STING-inflammasome axis in autoimmune diseases and inflammation-related disease [0.03%]
STING-炎性小体轴在自身免疫病和炎症相关疾病中的作用
Shengjun Chai,Haiming Xu,Ruixin Liu et al.
Shengjun Chai et al.
The STING-inflammasome axis predominantly functions to transmit signals generated from cGAS-STING-mediated cytosolic DNA recognition, thereby inducing and potentiating inflammasome activation and amplifying immune responses. However, under ...
Specialized pro-resolving mediators and autoimmunity: Recent insights and future perspectives [0.03%]
特异性促解决介质与自身免疫：最新见解和未来前景
Marta Vomero,Ludovica Lamberti,Erika Corberi et al.
Marta Vomero et al.
Inflammation is a response to injuries involving multiple cellular and molecular mechanisms. Different stimuli, such as trauma or microbial invasion, trigger an acute inflammatory response consisting, at least in principle, of two phases: i...
Monoclonal Gammopathy of Rheumatologic Significance (MGRhS): a systemic vision of clonal disorders with multiple organ involvement [0.03%]
风湿病学意义的单克隆免疫球蛋白血症(MGRhS)：多器官受累的克隆性疾病的系统性观点
Luca Quartuccio,Valeria Manfrè,Elena Treppo et al.
Luca Quartuccio et al.
Monoclonal gammopathy (MG) encompasses a spectrum of conditions ranging from benign to malignant clonal B-cell proliferations. While MG is traditionally associated with hematologic malignancies, its role in autoimmune and rheumatologic dise...
Intersecting paths between autoimmunity and bone marrow fibrosis: the case of autoimmune myelofibrosis [0.03%]
自身免疫与骨髓纤维化之间交叉的发病机制路径：以自身免疫性骨髓纤维化为例
Francesco Carubbi,Alessia Alunno,Elisa Matone et al.
Francesco Carubbi et al.
Bone marrow fibrosis is frequently observed in patients with haematological malignancies including myeloproliferative neoplasm (MPNs). The most common cause of BMF is the BCR-ABL-negative MPN primary myelofibrosis (PMF) however, BMF may als...
Understanding the effects of Janus kinase inhibitors on the cardiovascular system in comparison to main biological DMARDs in rheumatoid arthritis [0.03%]
janus激酶抑制剂与传统生物制剂dmard相比对类风湿关节炎患者心血管系统的影响：理解两者差异
Aliki Zavoriti,Pierre Miossec
Aliki Zavoriti
Rheumatoid arthritis (RA) is linked to increased cardiovascular (CV) risk, as is typical for systemic inflammation. The systemic effects of inflammatory cytokines induce vascular dysfunction, leading to thrombosis and other CV diseases. Red...
Primordial and primary prevention in rheumatological diseases: The time has come [0.03%]
原始性和一级预防在风湿性疾病中的应用：是时候采取行动了
Laura Scagnellato,Mariangela Salvato,Luca Iorio et al.
Laura Scagnellato et al.
Rheumatological, immune-mediated diseases (RDs) impose a substantial global burden, especially on women of working age, resulting in chronic disability and escalating healthcare utilisation. Despite therapeutic advances, the incidence of RD...
Fabiola Atzeni,Javier Rodríguez-Carrio,Alessandra Alciati et al.
Fabiola Atzeni et al.
It is now widely recognized that patients with psoriatic arthritis (PsA) have a higher risk of cardiovascular disease (CVD) when compared with the general population. A number of factors contribute to this increased risk. Skin and articular...
Social determinants of health and disparities across the patient pathway in systemic lupus erythematosus: A narrative review [0.03%]
系统性红斑狼疮患者治疗路径中的社会健康决定因素和差异：综述文章
Daniel Guimarães de Oliveira,Zoe Karakikla-Mitsakou,Lena Koskina et al.
Daniel Guimarães de Oliveira et al.
Objective: Systemic Lupus Erythematosus (SLE) is a complex, chronic autoimmune disease with significant heterogeneity in its presentation and progression. Social determinants of health (SDH), including socioeconomic facto...
Exploring vaccine safety and adverse events in major autoimmune diseases [0.03%]
探索主要自身免疫性疾病疫苗的安全性及不良事件
Shabnam Sodagari,Nassim Sodagari
Shabnam Sodagari
This study evaluates post-vaccination adverse events by analyzing a large dataset of patients with major autoimmune diseases, including Hashimoto's n=26,330; Rheumatoid Arthritis n=9,251; psoriasis n=5,589; Systemic Lupus Erythematosus n=4,...
Breast and gynecological cancer risk in systemic lupus erythematosus: A meta-analysis of cohort studies [0.03%]
系统性红斑狼疮患者乳腺和妇科肿瘤的发病风险：队列研究的荟萃分析
Yuejie Lu,Hejing Pan,Chengping Wen et al.
Yuejie Lu et al.
Objective: To evaluate the association between systemic lupus erythematosus (SLE) and the risk of breast and gynecological cancers through a systematic review and meta-analysis of cohort studies. ...