et al.
Pedro Carneiro et al.
Regulatory T cells (Tregs) have a key role in the maintenance of immune tolerance and in the prevention of autoimmunity. Recent studies have shown an association between decreased Treg frequency and a deficient suppressive activity with the...
Epigenetics in autoimmune diseases: Unraveling the hidden regulators of immune dysregulation [0.03%]
自身免疫疾病中的表观遗传学：揭示免疫失调的隐藏调节因子
Giacomo Bagni,Edoardo Biancalana,Emanuele Chiara et al.
Giacomo Bagni et al.
Autoimmune diseases result from complex interactions between genetic and environmental factors. Recent advances in epigenetic research shed light on the intricate regulatory mechanisms that contribute to the development and progression of s...
The immune system in Hashimoto's thyroiditis: Updating the current state of knowledge on potential therapies and animal model construction [0.03%]
桥本甲状腺炎中的免疫系统：关于潜在疗法和动物模型构建的最新知识更新
Ruixi Li,Ting He,Zhichao Xing et al.
Ruixi Li et al.
Hashimoto's thyroiditis (HT) is one of the most prevalent endocrine disorders worldwide, and it can occur in people of all ages, including children. HT has a multifactorial pathogenesis and develops after a combination of gene regulation, e...
Beyond circulating B cells: Characteristics and role of tissue-infiltrating B cells in systemic sclerosis [0.03%]
循环B细胞以外：系统性硬化症中组织浸润B细胞的特征及作用
Mathilde Le Maître,Thomas Guerrier,Sébastien Sanges et al.
Mathilde Le Maître et al.
B cells play a key role in the pathophysiology of systemic sclerosis (SSc). While they are less characterized than their circulating counterparts, tissue-infiltrating B cells may have a more direct pathological role in tissues. In this revi...
Cell type-specific regulation of the pentose phoshate pathway during development and metabolic stress-driven autoimmune diseases: Relevance for inflammatory liver, renal, endocrine, cardiovascular and neurobehavioral comorbidites, carcinogenesis, and aging [0.03%]
在发育和代谢压力驱动的自身免疫性疾病中五碳糖磷酸途径的细胞类型特异性调控：对于炎症性肝肾内分泌心血管和神经行为共病，致癌作用和衰老的相关性
Katalin Banki,Andras Perl
Katalin Banki
The pathogenesis of autoimmunity is incompletely understood which limits the development of effective therapies. New compelling evidence indicates that the pentose phosphate pathway (PPP) profoundly regulate lineage development in the immun...