A pilot autism case-control study of pesticides and plasticizers in shed baby teeth [0.03%]
婴儿乳牙中农药和塑化剂的自体脱落牙齿病例对照研究试点项目
Lynne P Heilbrun,Inkyu Han,Anabel Rodriguez et al.
Lynne P Heilbrun et al.
Even moderate exposures to pesticides and plasticizers have been associated with neurotoxicity and autism characteristics; however, most studies of urine and blood provide a short-term exposure window compared to teeth, which capture long-t...
Effects of subchronic late-gestational nicotine exposure on postpartum maternal behavior in Wistar rats: An exploratory pilot study [0.03%]
妊娠晚期亚慢性尼古丁暴露对Wistar大鼠产后母性行为影响的探索性研究
Wilmer Yamid González-Cabra,María Del Pilar Santacruz Ortega,Andrés Carrillo-González
Wilmer Yamid González-Cabra
Objective: This exploratory pilot study evaluated whether subchronic late-gestational oral nicotine exposure alters postpartum maternal behavior in Wistar rats. ...
Periconceptional and prenatal tobacco exposure and early externalizing behavior: Developmental pathways through maternal distress and language delay [0.03%]
孕前和宫内烟草暴露与早期外化行为：通过母体痛苦和语言发育迟缓的发展途径
Madeleine Singer,Julie A Kable,Claire D Coles
Madeleine Singer
Periconceptional and prenatal tobacco exposure (PPTE) has been associated with early externalizing behaviors, yet the developmental pathways underlying this association remain poorly understood. The purpose of this study was to examine pote...
Evidence of decreased neural efficiency supporting fluid reasoning abilities in children and adolescents chronically exposed to home radon [0.03%]
长期接触室内氡气对儿童和青少年流体智力神经机制的影响研究
Sarah L Greenwood,Haley R Pulliam,Monica N Clarke-Smith et al.
Sarah L Greenwood et al.
Fluid reasoning (Gf), the ability to solve novel problems without prior knowledge, is a highly integrative skill with far-reaching impacts on multiple domains of functioning including attention and working memory. Gf abilities like abstract...
Spermatogenic timing, dose, and route of administration as determinants of paternal transmission of developmental neurotoxicity [0.03%]
精母细胞发生的时间、剂量和给药途径决定的发育神经毒性的父系传递
Issam Rimawi,Joseph Yanai
Issam Rimawi
Growing evidence challenges the long-standing assumption that the paternal germline is insulated from environmental perturbation and identifies preconception paternal exposure as an underrecognized pathway of developmental neurotoxicity. Ac...
Prenatal methamphetamine exposure increased addiction vulnerability through neural circuit dysfunction and epigenetic modifications in offspring [0.03%]
孕期苯丙胺暴露通过后代神经回路功能障碍和表观遗传修饰增加成瘾易感性
Yuqi Wang,Daiju Tao,Rongji Sun et al.
Yuqi Wang et al.
Methamphetamine (METH), a type of synthetic drug with effects similar to amphetamines, remains a significant public health concern, particularly among women of childbearing age. Prenatal methamphetamine exposure (PME) has been demonstrated ...
Postnatal environment differentially modulates neurodevelopmental outcomes following voluntary prenatal oxycodone exposure in rats [0.03%]
自愿吸入羟考酮的妊娠大鼠后代神经发育结局受产后环境影响不同
Kelsea R Gildawie,Kerri E Budge,Sara B Isgate et al.
Kelsea R Gildawie et al.
As prenatal opioid exposure becomes increasingly prevalent, understanding which neurodevelopmental effects are amenable to postnatal intervention has become a critical question. Clinically, prenatal exposure and maternal factors that affect...
Electroacupuncture mitigates cognitive impairment caused by anesthesia and surgery in aged rats by inhibiting the p38 MAPK signaling pathway [0.03%]
电针通过抑制p38丝裂原活化蛋白激酶信号通路缓解老年大鼠术后认知功能障碍
Bin Cheng,Qian He,Dan Ge et al.
Bin Cheng et al.
Electroacupuncture (EA) effectively enhances postoperative cognitive function in the elderly, though its underlying mechanism remains largely unexplored. This study aimed to explore the role of the p38 MAPK signaling pathway in how EA allev...
Pediatric neurotoxicity in Morocco: Epidemiology, clinical profile, toxicology findings and outcomes [0.03%]
摩洛哥儿童神经毒性：流行病学、临床特征、毒理学发现及转归
Sahar Amrani Hanchi,Youssra Metarfi,Fatima Zahrae Bartal et al.
Sahar Amrani Hanchi et al.
Background and objectives: Pediatric neurotoxicity remains a major cause of morbidity and mortality in low- and middle-income countries. In Morocco, the burden of toxic exposures leading to neurological disorders is still...
Prenatal cannabidiol exposure alters physical and behavioral development in rats [0.03%]
大麻二酚 prenatal暴露会影响大鼠的生长发育和行为学表现
Ilse Fleischer,Jennifer D Thomas
Ilse Fleischer
Recently, it has been reported that 20% of pregnant women in the U.S. and Canada use cannabidiol (CBD) during pregnancy (Bhatia et al., 2024). The common perception is that CBD exposure is harmless to the fetus. However, the effects of CBD ...