Carvacrol ameliorates behavioral disturbances and DNA damage in the brain of rats exposed to propiconazole [0.03%]
百里酚通过改善过量丙环唑诱导的小鼠行为异常及神经DNA损伤起保护作用
Mohamed A Elhady,Abdel Azeim A Khalaf,Mervat M Kamel et al.
Mohamed A Elhady et al.
Propiconazole (PCZ) is an ergosterol biosynthesis inhibiting fungicide. Carvacrol (CAR) is a monoterpenoid phenol that has various beneficial health effects. The current research was designed to study the impact of PCZ on the behavior of ra...
Silencing brain catalase expression reduces ethanol intake in developmentally-lead-exposed rats [0.03%]
发育性铅暴露大鼠中沉默脑型过氧化氢酶表达可减少乙醇摄入量
Mara Soledad Mattalloni,Paula Alejandra Albrecht,Catalina Salinas-Luypaert et al.
Mara Soledad Mattalloni et al.
Lead (Pb) is a developmental neurotoxicant. We have demonstrated that perinatally Pb-exposed rats consume more ethanol than their control counterparts, a response that seems to be mediated by catalase (CAT) and centrally-formed acetaldehyde...
Antiapoptotic effect of taurine against NMDA-induced retinal excitotoxicity in rats [0.03%]
牛磺酸对谷氨酸诱导的视网膜神经细胞凋亡的保护作用
Lidawani Lambuk,Igor Iezhitsa,Renu Agarwal et al.
Lidawani Lambuk et al.
Objective: N-methyl-D-aspartate (NMDA) excitotoxicity has been proposed to mediate apoptosis of retinal ganglion cells (RGCs) in glaucoma. Taurine (TAU) has been shown to have neuroprotective properties, thus we examined ...
Adolescent methylmercury exposure: Behavioral mechanisms and effects of sodium butyrate in mice [0.03%]
小鼠甲基汞暴露：行为机制及丁酸钠的影响
Steven R Boomhower,M Christopher Newland
Steven R Boomhower
Methylmercury (MeHg), an environmental neurotoxicant primarily found in fish, produces neurobehavioral impairment when exposure occurs during gestation. Whether other developmental periods, such as adolescence, display enhanced vulnerabilit...
Exposure to pesticides and the prevalence of diabetes in a rural population in Korea [0.03%]
韩国农村人口农药暴露与糖尿病患病率的关系研究
Sungjin Park,Sung-Kyung Kim,Jae-Yeop Kim et al.
Sungjin Park et al.
Background: Among the adverse health effects of exposure to pesticides, an association with diabetes has been reported. However, there is a lack of epidemiologic studies on the health effects of exposure to pesticides, pa...
6-Hydroxydopamine induces different mitochondrial bioenergetics response in brain regions of rat [0.03%]
6-羟基多巴胺诱导大鼠脑区不同的线粒体生物能量学响应
Débora F Gonçalves,Aline A Courtes,Diane D Hartmann et al.
Débora F Gonçalves et al.
Mitochondrial dysfunction has been demonstrated to have a central role in Parkinson Disease (PD) pathophysiology. Some studies have indicated that PD causes an impairment in mitochondrial bioenergetics; however, the effects of PD on brain-r...
Corticosterone and pyridostigmine/DEET exposure attenuate peripheral cytokine expression: Supporting a dominant role for neuroinflammation in a mouse model of Gulf War Illness [0.03%]
皮质酮和吡啶斯的明/DEET暴露可减弱外周细胞因子表达：支持神经炎症在海湾战争疾病小鼠模型中占主导作用的观点
Lindsay T Michalovicz,Alicia R Locker,Kimberly A Kelly et al.
Lindsay T Michalovicz et al.
Gulf War Illness (GWI) is a chronic multi-symptom disorder experienced by as many as a third of the veterans of the 1991 Gulf War; the constellation of "sickness behavior" symptoms observed in ill veterans is suggestive of a neuroimmune inv...
Neurobehavioral and oxidative stress alterations following methylmercury and retinyl palmitate co-administration in pregnant and lactating rats and their offspring [0.03%]
协同施用甲基汞和硬脂棕榈酸酯后妊娠及哺乳大鼠及其子代神经行为与氧化压力的变化
Pedro Espitia-Pérez,Suelen Marin Albino,Lyda Espitia-Pérez et al.
Pedro Espitia-Pérez et al.
Fish consumption and ubiquitous methylmercury (MeHg) exposure represent a public health problem globally. Micronutrients presented in fish affects MeHg uptake/distribution. Vitamin A (VitA), another fish micronutrient is used in nutritional...
Multiple effects of the herbicide glufosinate-ammonium and its main metabolite on neural stem cells from the subventricular zone of newborn mice [0.03%]
除草剂谷氨酰胺酸铵及其主要代谢产物对新生小鼠脑侧伏隔核区神经干细胞的多效性影响
Justyne Feat-Vetel,Vanessa Larrigaldie,Géraldine Meyer-Dilhet et al.
Justyne Feat-Vetel et al.
The globally used herbicide glufosinate-ammonium (GLA) is structurally analogous to the excitatory neurotransmitter glutamate, and is known to interfere with cellular mechanisms involved in the glutamatergic system. In this report, we used ...
Prenatal exposure to organochlorine pesticides and early childhood communication development in British girls [0.03%]
孕期有机氯农药暴露与英国女童早期语言发育的关系研究
Zuha Jeddy,Katarzyna Kordas,Kristen Allen et al.
Zuha Jeddy et al.
Background: The developing brain is susceptible to exposure to neurodevelopmental toxicants such as pesticides. Aims: We explored assoc...