Cochlear T cells and their role in health and disease: A systematic review [0.03%]
耳蜗T细胞及其在健康和疾病中的作用：系统性综述
Evi De Backer,Dorien Verdoodt,Peter Ponsaerts et al.
Evi De Backer et al.
Background: The role of T cells in health and disease has already been studied extensively in many organs, yet their activity in the cochlea and involvement in hearing loss remains less explored. This review aims to summa...
Molecular/antigenic mimicry and immunological cross-reactivity explains SARS-CoV-2-induced autoimmunity [0.03%]
分子/抗原模拟和免疫交叉反应可解释SARS-CoV-2诱导的自身免疫反应
Yekbun Adiguzel,Dimitros P Bogdanos,Yehuda Shoenfeld
Yekbun Adiguzel
COVID-19 pandemic is over, but its effects on chronic illnesses remain a challenging issue. Understanding the influence of SARS-COV-2-mediated autoimmunity and overt autoimmune disease is of paramount importance, as it can provide a critica...
The impact of pregnancy on future health in Rheumatoid Arthritis: A systematic review of the literature [0.03%]
妊娠对类风湿性关节炎患者未来健康影响的文献系统回顾
Bethan Goulden,George Woodward,Sophie Leiner et al.
Bethan Goulden et al.
Objectives: To assess whether obstetric history predicts future rheumatoid arthritis (RA) diagnosis, severity, and/or maternal health beyond the immediate postpartum period. ...
Emerging roles of mechanically activated ion channels in autoimmune disease [0.03%]
机械激活离子通道在自身免疫疾病中的新角色
Zhiru Zeng,Engeng Chen,Jing Xue
Zhiru Zeng
Mechanically activated (MA) ion channels have rapidly gained prominence as vital conduits bridging aberrant mechanical cues in tissues with the dysregulated immune responses at the core of autoimmune diseases. Once regarded as peripheral pl...
The burden of extracutaneous manifestations in juvenile localized scleroderma: A literature review [0.03%]
局灶性硬皮病外皮肤表现的负担：文献综述
Ilaria Liguoro,Gabriele Simonini,Giorgia Martini
Ilaria Liguoro
Objectives: Juvenile Localized Scleroderma (JLS) is an autoimmune disease leading to fibrosis of skin and subcutaneous tissues affecting children, that is characterized by extracutaneous manifestations (ECM) in about 20 %...
Lupus nephritis trials network (LNTN) repeat kidney biopsy-based definitions of treatment response: A systematic literature review-based proposal [0.03%]
狼疮性肾炎试验网络(LNTN)基于重复肾脏活检的治疗反应定义：基于系统文献回顾的建议
Ioannis Parodis,Nursen Cetrez,Leonardo Palazzo et al.
Ioannis Parodis et al.
Within the frame of the Lupus Nephritis Trials Network (LNTN), we conducted a systematic literature review (SLR) to propose kidney tissue-based definitions of treatment outcomes in lupus nephritis (LN). Given the limitations of clinical mar...
Decoding tryptophan: Pioneering new frontiers in systemic lupus erythematosus [0.03%]
破译色氨酸密码：在系统性红斑狼疮领域取得的开创性进展
Fugang Huang,Ke Sun,Jiawang Zhou et al.
Fugang Huang et al.
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that affects multiple organ systems, with its pathogenesis intricately tied to genetic, environmental, and immune regulatory factors. In recent years, the aberration of tryp...
Linjie Yang,Song Guo Zheng
Linjie Yang
The liver is the human body's largest digestive gland, which can participate in digestion, metabolism, excretion, detoxification and immunity. Chronic liver diseases such as metabolic dysfunction-associated fatty liver disease (MAFLD) or vi...
Interaction between gut microbiota and T cell immunity in colorectal cancer [0.03%]
肠道微生物群与结肠癌T细胞免疫的相互作用
Zhuang Jing,Wu Yinhang,Chu Jian et al.
Zhuang Jing et al.
This review delves into the complex and multi-layered mechanisms that govern the interaction between gut microbiota and T cells in the context of colorectal cancer (CRC), revealing a novel "microbiota-immune regulatory landscape" within the...
Huifang Hu,Guangyue Zhang,Tao Chen et al.
Huifang Hu et al.
Autoimmune diseases (AIDs) are a group of disorders in which the immune system mistakenly attacks the body's own tissues, characterized by the loss of tolerance to self-antigens and destruction of tissues. Aging is a natural process of phys...