Differences in withdrawal symptoms, microglia activity, and cognitive functioning in rats exposed to continuous low-dose heroin in-utero [0.03%]
宫内连续低剂量海洛因暴露大鼠的戒断症状、小胶质细胞活性及认知功能差异
Sara L Mills-Huffnagle,Charles N Zawatsky,Gjhvona Bryant et al.
Sara L Mills-Huffnagle et al.
Introduction: Opioid use during pregnancy and subsequent neonatal opioid withdrawal syndrome (NOWS) have been associated with poor developmental outcomes including cognitive functioning. Less is known about the underlying...
Adolescent exposure to bisphenol-a antagonizes androgen regulation of social behavior in male mice [0.03%]
雄性小鼠青春期暴露于双酚A反向调节雄激素的社会行为调控作用
Xiaoyu Zhong,Jisui Li,Xiaohong Xu
Xiaoyu Zhong
Social behavior is sexually dimorphic, which is regulated by gonadal hormones in the brain. Our recent study found that exposure to low doses of bisphenol-A (BPA) during adolescence, permanently alters social behavior in adult male mice, bu...
Introduction to "Effects of per- and polyfluoroalkyl substances (PFAS) within a developmental context" [0.03%]
《从发育角度介绍per-和polyfluoroalkyl化学物质(PFAS)的影响》
Helen J K Sable,Francheska M Merced-Nieves,Jerrold S Meyer
Helen J K Sable
Tyrosinase inhibition prevents non-coplanar polychlorinated biphenyls and polybrominated diphenyl ethers-induced hyperactivity in developing zebrafish: Interaction between pigmentation and neurobehavior [0.03%]
酪氨酸酶抑制可预防多氯联苯和多溴二苯醚所致发育斑马鱼多动行为：色素沉着与神经行为之间的相互作用
Yasuaki Tanaka,Asako Shindo,Wenjing Dong et al.
Yasuaki Tanaka et al.
Non-coplanar polychlorinated biphenyl (PCB) mixture Aroclor 1254 and polybrominated diphenyl ether (PBDE) BDE-47 are known to impede neurogenesis and neuronal development. We previously reported that exposure to PCB and PBDE leads to increa...
Prenatal tobacco and tobacco-cannabis co-exposure: Relationship with attention and memory in middle childhood [0.03%]
孕期烟草暴露及伴随大麻烟暴露与学龄前儿童注意力和记忆力的关系
Shannon Shisler,Jin-Kyung Lee,Nicolas J Schlienz et al.
Shannon Shisler et al.
We examined associations between prenatal tobacco exposure (with and without cannabis exposure) and children's performance on laboratory measures of sustained attention, attentional set shifting, and working memory in middle childhood (9-12...
Neurotoxicity assessment of the herbicide pethoxamid in zebrafish (Danio rerio) embryos/larvae [0.03%]
杀虫剂戊草胺对斑马鱼胚胎/幼体神经毒性的评估
Cole D English,Emma Ivantsova,Lev Avidan et al.
Cole D English et al.
Pethoxamid, a member of the chloroacetamide herbicide family, is a recently approved chemical for pre- or post-emergence weed control; however, toxicity data for sublethal effects in aquatic organisms exposed to pethoxamid are non-existent ...
Effects of maternal LPS and developmental exposure to an environmentally relevant phthalate mixture on neuron number in the rat medial prefrontal cortex [0.03%]
母体LPS和发育期接触环境相关水平的邻苯二甲酸酯混合物对大鼠前额叶皮层神经元数量的影响
V R Riesgo,E P Sellinger,A S Brinks et al.
V R Riesgo et al.
The brain is especially vulnerable to environmental influences during the perinatal period. While the effects of environmental factors are usually studied in isolation, it is more typical to be exposed to multiple influences during early de...
Lauren M Jansson,Krystle McConnell,Martha L Velez et al.
Lauren M Jansson et al.
Background: Buprenorphine-naloxone treatment may confer substantial benefits for the treatment of opioid use disorder (OUD) during pregnancy including lower risk for overdose/death, less diversion potential and reduced us...
Preconception ethanol exposure changes anxiety, depressive and checking-like behavior and alter the expression levels of MAO-B in male offspring [0.03%]
孕前乙醇暴露改变子代小鼠焦虑、抑郁和检查型行为以及多巴胺分解代谢相关基因MAO-B的表达水平
Mohammad Basir Asefi,Amirhossein Heidari,Arman Hajikarim-Hamedani et al.
Mohammad Basir Asefi et al.
Alcohol use, which alters the epigenome, increases the probability that it could affect subsequent generations, even if they were never directly exposed to ethanol or even in utero. We explored the effects of parental ethanol exposure befor...
Long-term effects of Preweaning environmental impoverishment on neurobehavioral and neurocognitive outcomes in Sprague Dawley rats: An early environmental stress model [0.03%]
早期环境应激模型中仔鼠早期环境贫乏对Sprague-Dawley大鼠神经行为和神经认知结局的长期影响
Charles V Vorhees,Robyn M Amos-Kroohs,Michael T Williams
Charles V Vorhees
Developmental stress, including low socioeconomic status (SES), can induce dysregulation of the hypothalamic-pituitary-adrenal axis and result in long-term changes in stress reactivity. Children in lower SES conditions often experience more...