Sporadic late-onset nemaline myopathy (SLONM): Data from a case series and literature review of 144 patients [0.03%]
散发性晚发性肌内膜病（SLONM）：144例患者系列和文献回顾数据
Antonio Lauletta,Francesca Forcina,Gioia Merlonghi et al.
Antonio Lauletta et al.
Sporadic Late-Onset Nemaline Myopathy (SLONM) is an acquired myopathy presenting in adulthood with progressive proximal and axial muscle weakness. A substantial proportion of cases are associated with monoclonal gammopathy of undetermined s...
Regulated cell death in systemic lupus erythematosus: Key pathways and targeted therapies [0.03%]
系统性红斑狼疮中的细胞凋亡调控：关键通路与靶向治疗
Siying Deng,Ziwei Hu,Shaozhe Cai et al.
Siying Deng et al.
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by pathological auto-antibody production and severe immune dysregulation. Dysfunction in regulated cell death (RCD) pathways is crucial in SLE development. Ab...
Senescent CD4+ T cells and autoimmune diseases: Mechanisms and therapeutic prospects [0.03%]
衰老的CD4+t细胞和自身免疫疾病：机制与治疗前景
Yue Hu,Liting He,Hai Long
Yue Hu
Senescent CD4⁺ T cells exhibit classical features of T-cell senescence-including telomere attrition, reduced proliferative capacity, and an upregulated senescence-associated secretory phenotype (SASP)-while also displaying unique character...
Jan Willem Cohen Tervaert
Jan Willem Cohen Tervaert
Many different drugs and/or vaccines may cause vasculitis which can be sometimes very severe. The clinical presentation varies from isolated skin vasculitis to multi-organ involvement with pulmonary-renal manifestations and/or cerebral vasc...
Ferritinophagy in inflammatory and autoimmune diseases: Mechanistic insights and therapeutic potentials [0.03%]
铁死亡与炎症和自身免疫疾病：机制见解与治疗潜力
Yi Wang,Yang Li,Jiani Jiang et al.
Yi Wang et al.
Ferritinophagy, a selective form of autophagy mediated by nuclear receptor coactivator 4 (NCOA4), degrades ferritin to regulate intracellular iron homeostasis and has emerged as an important process in inflammatory and autoimmune diseases. ...
Are the 2023 ACR/EULAR classification criteria a step forward in the management of antiphospholipid syndrome? A literature-based and clinical practice appraisal [0.03%]
2023年ACR/EULAR分类标准在抗磷脂综合征管理中的进步：基于文献和临床实践的评估
Jaume Alijotas-Reig,Joana Marques-Soares,Enrique Esteve-Valverde et al.
Jaume Alijotas-Reig et al.
Antiphospholipid syndrome (APS) is an autoimmune disease (AID) without defined diagnostic criteria, but having classification criteria, as happens in most AID. Until 2023, we were using 2006 Sydney classification criteria. Although they had...
Environmental toxins and toxic metals in autoimmune diseases: Sex differences, hormonal influences, and immune dysregulation [0.03%]
环境毒素和有毒金属在自身免疫疾病中的作用：性别差异、激素影响和免疫功能紊乱
Geir Bjørklund,David R Wallace,Kimiya Kangarlou et al.
Geir Bjørklund et al.
Environmental toxins, including toxic metal(oid)s such as mercury, lead, cadmium, and arsenic, as well as endocrine-disrupting chemicals like bisphenol A and phthalates, play a critical role in the onset and progression of autoimmune diseas...
Extending the discussion: Cannabis based therapies in inflammatory bowel disease a letter to the editor [0.03%]
来信：大麻基疗flammatory bowel disease的治疗药物疗法讨论续论
Laxmikausthubha Yaratha,Anushka Deogaonkar,Marie L Borum
Laxmikausthubha Yaratha
Frank Verhoeven,Dalil Hannani,Céline Demougeot et al.
Frank Verhoeven et al.
Interleukin-33 (IL-33), an alarmin released upon tissue stress or damage, has gained increasing interest in the pathophysiology of inflammatory diseases such as spondyloarthritis (SpA). Acting through its receptor ST2, IL-33 contributes to ...
VE/VCO2 at ventilatory threshold and peak VO2 in CPET studies of patients with scleroderma-associated PAH: A systematic review and meta-analyses [0.03%]
系统性回顾与荟萃分析评估联合肺功能测定研究中硬皮病相关肺动脉高压患者通气阈值处VE/VCO2和峰值VO2的情况
Julie Better,Sylvie Leroy,Maarten K Ninaber et al.
Julie Better et al.
Context: Pulmonary arterial hypertension (PAH) is one of the leading causes of mortality in patients with systemic sclerosis (SSc). Cardiopulmonary exercise testing (CPET) has been studied to detect SSc-associated PAH. ...