Long-term neurological and neurocognitive deficits in adults prenatally exposed to methylmercury: Minamata disease [0.03%]
prenatal暴露于甲基汞的成人长期神经和神经认知缺陷：水俣病
Takashi Yorifuji,Yuka Yamamura,Itsuka Nagano et al.
Takashi Yorifuji et al.
Minamata disease, officially recognized in 1956, is a well-known food poisoning event that was caused by the consumption of fish and seafood contaminated with methylmercury. Although patients with congenital Minamata disease (CMD) with seve...
S-adenosyl-L-methionine reverses ethanol-induced developmental toxicity in FASD model of Danio rerio embryos via dual-modulation of oxidative stress and glutathione homeostasis [0.03%]
腺苷蛋氨酸通过双重调节氧化应激和谷胱甘肽稳态逆转斑马鱼胚胎酒精诱导的发育毒性模型中的FASD
Prasanth Babu Nandagopal,Anu Varghese Kaithamattathil,Gopika Jayakrishnan et al.
Prasanth Babu Nandagopal et al.
Fetal Alcohol Spectrum Disorder (FASD) represents a major global public health concern, affecting approximately 7.7 per 1000 births worldwide and remains as the most common preventable cause of lifelong neurodevelopmental impairment. Despit...
Mechanistic links between cadmium and MAPK pathways leading to neurodegeneration [0.03%]
镉通过MAPK途径引起神经退行损伤的机制研究
Sneha De,Shinjini Kanrar,Aluru Parithathvi et al.
Sneha De et al.
Cadmium, a Group 1 carcinogen, represents a significant public health concern due to its widespread environmental distribution and exposure through industrial processes, contaminated water, dietary intake, and tobacco use. Prolonged cadmium...
Gene × environment interaction between latrophilin-3 (Lphn3 or Adgrl3) and developmental permethrin exposure in Sprague Dawley rats [0.03%]
Sprague Dawley大鼠中神经纤连蛋白-3（Lphn3或Adgrl3）基因与发育期溴氰聚酯环境暴露的相互作用研究
Charles V Vorhees,Adam L Fritz,Brooke M Gollaway et al.
Charles V Vorhees et al.
Attention deficit hyperactivity disorder (ADHD) occurs in 9.8% of U.S. children and has a large hereditary component arising from multiple gene variants. One of these is Latrophiln-3 (LPHN-3). Using CRISPR/Cas9 we deleted exon 3 in Sprague ...
Bromelain mitigates monosodium glutamate-induced neurobehavioral impairment in mice by modulating AChE-MAO-GAD and oxido-inflammatory pathways: Experimental and computational insights [0.03%]
菠萝蛋白酶通过调节AChE-MAO-GAD和氧化炎症途径减轻谷氨酸单钠诱导的小鼠神经行为障碍：实验和计算见解
Joseph Chimezie,Noah A Omeiza,Oludare M Ogunyemi et al.
Joseph Chimezie et al.
Excessive exposure to monosodium glutamate (MSG) induces glutamate-mediated excitotoxicity, oxidative stress, and neuroinflammation, culminating in neurobehavioral impairments. Bromelain, a cysteine protease derived from Ananas comosus, exh...
Profiles of polysubstance exposure in youth with fetal alcohol spectrum disorders and the association with neurodevelopmental outcomes [0.03%]
儿童期接触多种物质在胎儿酒精谱系障碍青年中的流行情况及其与神经发育结局的关系
Madeline N Delage,Emily L Speybroeck,Alesia A Richardson et al.
Madeline N Delage et al.
Background: Prenatal polysubstance exposure is highly prevalent among individuals with fetal alcohol spectrum disorders (FASD), yet little research has examined how specific patterns of co-exposure relate to neuropsycholo...
Environmental factors associated with microcephaly in Africa: A systematic review [0.03%]
非洲小头畸形的环境因素：系统性综述
Pelagie Izabayo,Jean Claude Hakizimana,Annette Uwineza et al.
Pelagie Izabayo et al.
Introduction: Microcephaly, a condition characterized by a head circumference below the mean for age and sex, is a significant indicator of impaired fetal brain development. While some environmental factors have been asso...
Gestational and early childhood air pollution exposure and neurodevelopmental outcomes in early childhood [0.03%]
孕期及早年空气污染暴露与幼儿神经发育结局的关系
Christina Berninger,Yingying Xu,Patrick Ryan et al.
Christina Berninger et al.
Background: Exposure to ambient air pollution, including fine particulate matter (PM2.5), nitrogen dioxide (NO2), and elemental carbon, has been associated with worse neurodevelopmental outcomes in children, but research ...
Is there a glymphatic pathway to environmental risk in neurodevelopmental disorders? [0.03%]
环境风险因素通过glymphatic通路影响神经发育障碍吗？
Maiara de Aguiar da Costa,Sofia Januário Bolan,Maria Fernanda Pedro Ebs et al.
Maiara de Aguiar da Costa et al.
The glymphatic system (GS) is a glia-dependent perivascular network that mediates cerebrospinal fluid-interstitial fluid exchange and facilitates the clearance of neurometabolites. GS transport is sleep-dependent, with waste elimination hei...
Neuroprogramming of prenatal phthalate exposures on fluid cognition: A latent variable modeling approach to quantify exposure burden and integrate neurobehavioral data [0.03%]
孕期邻苯二甲酸盐暴露的神经编程对流动认知的影响：采用潜变量模型方法量化暴露负荷并整合神经行为数据
Jamil M Lane,Nathan Cohen,Vishal Midya et al.
Jamil M Lane et al.
Background: Phthalates are endocrine-disrupting chemicals with neuroactive properties linked to maladaptive neurodevelopment in children. However, few studies have utilized latent variable methodologies to estimate their ...