The Sweet Gatekeeper: Mucin-Type O-Glycans in Brain Endothelial Glycocalyx and Aging [0.03%]
甜门卫：脑内皮糖萼寡糖蛋白O-连接型糖基化在衰老中的作用
Duan Lu Hou,Yun-Cheng Wu,Eng King Tan et al.
Duan Lu Hou et al.
The blood-brain barrier (BBB) is crucial for brain homeostasis, and its dysfunction is associated with aging and neurodegenerative diseases. A recent seminal study by Shi et al. (2025) published in Nature illuminates a previously underappre...
Kartini I Vosshage,James R Swift,Ayoung Kim et al.
Kartini I Vosshage et al.
The growing ageing population presents significant challenges for healthcare systems, particularly in monitoring age-related physiological decline. Ageing is a complex, multifactorial process that manifests without specific symptoms and is ...
The emerging role of the melatonin-cortisol axis: bridging aging-related biomarkers to environment-driven aging research [0.03%]
褪黑素-皮质醇轴在衰老研究中的新兴作用：连接衰老标志物与环境驱动的衰老研究桥梁
Xiong Chen,Dapeng Wang,Junyan Tao et al.
Xiong Chen et al.
The aging process is predominantly influenced by genetic and environmental factors. Environmental factors that accelerate biological aging, known as gerontogens, increase organismal vulnerability and susceptibility to disease, thereby eleva...
Linking mitochondrial DNA release to neurodegeneration and cognitive decline [0.03%]
线粒体DNA释放与神经退行性及认知衰退之间的关联研究
Zongwei Fang,Catarina Barbosa,Daniela Marinho et al.
Zongwei Fang et al.
Mitochondrial DNA (mtDNA) has been recognized as a key link between mitochondrial dysfunction and neuroinflammation in neurodegenerative diseases. Beyond being a vulnerable target of oxidative damage, mtDNA can act as a damage-associated mo...
Age-related sarcopenia and the gut microbiome: mechanistic insights into the gut-muscle axis and potential microbiome based therapeutic interventions [0.03%]
年龄相关性肌肉减少症与肠道微生物组：肠肌轴的机制见解及潜在的微生物治疗干预措施
Sophie L Allen,Leigh Breen,Janet M Lord et al.
Sophie L Allen et al.
Ageing is associated with a loss of skeletal muscle mass, strength and function, termed sarcopenia. The presence of sarcopenia is known to be problematic leading to an increased risk of falls, fractures and mortality. Age-related changes in...
The turquoise killifish (Nothobranchius furzeri) as emerging ageing model: Systematic review and comparison with zebrafish, medaka and Fugu [0.03%]
耳突沙塘鳢(NOthobranchius furzeri)作为新兴衰老模型：系统评价及与斑马鱼、鲤鱼和河豚的比较
Chen Li,Svante Winberg,Chengxi Sun et al.
Chen Li et al.
Selecting the most appropriate model organisms is crucial for studying ageing and ageing-related diseases. While vertebrate aging models offer valuable research feasibility due to their biological complexity and human relevance, their inher...
Corrigendum to "Ageing and liver immune cells" [Ageing Res. Rev. 115 (2026) 103039] [0.03%]
关于“衰老与肝脏免疫细胞”一文的勘误( Aging Res. Rev. 115 (2026) 103039)
Jarrod J Kennedy,Patrick Bertolino,Sophie Lucic Fisher et al.
Jarrod J Kennedy et al.
Published Erratum
Ageing research reviews. 2026 Feb 18:103063. DOI:10.1016/j.arr.2026.103063 2026
Adiponectin and Aging: Mechanistic Insights, Clinical Paradox, and Therapeutic Horizons [0.03%]
脂联素与衰老：机制见解、临床悖论及治疗前景
Eric R McGregor,Katie J Osterbauer,Grace E Gustafson et al.
Eric R McGregor et al.
Adiponectin is an adipose tissue-derived peptide hormone that exerts beneficial metabolic effects in many tissues throughout the body. It is most well-known for its ability to enhance insulin sensitivity and dampen chronic inflammation. The...
Functional cognitive screening instruments and their clinical utility with older adults in the emergency department: A systematic review [0.03%]
急诊科老年人功能性认知筛查工具及临床应用价值系统评价
Francis S Gomes,Justin Newton Scanlan,Anne Cusick et al.
Francis S Gomes et al.
Cognitive screening is a vital part of geriatric emergency department (ED) care. Performance-based functional cognitive measures may better identify impairments and predict post-discharge outcomes in daily activities. Currently, there is no...
Quality and recommendations of guidelines for multimorbidity and polypharmacy in older adults: A systematic review [0.03%]
老年多重疾病及多重用药指南的质量和推荐意见：系统综述
Jiang Yang,Huiru Li,Yaolong Chen et al.
Jiang Yang et al.
Background: Global population aging exacerbates the challenges of multimorbidity and polypharmacy in older adults. Clinical practice guidelines are essential for addressing these issues. This systematic review aims to eva...