Irene Jiménez-Salvador,Patricia Meade,Eldris Iglesias et al.
Irene Jiménez-Salvador et al.
Numerous pesticides are inhibitors of the oxidative phosphorylation system. Oxidative phosphorylation dysfunction adversely affects neurogenesis and often accompanies Parkinson disease. Since brain development occurs mainly in the prenatal ...
Elena Yushkova,Alexey Moskalev
Elena Yushkova
Transposable elements (TEs) are an important part of eukaryotic genomes. The role of somatic transposition in aging, carcinogenesis, and other age-related diseases has been determined. This review discusses the fundamental properties of TEs...
Yaling Wu,Milu Li,Jinjin Zhang et al.
Yaling Wu et al.
Uterine aging is an important factor that impacts fertility, reproductive health, and uterus-related diseases; however, it remains poorly explored. Functionally, these disturbances have been associated with an abnormal hormonal response in ...
RNA-binding proteins in degenerative joint diseases: A systematic review [0.03%]
退行性关节疾病中的RNA结合蛋白：系统综述
Min Xiang,Ling Liu,Tingrui Wu et al.
Min Xiang et al.
RNA-binding proteins (RBPs), which are conserved proteins comprising multiple intermediate sequences, can interact with proteins, messenger RNA (mRNA) of coding genes, and non-coding RNAs to perform different biological functions, such as t...
Kun Li,Ziqiang Wang
Kun Li
Neurodegenerative diseases are the most common causes of disability worldwide. Given their high prevalence, devastating symptoms, and lack of definitive diagnostic tests, there is an urgent need to identify potential biomarkers and new ther...
Jian Luo
Jian Luo
Astrocytes are highly polarized neuroglial cells. Polarity is the basis for many of the diverse roles that astrocytes play in the normal and injured brain. Astrocytes are generally dormant and non-migratory under normal physiological condit...
Physical activity for cognitive health promotion: An overview of the underlying neurobiological mechanisms [0.03%]
促进认知健康的体育活动：潜在神经生物学机制概述
Chong Chen,Shin Nakagawa
Chong Chen
Physical activity is one of the modifiable factors of cognitive decline and dementia with the strongest evidence. Although many influential reviews have illustrated the neurobiological mechanisms of the cognitive benefits of physical activi...
A novel regulator in Alzheimer's disease progression: The astrocyte-derived extracellular vesicles [0.03%]
一种新的调节因子在阿尔茨海默病的进展中起到作用：星形胶质细胞来源的胞外囊泡
Biao Li,Zhixin Ma,Zhigang Li
Biao Li
Alzheimer's disease (AD) is known as an age-related irreversible neurodegenerative disease. AD seriously endangers the health of the elderly, but there is still no effective treatment. In the past several decades, the significant role of as...
The pollutome-connectome axis: a putative mechanism to explain pollution effects on neurodegeneration [0.03%]
污染-脑连接体轴：解释污染对神经退行影响的潜在机制
Lorenzo Pini,Alessandro Salvalaggio,Alexandra M Wennberg et al.
Lorenzo Pini et al.
The study of pollutant effects is extremely important to address the epochal challenges we are facing, where world populations are increasingly moving from rural to urban centers, revolutionizing our world into an urban world. These transfo...
The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's disease [0.03%]
阿尔茨海默病早期海马相关GABA能神经网络损伤
Yuanhong Tang,Yan Yan,Jian Mao et al.
Yuanhong Tang et al.
Alzheimer's disease (AD) is the commonest neurodegenerative disease with slow progression. Pieces of evidence suggest that the GABAergic system is impaired in the early stage of AD, leading to hippocampal neuron over-activity and further le...